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Cat. No. | Product Name | Target | Signaling Pathways |
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T8760 |
NNMTi
5-Amino-1-methylquinolinium |
Others | Others |
NNMTi (5-Amino-1-methylquinolinium) 是烟酰胺 N -甲基转移酶的抑制剂 (IC50=1.2 μM),可选择性地结合 NNMT 底物结合位点残基。它能诱导体外成肌细胞分化,提高老年小鼠肌肉干细胞融合和再生能力。 | |||
T36802 |
Bisubstrate Inhibitor 78
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Bisubstrate inhibitor 78 is an inhibitor of nicotinamide N-methyltransferase (NNMT; IC50= 1.41 μM).1It binds the NNMT active site in the binding pockets for the NNMT substrates S-adenosyl-L-methionine (SAM) and nicotinamide . Bisubstrate inhibitor 78 is selective for NNMT over histone-lysine N-methytransferase NSD2 and protein arginine methyltransferase 1 (PRMT1; IC50s = >50 μM for both). It reduces levels of 1-methylnicotinamide in, and inhibits proliferation of, HSC-2 oral cancer cells when us... |
Cat. No. | Product Name | Species | Expression System |
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TMPY-01011 |
FGFR1 Protein, Human, Recombinant (His)
KAL2,FLT2,FGFBR,HRTFDS,OGD,FLG,HBGFR,bFGF-R-1,CD331,fibrobla... |
Human | HEK293 Cells |
FGFR1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31 kDa and the accession number is H9FRD4. | |||
TMPY-06036 |
FGFR1 Protein, Human, Recombinant (alpha (IIIb), His)
FGFR-1,FLG,CD331,HH2,FLT2,KAL2,FGFBR,HBGFR,CEK,HRTFDS,fibrob... |
Human | HEK293 Cells |
FGFR1 Protein, Human, Recombinant (alpha (IIIb), His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.5 kDa and the accession number is P11362-7. | |||
TMPY-06034 |
FGFR1 Protein, Human, Recombinant (beta (IIIb), His)
FLG,CD331,N-SAM,HBGFR,HRTFDS,BFGFR,OGD,KAL... |
Human | HEK293 Cells |
FGFR1 Protein, Human, Recombinant (beta (IIIb), His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.8 kDa and the accession number is H9FRD4. | |||
TMPK-00392 |
FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi)
CD331,FGFR-1,FLT-2,BFGFR,N-sam,FGFR1 β (II... |
Human | HEK293 Cells |
Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabolism, and death. Overexpression of FGFR1 is observed in numerous tumors and thus constitutes an attractive molecular target for selective cancer treatment. FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 25.23 kDa and the accession numb... | |||
TMPK-00394 |
FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
FGFR1 β (IIIc),N-sam,FLT-2,BFGFR,bFGF-R-1,... |
Human | HEK293 Cells |
Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabolism, and death. Overexpression of FGFR1 is observed in numerous tumors and thus constitutes an attractive molecular target for selective cancer treatment. FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 25.23 kDa and the ... | |||
TMPY-06033 |
FGFR1 Protein, Human, Recombinant (beta (IIIb), hFc)
HBGFR,BFGFR,bFGF-R-1,FLG,FGFR-1,fibroblast growth factor rec... |
Human | HEK293 Cells |
FGFR1 Protein, Human, Recombinant (beta (IIIb), hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56 kDa and the accession number is H9FRD4. | |||
TMPY-05761 |
FGFR1 Protein, Human, Recombinant (His), Biotinylated
FLT-2,KAL2,FGFBR,HRTFDS,BFGFR,fibroblast growth factor recep... |
Human | HEK293 Cells |
FGFR1 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31 kDa and the accession number is H9FRD4. | |||
TMPY-04371 |
FGFR1 Protein, Human, Recombinant (His & GST)
HRTFDS,CEK,OGD,FLG,FLT2,FGFBR,bFGF-R-1,N-SAM |
Human | Baculovirus Insect Cells |
FGFR1 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 75 kDa and the accession number is H9FRD4. | |||
TMPY-05777 |
FGFR1 Protein, Human, Recombinant (hFc)
N-SAM,OGD,HH2,HBGFR,FLT2,CEK,FLG,FGFR-1,FG... |
Human | HEK293 Cells |
FGFR1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56.15 kDa and the accession number is NP_001341297.1. | |||
TMPY-06035 |
FGFR1 Protein, Human, Recombinant (alpha (IIIb), hFc)
KAL2,OGD,N-SAM,CEK,FLT2,HH2,FLG,CD331,BFGF... |
Human | HEK293 Cells |
FGFR1 Protein, Human, Recombinant (alpha (IIIb), hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65.7 kDa and the accession number is P11362-7. | |||
TMPH-03434 |
BIO3 Protein, S. cerevisiae, Recombinant (His & Myc)
Diaminopelargonic acid synthase,B... |
Saccharomyces cerevisiae | E. coli |
Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor. BIO3 Protein, S. cerevisiae, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 58.7 kDa and the accession number is P50277. | |||
TMPH-03702 |
MTA/SAH nucleosidase Protein, Vibrio cholerae serotype O1, Recombinant (His & Myc)
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Vibrio cholerae | E. coli |
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. MTA/SAH nucleosidase Protein, Vibrio cholerae serotype O1, Recombinant (His & Myc) is expressed in E. coli expression system wit... | |||
TMPH-00188 |
BioAB Protein, Bacteroides fragilis, Recombinant (His & Myc)
Adenosylmethionine-8-amin |
Bacteroides fragilis | E. coli |
Catalyzes two activities which are involved in the biotine biosynthesis: the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism, and the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). BioAB Protein, Bacteroides fragilis, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The p... | |||
TMPJ-01114 |
GAMT Protein, Human, Recombinant (His)
Guanidinoacetate N-methyltran... |
Human | E. coli |
GAMT is a methyltransferase which belongs to the class I-like SAM-binding methyltransferase superfamily. It contains one RMT2 (arginine N-methyltransferase 2-like) domain and is expressed in liver. GAMT converts guanidoacetate to creatine, using S-adenosylmethionine as the methyl donor. Defects in GAMT are the cause of guanidinoacetate methyltransferase deficiency, which is an autosomal recessive disorder characterized by developmental delay/regression, mental retardation, severe disturbance of ... |