Cat. No. | Product Name | Target | Signaling Pathways |
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T60509 |
Maprotiline
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Maprotiline 能够抑制细胞的增殖和转移,具有抗癌作用。 Maprotiline 通过靶向 ERK 信号通路和 CRABP1 诱导癌细胞凋亡。 Maprotiline 是一种高度选择性的去甲肾上腺素再摄取阻滞剂,具有有效的抗抑郁作用 [1][2]。 | |||
T0172 |
Maprotiline hydrochloride
Maprotiline HCl,盐酸马普替林,Psymion,Deprilept,Ludiomil |
5-HT Receptor; Adrenergic Receptor; AChR; Norepinephrine; Autophagy; Histamine Receptor | Autophagy; GPCR/G Protein; Immunology/Inflammation; Neuroscience |
Maprotiline hydrochloride (Psymion) 是一种桥环四环类抗抑郁药,是去甲肾上腺素重吸收抑制剂。 | |||
T70960 |
Maprotiline-d3 hydrochloride
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Maprotiline-d3 is intended for use as an internal standard for the quantification of maprotiline by GC- or LC-MS. Maprotiline is a tricyclic antidepressant. It binds to the norepinephrine transporter (NET) and is selective for NET over the serotonin and dopamine transporters. Maprotiline also binds to the serotonin (5-HT) receptor subtype 5-HT2A, as well as histamine H1, muscarinic acetylcholine, α1-adrenergic, and dopamine D2 receptors. In vivo, maprotiline inhibits norepinephrine reuptake in r... | |||
T70958 | Dov-Val-Dil-OH TFA | ||
Dov-Val-Dil-OH is a useful chemical intermediate for synthesis of auristatin-related compounds, such as Monomethyl auristatin E (MMAE), Auristatins are antimitotic agents which inhibits cell division by blocking the polymerisation of tubulin. | |||
T24852 |
Tamitinol
EMD 21 657,Emd21657,Emd 21657,Emd-21657 |
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Tamitinol is a neurotropic drug. It has been found to help symptoms of obsessive rumination in conjunction with maprotiline. | |||
T25698 |
Levoprotiline
Levoprotilinum |
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Levoprotiline 一种抗抑郁的化合物,它是 Oxaprotiline 的 R-(-)对映体,作用与 Oxaprotiline 相当,并且作用起效潜伏期较短。它是第二代抗抑郁药马普替林的继任者。 |