Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T4569 |
Lucanthone
Lucantona,Lucanthonum,硫坎酮,硫蒽酮 |
DNA/RNA Synthesis; Autophagy | Autophagy; Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
Lucanthone (Lucanthonum) 是一种 Apurinic 核酸内切酶-1 的抑制剂。 | |||
T4569L |
Lucanthone hydrochloride
Lucanthone HCl |
||
Lucanthone hydrochloride is a novel acridine derivative which supresses autophagic degradation and triggers apoptosis in colon cancer cells. | |||
T32917 | Lucanthone N-oxide | ||
Lucanthone N-oxide is a bioactive chemical. | |||
T32918 |
Lucanthone N-oxide monomethanesulfonate
|
||
Lucanthone N-oxide monomethanesulfonate is a bioactive chemical. | |||
T15507 |
Hycanthone
Etrenol(mesylate),Win 249-33,海恩酮 |
DNA/RNA Synthesis; Topoisomerase; Parasite | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology |
Hycanthone (Etrenol(mesylate)) 是 Lucanthone 的生物活性代谢产物,是一种抗血吸虫病药。它是一个噻吨酮类 DNA 嵌入剂,可抑制 RNA 合成以及 DNA 拓扑异构酶 I 和 II。它通过直接蛋白质结合来抑制核酸生物合成并抑制嘌呤内切核酸酶1,KD 为 10 nM。 |