Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T20993 |
Memantine
|
Others | Others |
Memantine 是口服具有活性的、非竞争性的N-甲基-D-天冬氨酸受体拮抗剂,可用于研究中重度阿尔茨海默病。 | |||
T1443 |
Memantine hydrochloride
3,5-二甲基金刚胺盐酸盐,盐酸美金刚,Namenda,Memantine HCl,D-145 (hydrochloride) |
P450; GluR; NMDAR; Autophagy; iGluR | Autophagy; Membrane transporter/Ion channel; Metabolism; Neuroscience |
Memantine hydrochloride (Memantine HCl) 是一种具有一些多巴胺能作用的金刚烷胺衍生物,是一种温和的 NMDA 受体非竞争性拮抗剂,能够抑制 CYP2B6 和 CYP2D6。它可作为抗帕金森剂。 | |||
T0535 |
Memantine Related Compound B
美金刚杂质B,3,5-Dimethyl-1-adamantanol |
Others | Others |
Memantine Related Compound B (3,5-Dimethyl-1-adamantanol) 是Memantine 的杂质。 | |||
T2556 |
Nandrolone decanoate
癸酸诺龙,19-Nortestosterone decanoate |
Others; HIV Protease | Microbiology/Virology; Others; Proteases/Proteasome |
Nandrolone decanoate (19-Nortestosterone decanoate) 是一种合成代谢雄激素,通过涉及谷氨酸诱导的 N-甲基-D-天冬氨酸受体过度兴奋的机制诱导攻击性行为表征。 | |||
T39120 |
Fluoroethylnormemantine
|
||
Fluoroethylnormemantine, a derivative of Memantine, acts as an N-methyl-D-aspartate (NMDA) receptor antagonist. It can function as a positron emission tomography (PET) tracer, known as [18F]-fluoroethylnormemantine. This compound displays anti-amnesic, neuroprotective, antidepressant-like, and fear-attenuating properties. | |||
T39119 |
Fluoroethylnormemantine hydrochloride
|
||
Fluoroethylnormemantine hydrochloride, a Memantine derivative, functions as an antagonist for the N-methyl-D-aspartate (NMDA) receptor. It can also serve as a positron emission tomography (PET) tracer, specifically as [18F]-Fluoroethylnormemantine hydrochloride. Notably, this compound displays a range of effects, including anti-amnesic, neuroprotective, antidepressant-like, and fear-attenuating properties. | |||
T69814 |
Neramexane Free Base
|
||
Neramexane Free Base is a drug related to memantine, which acts as an NMDA antagonist and has neuroprotective effects. It is being developed for various possible applications, including treatment of tinnitus, Alzheimer's disease, drug addiction and as an analgesic. | |||
T83187 | AChE-IN-41 | ||
AChE-IN-41(Compound 2)是一种加兰他敏-美金刚杂交体化合物,能够抑制胆碱酯酶。在体外,该化合物展现出较高的血浆稳定性和良好的微粒体稳定性;而在体内,则具有较短的半衰期和较快的清除速率。 |