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16

抑制剂 & 化合物

22

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T76653 Polybia-MP1

Polybia-MP1 是一种抗菌素乳苦菌肽。
T80585 Anti-Mouse GM-CSF Antibody (MP1-22E9)

c-Fms Tyrosine Kinase/Adaptors
Anti-MouseGM-CSFAntibody 为特异性针对小鼠GM-CSF的IgG2a类免疫球蛋白抗体,由大鼠血清中提取。
T69977 BC-1485

BC-1485 is a first-in-class inhibitor of Fibrosis-inducing E3 ligase 1 (FIEL1 ), which disrupts FIEL1-directed PIAS4 ubiquitination.
T71901 MP-1

MP-1 is a covalent inhibitor of fumarate hydratase (FH) that exhibits cytotoxicity dependent on FH. MP-1 engages a functional cysteine in the Zn-finger domain of the tRNA methyltransferase enzyme TRMT1.
T16124 MMP13-IN-3

MMP Proteases/Proteasome
MMP13-IN-3 是口服有效的MMP-13选择性抑制剂,IC50为 1 nM,比其他 MMP 的选择性高 1000倍多。MMP13-IN-3在用于骨关节炎方面有研究的价值。
T3983 TMP195

TFMO 2,TMP 195

HDAC Chromatin/Epigenetic; DNA Damage/DNA Repair
TMP195 (TFMO 2) 是一种选择性 IIa 类组蛋白脱乙酰酶 (HDAC) 抑制剂。对 HDAC4、HDAC5、HDAC7,HDAC9的 Ki 值分别为59、60、26,5 nM。
T78269 Anti-Mouse PD-1 Antibody (RMP1-14)

PD-1/PD-L1 Apoptosis; Cell Cycle/Checkpoint; Immunology/Inflammation
RMP1-14 是一种 IgG1 样免疫球蛋白抗小鼠 PD-1 抗体,可阻断 PD-1/PD-L1 信号传导。
T41079 MMP13-IN-2

MMP13-IN-2

MMP13-IN-2 is a highly potent, selective, and orally active inhibitor of MMP-13. It demonstrates exceptional potency against MMP-13, with an IC50 value of 0.036 nM, and exhibits selectivities greater than 1,500-fold over MMP-1, 3, 7, 8, 9, 14, and TACE. Moreover, MMP13-IN-2 possesses the capability to effectively inhibit collagen release from cartilage in vitro. Consequently, MMP13-IN-2 holds great potential for advancing research on collagenase-related diseases.
T76244 Amp1EP9

Amp1EP9为一抗菌肽,作为开发有效无毒抗菌活性分子的强大工具,具备针对多重耐药细菌感染进行研究的潜力。
T83487 [Pmp1,Tyr(OEt)2] AVP

[Pmp1,Tyr(OEt)2] AVP为环状加压素(AVP)的线性拮抗剂,具备相似结构。
T80282 cPcAMP1/26

cPcAMP1/26 是一款抗菌肽,能高效清除A.Hydrophila及金黄色葡萄球菌 (S. aureus)。该化合物通过诱导细菌质膜去极化作用并提升细胞内ROS水平,展示其抗菌机制。
T78775 MMP13-IN-5

MMP Proteases/Proteasome
MMP13-IN-5 (compound 13m) 作为具有针对性的MMP-2/MMP-13 抑制剂,显示出高效的抑制活性(IC50=3.6 μM/14.6 μM),适用于骨关节炎疼痛的研究。
T78774 MMP13-IN-4

MMP Proteases/Proteasome
MMP13-IN-4(compound 13)作为MMP-13抑制剂,具备强效性和选择性,其IC50值为14.6 μM,可用于骨关节炎疼痛的研究。
T72306 Mycobacterial Zmp1-IN-1

Mycobacterial Zmp1-IN-1 是一种分枝杆菌锌金属蛋白酶-1(Zmp1)抑制剂。Mycobacterial Zmp1-IN-1 对 MtbH37Ra 具有剂量依赖性抑制的抗分枝杆菌活性。Mycobacterial Zmp1-IN-1 可用于结核病 (TB) 的研究。
T80336 DFTamP1

DFTamP1为抗菌肽,针对金黄色葡萄球菌USA300表现出活性,其最小抑菌浓度(MIC)为3.1 μM。
T82063 Integrin signaling inhibitor, mP13

Integrinsignaling inhibitor, mP13 是抑制整合素信号传导,阻止内向外和外向内信号传递,涉及纤维蛋白原结合、血小板粘附及凝块收缩的化合物。

化合物

Polybia-MP1
Cat.No: T76653
Synonym:
Target:
Anti-Mouse GM-CSF Antibody (MP1-22E9)
Cat.No: T80585
Synonym:
Target: c-Fms
BC-1485
Cat.No: T69977
Synonym:
Target:
MP-1
Cat.No: T71901
Synonym:
Target:
MMP13-IN-3
Cat.No: T16124
Synonym:
Target: MMP
TMP195
Cat.No: T3983
Synonym: TFMO 2,TMP 195
Target: HDAC
Anti-Mouse PD-1 Antibody (RMP1-14)
Cat.No: T78269
Synonym:
Target: PD-1/PD-L1
MMP13-IN-2
Cat.No: T41079
Synonym: MMP13-IN-2
Target:
Amp1EP9
Cat.No: T76244
Synonym:
Target:
[Pmp1,Tyr(OEt)2] AVP
Cat.No: T83487
Synonym:
Target:
cPcAMP1/26
Cat.No: T80282
Synonym:
Target:
MMP13-IN-5
Cat.No: T78775
Synonym:
Target: MMP
MMP13-IN-4
Cat.No: T78774
Synonym:
Target: MMP
Mycobacterial Zmp1-IN-1
Cat.No: T72306
Synonym:
Target:
DFTamP1
Cat.No: T80336
Synonym:
Target:
Integrin signaling inhibitor, mP13
Cat.No: T82063
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPJ-01378 Mp1 Protein, Human, Recombinant (His)

Mitogen-Activated Protein Kinase Kinase 1-Interacti...

Human E. coli
Mitogen-Activated Protein Kinase Scaffold Protein 1 (MAPKSP1) was identified as an interacting protein that belongs to the LAMTOR3 family. MAPKSP1 restricted to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. MAPKSP1 interacts with MAP2K1/MEK1 and MAPK2 and enhances the activation of MAPK2, and thus is thought to function as an adaptor to enhance the eff...
TMPY-01253 LAMP1 Protein, Human, Recombinant (His)

CD107a,lysosomal-associated membrane protein 1<...

Human HEK293 Cells
LAMP1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.8 kDa and the accession number is A0A024RDY3.
TMPY-01461 EMAP-II/AIMP1 Protein, Human, Recombinant (His)

SCYE1,p43,EMAPII,aminoacyl tRNA synthetase comp...

Human E. coli
EMAP-II/AIMP1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 35 kDa and the accession number is Q12904-1.
TMPH-00543 Epstein-Barr virus (strain Raji) LMP1 Protein (His & SUMO)

EBV E. coli
Epstein-Barr virus (strain Raji) LMP1 Protein (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 37.0 kDa and the accession number is P13198.
TMPY-04139 MCEMP1 Protein, Human, Recombinant (mFc)

C19orf59,mast cell-expressed membrane protein 1...

Human HEK293 Cells
MCEMP1 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 36 kDa and the accession number is A0A384NYE9.
TMPY-02916 LAMP1 Protein, Rat, Recombinant (hFc)

lysosomal-associated membrane protein 1

Rat HEK293 Cells
LAMP1 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65.1 kDa and the accession number is P14562.
TMPY-03015 EMAP-II/AIMP1 Protein, Mouse, Recombinant

AIMP1,p43,Scye1,EMAPII,aminoacyl ...

Mouse E. coli
EMAP-II/AIMP1 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 18 kDa and the accession number is Q62386.
TMPH-01226 CRMP1 Protein, Human, Recombinant

ULIP3,Collapsin response mediator protein 1,CRM...

Human E. coli
Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance. During the axon guidance process, acts downstream of SEMA3A to promote FLNA dissociation from F-actin which results in the rearrangement of the actin cytoskeleton and the collapse of the growth cone. Involved in invasive growth and cell migration. May participate in cytokinesis. CRMP1 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted mole...
TMPY-02010 DMP1 Protein, Human, Recombinant (His)

ARHR,dentin matrix acidic phosphoprotein 1,ARHP,D

Human HEK293 Cells
Dentin matrix acidic phosphoprotein (DMP1) is an extracellular matrix protein and a member of the small integrin binding ligand N-linked glycoprotein family. This protein, which is critical for proper mineralization of bone and dentin, is present in diverse cells of bone and tooth tissues. DMP1 contains a large number of acidic domains, multiple phosphorylation sites, a functional arg-gly-asp cell attachment sequence, and a DNA binding domain. In undifferentiated osteoblasts it is primarily a nu...
TMPH-00540 Epstein-Barr virus (strain GD1) LMP1 Protein (His)

EBV P. pastoris (Yeast)
Acts as a CD40 functional homolog to prevent apoptosis of infected B-lymphocytes and drive their proliferation. Functions as a constitutively active tumor necrosis factor receptor that induces the activation of several signaling pathways, including those of the NF-kappa-B family. LMP1 signaling leads to up-regulation of antiapoptotic proteins and provide growth signals in latently infected cells. Interacts with host UBE2I and subsequently affects the sumoylation state of several cellular protein...
TMPH-01076 CEMP1 Protein, Human, Recombinant (His)

Cementoblastoma-derived protein 1,Cementum protein ...

Human P. pastoris (Yeast)
May play a role in development of the periodontium which surrounds and supports the teeth by promoting the differentiation of multi-potent cells from the periodontal ligament into cementoblasts to form the cementum. Binds hydroxyapatite and may promote the biomineralization of the cementum. Also promotes cell proliferation. CEMP1 Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 28.0 kDa and the accession number is Q6PRD7.
TMPH-00541 Epstein-Barr virus (strain AG876) LMP1 Protein (His & Myc)

EBV E. coli
Acts as a CD40 functional homolog to prevent apoptosis of infected B-lymphocytes and drive their proliferation. Functions as a constitutively active tumor necrosis factor receptor that induces the activation of several signaling pathways, including those of the NF-kappa-B family. LMP1 signaling leads to up-regulation of antiapoptotic proteins and provide growth signals in latently infected cells. Interacts with host UBE2I and subsequently affects the sumoylation state of several cellular protein...
TMPK-01082 EFEMP1 Protein, Mouse, Recombinant (His)

EFEMP1,MTLV,MGC111

Mouse HEK293 Cells
Transversalis fascia EFEMP1, TIMP3 and ELN expressions were decreased, but MMP9 expression was increased in IH patients compared with controls. In IH patients, EFEMP1 was not correlated with TIMP3, but positively correlated with ELN and negatively correlated with MMP9; TIMP3 negatively correlated with MMP9, but positively correlated with ELN.In addition, EFEMP1 suppressed L929 cell migration and invasion. EFEMP1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with N-His ...
TMPK-01165 MCEMP1 Protein, Mouse, Recombinant (hFc)

MGC132456,C19orf59,MCEMP1

Mouse HEK293 Cells
A cecal ligation and puncture-induced sepsis mouse model was established to determine the expression of mast cell expression membrane protein 1 (MCEMP1). MCEMP1 in T lymphocytes isolated from sepsis mice were up- or downregulated by exogenous transfection in an attempt to investigate their effects on the release of inflammatory factors, the expression of immunoglobulins, the activity of T cell subsets and natural killer (NK) cells, as well as T lymphocyte apoptosis.
TMPY-05194 Rift Valley fever virus (RVFV) (strain MP12) glycoprotein/G2 Protein (His)

RVFV Baculovirus Insect Cells
Rift Valley fever virus (RVFV) (strain MP12) glycoprotein/G2 Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 50.1 kDa and the accession number is A2T077.
TMPH-00542 Epstein-Barr virus (strain Raji) LMP1 Protein (His)

EBV P. pastoris (Yeast)
Acts as a CD40 functional homolog to prevent apoptosis of infected B-lymphocytes and drive their proliferation. Functions as a constitutively active tumor necrosis factor receptor that induces the activation of several signaling pathways, including those of the NF-kappa-B family. LMP1 signaling leads to up-regulation of antiapoptotic proteins and provide growth signals in latently infected cells. Interacts with host UBE2I and subsequently affects the sumoylation state of several cellular protein...
TMPK-00867 EMAP-II/AIMP1 Protein, Mouse, Recombinant (His)

p43,SCYE1,HLD3,EMAP-II,AIMP1,EMAP...

Mouse E. coli
The potent antiangiogenic and proinflammatory protein Endothelial Monocyte Activating Polypeptide II (EMAP II) has been described as a mediator of pulmonary vascular and alveolar formation and its expression is inversely related to the periods of vascularization and alveolarization in the developing lung. Hence the study of EMAP II could play a vital role in studying and devising appropriate therapeutics for diseases of aberrant lung development, such as BPD.
TMPK-00946 EFEMP1 Protein, Human, Recombinant (His)

MLVT,S1-5,Fibulin 3,FBNL,fibrillin-like,MGC1

Human HEK293 Cells
Transversalis fascia EFEMP1, TIMP3 and ELN expressions were decreased, but MMP9 expression was increased in IH patients compared with controls. In IH patients, EFEMP1 was not correlated with TIMP3, but positively correlated with ELN and negatively correlated with MMP9; TIMP3 negatively correlated with MMP9, but positively correlated with ELN.In addition, EFEMP1 suppressed L929 cell migration and invasion. EFEMP1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with N-His ...
TMPJ-00264 LAMP1 Protein, Human, Recombinant (hFc)

LAMP-1,CD107a,Lysosome-Associated...

Human HEK293 Cells
Lysosome-Associated Membrane Glycoprotein 1 (LAMP1) is a single-pass type I membrane protein belonging to the LAMP family. LAMP1 is expressed largely in the endosome-lysosome membranes of cells.It shuttles between lysosomes, endosomes, and the plasma membrane. LAMP1 functions to present carbohydrate ligands to selectins and it has also been implicated in tumor cell metastasis. It has been proposed LAMP1 can be used as a therapeutic agent for certain cancers, as well as a marker for lysosomal sto...
TMPY-05175 Rift Valley fever virus (RVFV) (strain MP12) glycoprotein/G1 Protein (His)

RVFV Baculovirus Insect Cells
Rift Valley fever virus (RVFV) (strain MP12) glycoprotein/G1 Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 47.8 kDa and the accession number is A2T077.
TMPJ-00837 LAMP1 Protein, Mouse, Recombinant (His)

Lysosomal membrane glycoprotein A,CD107a,LAMP

Mouse HEK293 Cells
Lysosomal associated membrane protein 1 (LAMP1) is an approximately 120 kDa transmembrane glycoprotein that is a major protein component of lysosomal membranes. Mature mouse LAMP1 consists of a 346 amino acid (aa) intralumenal domain (ECD), a 24 aa transmembrane segment, and a 12 aa cytoplasmic tail. Its lumenal domain is organized into two heavily N-glycosylated regions separated by a Ser/Pro-rich linker that carries a minor amount of O-linked glycosylation. Within the lumenal domain, mouse LAM...
TMPY-02252 LAMTOR2 Protein, Human, Recombinant (His)

Ragulator2,p14,MAPBPIP,MAPKSP1AP,RP1

Human E. coli
Ragulator complex protein LAMTOR2, also known as Endosomal adaptor protein p14, Late endosomal/lysosomal Mp1-interacting protein, Late endosomal/lysosomal adaptor and MAPK and MTOR activator 2, Mitogen-activated protein-binding protein-interacting protein, Roadblock domain-containing protein 3, LAMTOR2, MAPBPIP, and ROBLD3, is a protein which belongs to the GAMAD family. LAMTOR2 / ROBLD3 is a regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factor...

重组蛋白

Mp1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01378
Species: Human
Expression System: E. coli
LAMP1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01253
Species: Human
Expression System: HEK293 Cells
EMAP-II/AIMP1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01461
Species: Human
Expression System: E. coli
Epstein-Barr virus (strain Raji) LMP1 Protein (His & SUMO)
Cat.No: TMPH-00543
Species: EBV
Expression System: E. coli
MCEMP1 Protein, Human, Recombinant (mFc)
Cat.No: TMPY-04139
Species: Human
Expression System: HEK293 Cells
LAMP1 Protein, Rat, Recombinant (hFc)
Cat.No: TMPY-02916
Species: Rat
Expression System: HEK293 Cells
EMAP-II/AIMP1 Protein, Mouse, Recombinant
Cat.No: TMPY-03015
Species: Mouse
Expression System: E. coli
CRMP1 Protein, Human, Recombinant
Cat.No: TMPH-01226
Species: Human
Expression System: E. coli
DMP1 Protein, Human, Recombinant (His)
Cat.No: TMPY-02010
Species: Human
Expression System: HEK293 Cells
Epstein-Barr virus (strain GD1) LMP1 Protein (His)
Cat.No: TMPH-00540
Species: EBV
Expression System: P. pastoris (Yeast)
CEMP1 Protein, Human, Recombinant (His)
Cat.No: TMPH-01076
Species: Human
Expression System: P. pastoris (Yeast)
Epstein-Barr virus (strain AG876) LMP1 Protein (His & Myc)
Cat.No: TMPH-00541
Species: EBV
Expression System: E. coli
EFEMP1 Protein, Mouse, Recombinant (His)
Cat.No: TMPK-01082
Species: Mouse
Expression System: HEK293 Cells
MCEMP1 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPK-01165
Species: Mouse
Expression System: HEK293 Cells
Rift Valley fever virus (RVFV) (strain MP12) glycoprotein/G2 Protein (His)
Cat.No: TMPY-05194
Species: RVFV
Expression System: Baculovirus Insect Cells
Epstein-Barr virus (strain Raji) LMP1 Protein (His)
Cat.No: TMPH-00542
Species: EBV
Expression System: P. pastoris (Yeast)
EMAP-II/AIMP1 Protein, Mouse, Recombinant (His)
Cat.No: TMPK-00867
Species: Mouse
Expression System: E. coli
EFEMP1 Protein, Human, Recombinant (His)
Cat.No: TMPK-00946
Species: Human
Expression System: HEK293 Cells
LAMP1 Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-00264
Species: Human
Expression System: HEK293 Cells
Rift Valley fever virus (RVFV) (strain MP12) glycoprotein/G1 Protein (His)
Cat.No: TMPY-05175
Species: RVFV
Expression System: Baculovirus Insect Cells
LAMP1 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00837
Species: Mouse
Expression System: HEK293 Cells
LAMTOR2 Protein, Human, Recombinant (His)
Cat.No: TMPY-02252
Species: Human
Expression System: E. coli
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