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Search Results for " mdh2 "

Targets Recommended: Apoptosis Dehydrogenase HIF/HIF Prolyl-Hydroxylase HIF

2

抑制剂 & 化合物

4

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T3494	LW6 HIF-1α inhibitor,CAY10585,LW8	Apoptosis; Dehydrogenase; HIF/HIF Prolyl-Hydroxylase; HIF	Angiogenesis; Apoptosis; Chromatin/Epigenetic; Metabolism
	LW6 (HIF-1α inhibitor) 是一种新型 HIF-1抑制剂，IC50值为 4.4 μM。它降低 HIF-1α蛋白表达，但不影响 HIF-1β 表达。
T76118	Malate dehydrogenase
	Malate dehydrogenase 催化草酰乙酸盐和苹果酸盐的相互转化，与二核苷酸辅酶的氧化/还原相关。

化合物

Cat.No: T3494

Synonym: HIF-1α inhibitor,CAY10585,LW8

Target: Apoptosis, Dehydrogenase, HIF/HIF Prolyl-Hydroxylase, HIF

Malate dehydrogenase

Cat.No: T76118

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-00956	MDH2 Protein, Human, Recombinant (His) MDH2,Malate dehydrogenase,mitochondrial	Human	HEK293 Cells
	Malate dehydrogenase, mitochondrial is a 338 amino acids protein that belongs to the LDH/MDH superfamily. MDH type 1 family. MDH2 catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. MDH2 is localized to the mitochondria and takes part in the malate-aspartate shuttle that functions in the metabolic coordination between cytosol and mitochondria. MDH2 is highly expressed in the adrenal system, small intestine, heart and panc...
TMPJ-00801	UQCRH Protein, Human, Recombinant (GST) Complex III subunit 6,Ubiquinol-cytochrome c reductase compl...	Human	E. coli
	Cytochrome b-c1 complex subunit 6, mitochondrial (UQCRH) belongs to the UQCRH/QCR6 family, it is a subunit of the respiratory chain protein Ubiquinol Cytochrome c Reductase. This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. UQCRH may mediate formation of the complex between cytochromes c and c1. It may mediate formation of the complex between cytochromes c and c1.
TMPY-04764	PCK2 Protein, Human, Recombinant (His & GST) PEPCK-M,PEPCK2,PEPCK,phosphoenolpyruvate carboxykin...	Human	Baculovirus Insect Cells
	PCK2 promotes tumor initiation by lowering acetyl-CoA level through reducing the mitochondrial tricarboxylic acid (TCA) cycle. The levels of phosphoenolpyruvate carboxykinase isoform 2 (PCK2) are critical for the metabolic switch and the maintenance of TICs in prostate cancer. PCK2 is a potential therapeutic target for aggressive prostate tumors.
TMPY-01344	MAP1D Protein, Human, Recombinant (His) MetAP 1D,Metap1l,MAP 1D,methionyl aminopeptidase type 1D (mi...	Human	Baculovirus Insect Cells
	Methionine aminopeptidase 1D, also known as MAP1D, is a member of the peptidase M24A family. N-terminal methionine removal is an important cellular process required for proper biological activity, subcellular localization, and eventual degradation of many proteins. The enzymes that catalyze this reaction are called Methionine aminopeptidases (MAPs). MAP1D is overexpressed in colon cancer cell lines and colon tumors as compared to normal tissues (at protein level). Downregulation of MAP1D express...

重组蛋白

MDH2 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00956

Species: Human

Expression System: HEK293 Cells

UQCRH Protein, Human, Recombinant (GST)

Cat.No: TMPJ-00801

Species: Human

Expression System: E. coli

PCK2 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-04764

Species: Human

Expression System: Baculovirus Insect Cells

MAP1D Protein, Human, Recombinant (His)

Cat.No: TMPY-01344

Species: Human

Expression System: Baculovirus Insect Cells

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