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6

抑制剂 & 化合物

9

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T24423 LY5

LY 5,LY-5

LY5 is an inhibitor of STAT3 that acts by inhibiting cell viability, cell migration, and angiogenesis in medulloblastoma cells.
T15821 LY518674

LY-674

PPAR DNA Damage/DNA Repair; Metabolism
LY518674 (LY-674) 是一种高效、选择性的 PPARα 激动剂,对人 PPARα 作用的 EC50 值为 42 nM。LY518674 能降低甘油三酸酯,增加 HDL-C,可用于研究动脉粥样硬化。
T25765 LY52

LY-52,LY 52

LY52 is a matrix metalloproteinase-2 inhibitor. It acts by suppressing tumor invasion and metastasis.
T27961 LY593093

LY 593093,LY-593093

LY593093 is a selective partial orthosteric agonist of M1 muscarinic acetylcholine receptor.
T27959 LY503430

LY-503430,LY 503430

LY503430 is a AMPA receptor potentiator with oral activity. LY503430 has both nootropic and neuroprotective effects, reducing brain damage caused by 6-hydroxydopamine or MPTP.
T39373 PNU-EDA-Gly5

PNU-EDA-Gly5

PNU-EDA-Gly5 is a DNA topoisomerase I inhibitor-based oligo-glycine linker-payload used for the synthesis of antibody-drug conjugates (ADCs). It consists of the DNA topoisomerase I inhibitor PNU-159682 and the linker EDA-Gly5.

化合物

LY5
Cat.No: T24423
Synonym: LY 5,LY-5
Target:
LY518674
Cat.No: T15821
Synonym: LY-674
Target: PPAR
LY52
Cat.No: T25765
Synonym: LY-52,LY 52
Target:
LY593093
Cat.No: T27961
Synonym: LY 593093,LY-593093
Target:
LY503430
Cat.No: T27959
Synonym: LY-503430,LY 503430
Target:
PNU-EDA-Gly5
Cat.No: T39373
Synonym: PNU-EDA-Gly5
Target:
Cat. No. Product Name Species Expression System
TMPY-05748 CD45 Protein, Human, Recombinant (aa 26-577, His)

L-CA,T200,LCA,B220,protein tyrosine phosphatase, receptor ty...

Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins d...
TMPY-05308 CD45 Protein, Human, Recombinant (aa 1-529, His)

GP180,B220,L-CA,protein tyrosine phosphatase, receptor type,...

Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins d...
TMPK-00423 CD45 Protein, Human, Recombinant (His & Avi)

CD45R,LY5,EC 3.1.3.48,B220,CD4

Human HEK293
PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) complex. CD45 ativates Lck by opposing the negative regulatory kinase Csk. Paradoxically, CD45 has also been implicated in suppressing TCR signaling by dephosphorylating the same signaling motifs within the TCR complex upon which Lck acts.
TMPK-00447 CD45 Protein, Human, Recombinant (aa 26-577, hFc)

CD45,CD45R,LCA,PTPRC,L-CA,T200,B220,GP180,...

Human HEK293
PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) complex. CD45 ativates Lck by opposing the negative regulatory kinase Csk. Paradoxically, CD45 has also been implicated in suppressing TCR signaling by dephosphorylating the same signaling motifs within the TCR complex upon which Lck acts.
TMPY-00711 CD45 Protein, Human, Recombinant (hFc)

GP180,L-CA,LY5,T200,protein tyrosine phosp...

Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins d...
TMPK-00424 CD45 Protein, Human, Recombinant (His & Avi), Biotinylated

LCA,LY5,EC 3.1.3.48,CD45,L-CA,T20...

Human HEK293
PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) complex. CD45 ativates Lck by opposing the negative regulatory kinase Csk. Paradoxically, CD45 has also been implicated in suppressing TCR signaling by dephosphorylating the same signaling motifs within the TCR complex upon which Lck acts.
TMPJ-00410 CD45R0 Protein, Human, Recombinant (His)

CD45 antigen,L-CA,protein tyrosine phosphatase, rec...

Human Human Cells
Protein tyrosine phosphatase, receptor type C (CD45), also known as PTPRC is a member of the protein tyrosine phosphatase (PTP) family which is known for its function to serve as signaling molecules and to regulate a variety of cellular processes such as cell proliferation, differentiation, mitotic cycle and oncogenic transformation. It is a variably glycosylated 180-220 kDa transmembrane protein that is abundantly expressed on all nucleated cells of hematopoietic origin. CD45 has several isofor...
TMPJ-00794 CD45 Protein, Mouse, Recombinant (His)

CD45,receptor-type tyrosine-protein phosphatase C,C...

Mouse Human Cells
Protein tyrosine phosphatase, receptor type C (CD45), also known as PTPRC is a member of the protein tyrosine phosphatase (PTP) family which is known for its function to serve as signaling molecules and to regulate a variety of cellular processes such as cell proliferation, differentiation, mitotic cycle and oncogenic transformation. It is a variably glycosylated 180-220 kDa transmembrane protein that is abundantly expressed on all nucleated cells of hematopoietic origin. CD45 has several isofor...
TMPJ-00808 CD45RA Protein, Human, Recombinant (His)

PTPRC,CD45R,CD45,LCA,protein tyrosine phos...

Human Human Cells
Protein tyrosine phosphatase, receptor type C (CD45), also known as PTPRC is a member of the protein tyrosine phosphatase (PTP) family which is known for its function to serve as signaling molecules and to regulate a variety of cellular processes such as cell proliferation, differentiation, mitotic cycle and oncogenic transformation. It is a variably glycosylated 180-220 kDa transmembrane protein that is abundantly expressed on all nucleated cells of hematopoietic origin. CD45 has several isofor...

重组蛋白

CD45 Protein, Human, Recombinant (aa 26-577, His)
Cat.No: TMPY-05748
Species: Human
Expression System: HEK293
CD45 Protein, Human, Recombinant (aa 1-529, His)
Cat.No: TMPY-05308
Species: Human
Expression System: HEK293
CD45 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00423
Species: Human
Expression System: HEK293
CD45 Protein, Human, Recombinant (aa 26-577, hFc)
Cat.No: TMPK-00447
Species: Human
Expression System: HEK293
CD45 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00711
Species: Human
Expression System: HEK293
CD45 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00424
Species: Human
Expression System: HEK293
CD45R0 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00410
Species: Human
Expression System: Human Cells
CD45 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00794
Species: Mouse
Expression System: Human Cells
CD45RA Protein, Human, Recombinant (His)
Cat.No: TMPJ-00808
Species: Human
Expression System: Human Cells
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