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Cat. No. Product Name Target Signaling Pathways
T1415 Gemfibrozil

吉非罗齐,CI-719,Jezil,Decrelip,Lopid

P450; Adrenergic Receptor; PPAR DNA Damage/DNA Repair; GPCR/G Protein; Metabolism; Neuroscience
Gemfibrozil (CI-719) 是一种PPAR-α激活剂,可作为降脂药。它也是P450非选择性抑制剂,对 CYP2C9、2C19、2C8 和 1A2 的Ki 值分别为 5.8、24、69 和 82 μM。
T0182 Clopidogrel

(S)-Clopidogrel,SR-25990C,氯吡格雷

P2Y Receptor GPCR/G Protein; Neuroscience
Clopidogrel (SR-25990C) 是一种 P2Y12 受体拮抗剂,可降低血小板聚集,用于抑制冠状动脉疾病、周围血管疾病和脑血管疾病中的血凝块。
T4190 Ticlopidine

PCR 5332,Ticlid,噻氯匹定

ATPase; Adiponectin receptor GPCR/G Protein; Membrane transporter/Ion channel
Ticlopidine (PCR 5332) 是抗血栓前药。它是CYP2C19人肝细胞色素的抑制剂,抑制 CYP2C9 及 CYP3A4。他是变构CD39的非竞争性抑制剂,能够阻断 NTPDase 同工酶,对NTPDase2和NTPDase3的IC50分别为 170 µM 和 149 µM。
T0182L Clopidogrel hydrogen sulfate

硫酸氢氯吡格雷,(S)-(+)-Clopidogrel hydrogen sulfate,(S)-(+)-Clopidogrel bisulfate,SR-25990C,Clopidogrel,硫酸氯吡格雷

P450; P2Y Receptor GPCR/G Protein; Metabolism; Neuroscience
Clopidogrel hydrogen sulfate ((S)-(+)-Clopidogrel bisulfate) 是一种抗血小板药物,可防止血栓形成。它抑制 CYP2B6和 CYP2C19,IC50分别为 18.2 和 524 nM。 它是一种选择性的高亲和力 P2Y12 受体拮抗剂,可抑制纤维蛋白原与血小板的结合以及血小板的粘附和聚集。
T0182L2 (±) Clopidogrel hydrogen sulfate

硫酸氢氯吡格雷,Plavix,Clopidogrel hydrogen sulfate,Iscover

P2Y Receptor GPCR/G Protein; Neuroscience
(±) Clopidogrel hydrogen sulfate (Iscover) 是一种在药理学和结构上类似于ticlopidine 的抗血小板药物,用于抑制脑血管疾病、外周血管疾病和冠状动脉疾病等各种疾病中的血栓。
T0362 Ticlopidine hydrochloride

Ticlodone,Ticlopidine HCl,Ticlodix,盐酸噻氯匹定

Adenosine Receptor GPCR/G Protein; Neuroscience
Ticlopidine hydrochloride (Ticlodix) 是一种 ADP 受体抑制剂,对血小板凝集的IC50为2 μM。
T1044 Clopidol

氯吡多,氯羟吡啶,WR-61112

Antibiotic; Parasite Microbiology/Virology
Clopidol (WR-61112) 是一种用于家禽的抗球虫剂。它可抑制艾美耳球虫卵囊的孢子形成。
T71254 Clopidogrel HCl

Clopidogrel HCl is the salt form of Clopidogrel (free base), an inhibitor of ADP-induced platelet aggregation acting by direct inhibition of adenosine diphosphate (ADP) binding to its receptor and of the subsequent ADP-mediated activation of the glycoprotein GPIIb/IIIa complex.
T5501 Clopidogrel thiolactone

2-oxoclopidogrel

P2Y Receptor GPCR/G Protein; Neuroscience
Clopidogrel thiolactone (2-oxoclopidogrel) 是一种有效的 P2Y12 受体抑制剂, 是一种有效的抗血小板聚集化合物。Clopidogrel thiolactone是Clopidogrel第一次氧化活化产生的活性代谢中间体。
T36222 2-oxo Clopidogrel

2-oxo Clopidogrel is an intermediary metabolite of clopidogrel . Clopidogrel is a prodrug that is converted to its active metabolite via two sequential oxidative steps. The first step leads to formation of 2-oxo clopidogrel, followed by conversion to the active metabolite, which binds specifically and irreversibly to the platelet P2Y12 purinergic receptor, inhibiting ADP-mediated platelet activation and aggregation.
T35431 (±)-Clopidogrel (hydrochloride)

Clopidogrel is an antithrombic compound whose active metabolite is a selective, irreversible antagonist of the platelet purinergic P2Y12 receptor (IC50 = 100 nM). Clopidogrel inhibits ADP-induced platelet aggregation ex vivo and functions as a prodrug whereupon biotransformation to its active metabolite via CYP2C19 in the liver enables its anti-aggregating activity. Marketed under the name Plavix , clopidogrel in combination with aspirin has been shown to be beneficial in the prevention of vascu...
T38506 cis-Clopidogrel-MP derivative

cis-Clopidogrel-MP derivative,Clopidogrel-MP-AM

cis-Clopidogrel-MP derivative, also known as Clopidogrel-MP-AM, is a 3’-methoxyacetophenone derivative of Clopidogrel active metabolite. This compound is an orally-active platelet inhibitor specifically targeting the P2Y12 receptor.
T125846 Clopidogrel Related Compound B

Clopidogrel Related Compound B 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T125846,CAS号为 144750-52-7。
T30193 Atelopidtoxin

Atelopidtoxin is a biochemical.
T126236 Clopidogrel Related Compound C

Clopidogrel Related Compound C 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T126236,CAS号为 120202-71-3。
T125853 Clopidogrel Related Compound A

Clopidogrel Related Compound A 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T125853,CAS号为 144457-28-3。
T36112 Clopidogrel Carboxylic Acid (hydrochloride)

Clopidogrel is an antithrombic compound whose active metabolite is a selective, irreversible antagonist of the platelet purinergic P2Y12 receptor (IC50 = 100 nM). Clopidogrel inhibits ADP-induced platelet aggregation ex vivo and functions as a prodrug whereupon biotransformation to its active thiol metabolite via CYP2C19 in the liver enables its anti-aggregating activity. An estimated 15% of administered clopidogrel is metabolized by CYP2C19 to the thiol metabolite. Clopidogrel carboxylic acid i...

化合物

Gemfibrozil
Cat.No: T1415
Synonym: 吉非罗齐,CI-719,Jezil,Decrelip,Lopid
Target: P450, Adrenergic Receptor, PPAR
Clopidogrel
Cat.No: T0182
Synonym: (S)-Clopidogrel,SR-25990C,氯吡格雷
Target: P2Y Receptor
Ticlopidine
Cat.No: T4190
Synonym: PCR 5332,Ticlid,噻氯匹定
Target: ATPase, Adiponectin receptor
Clopidogrel hydrogen sulfate
Cat.No: T0182L
Synonym: 硫酸氢氯吡格雷,(S)-(+)-Clopidogrel hydrogen sulfate,(S)-(+)-Clopidogrel bisulfate,SR-25990C,Clopidogrel,硫酸氯吡格雷
Target: P450, P2Y Receptor
(±) Clopidogrel hydrogen sulfate
Cat.No: T0182L2
Synonym: 硫酸氢氯吡格雷,Plavix,Clopidogrel hydrogen sulfate,Iscover
Target: P2Y Receptor
Ticlopidine hydrochloride
Cat.No: T0362
Synonym: Ticlodone,Ticlopidine HCl,Ticlodix,盐酸噻氯匹定
Target: Adenosine Receptor
Clopidol
Cat.No: T1044
Synonym: 氯吡多,氯羟吡啶,WR-61112
Target: Antibiotic, Parasite
Clopidogrel HCl
Cat.No: T71254
Synonym:
Target:
Clopidogrel thiolactone
Cat.No: T5501
Synonym: 2-oxoclopidogrel
Target: P2Y Receptor
2-oxo Clopidogrel
Cat.No: T36222
Synonym:
Target:
(±)-Clopidogrel (hydrochloride)
Cat.No: T35431
Synonym:
Target:
cis-Clopidogrel-MP derivative
Cat.No: T38506
Synonym: cis-Clopidogrel-MP derivative,Clopidogrel-MP-AM
Target:
Clopidogrel Related Compound B
Cat.No: T125846
Synonym:
Target:
Atelopidtoxin
Cat.No: T30193
Synonym:
Target:
Clopidogrel Related Compound C
Cat.No: T126236
Synonym:
Target:
Clopidogrel Related Compound A
Cat.No: T125853
Synonym:
Target:
Clopidogrel Carboxylic Acid (hydrochloride)
Cat.No: T36112
Synonym:
Target:
TargetMol Loading
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