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Cat. No.	Product Name	Target	Signaling Pathways
T24271	KSP-IA KSP IA
	KSP-IA is a potent, specific, allosteric, and cell-active KSP inhibitor.
T32571	Larkspur alkaloid Bicoloridine
	Larkspur alkaloid is a bioactive chemical.
T39014	KSPWFTTL
	KSPWFTTL is an immunodominant epitope derived from the p15E transmembrane protein. It is Kb-restricted and can enhance the susceptibility of a tumor cell line to cytotoxic T lymphocytes targeting anti-AKR/Gross MuLV.
T2255	SB-743921 hydrochloride SB743921 HCl,SB743921	Kinesin; KSP	Cell Cycle/Checkpoint; Cytoskeletal Signaling
	SB-743921 hydrochloride (SB743921 HCl) 是一种有效的驱动蛋白纺锤体蛋白 KSP 抑制剂，Ki 值为 0.1 nM。
TQ0318	Filanesib ARRY-520,ARRY 520	KSP	Cell Cycle/Checkpoint
	Filanesib (ARRY 520) 是一种选择性的驱动蛋白纺锤体蛋白(KSP)的抑制剂(IC50 = 6 nM)，具有强大的抗增殖活性。
T2103	Ispinesib 伊匹尼塞,伊斯平斯,CK0238273,SB-715992	Apoptosis; Kinesin; KSP	Apoptosis; Cell Cycle/Checkpoint; Cytoskeletal Signaling
	Ispinesib (SB-715992) 是一种选择性可逆的驱动蛋白纺锤体蛋白抑制剂，具有抗肿瘤特性。
T6209	CW-069 CW069	Kinesin; Microtubule Associated	Cytoskeletal Signaling
	CW-069 是一种微管运动蛋白 HSET 的变构选择性抑制剂，IC50值为 75 μM，对 KSP 具有显着的特异性。
TQ0318L	ARRY 520 hydrochloride	KSP	Cell Cycle/Checkpoint
	ARRY 520 hydrochloride 是一种驱动蛋白纺锤体蛋白 (KSP) 抑制剂。它通过凋亡诱导细胞死亡，并具有有效的抗增殖活性。
T25418	Filanesib TFA Filanesib trifluoroacetic acid,ARRY-520 TFA,ARRY 520 TFA,ARRY520 TFA
	Filanesib (ARRY-520) targets the kinesin spindle protein (KSP) with potential antineoplastic activity. ARRY-520 specifically inhibits KSP (kinesin-5 or Eg5), resulting in activation of the spindle assembly checkpoint, induction of cell cycle arrest during
T28694	SB-743921 free base SB743921,SB-921,SB921,SB-743921,GSK-743921,GSK-921
	SB-743921, a kinesin spindle protein (KSP) inhibitor, is used potentially for the treatment of non-Hodgkin's lymphoma (NHL).
T68743	AZD4877 HCl
	AZD4877 is a synthetic kinesin spindle protein (KSP) inhibitor with potential antineoplastic activity. KSP inhibitor AZD4877 selectively inhibits microtubule motor protein KSP (also called kinesin-5 or Eg5), which may result in the inhibition of mitotic spindle assembly; activation of the spindle assembly checkpoint; induction of cell cycle arrest during the mitotic phase; and cell death in tumor cells that are actively dividing. Because KSP is not involved in postmitotic processes, such as neur...
T21321	MK-0731
	MK-0731, a synthetic small molecule with potential antineoplastic activity, selectively inhibits kinesin spindle protein (KSP), leading to the inhibition of mitotic spindle assembly, induction of cell cycle arrest during the mitotic phase and apoptosis in
T69415	CK0106023
	CK0106023 was specific inhibitor of KSP. In tumor-bearing mice, CK0106023 exhibited antitumor activity comparable to or exceeding that of paclitaxel and caused the formation of monopolar mitotic figures identical to those produced in cultured cells. KSP was most abundant in proliferating human tissues and was absent from cultured postmitotic neurons.
T36816	S-trityl-L-Cysteine STLC	Kinesin	Cytoskeletal Signaling
	S-Trityl-L-cysteine 是别构驱动蛋白Eg5的选择性抑制剂。rityl-L-cysteine 抑制基础 ATPase 活性的IC50为 1 μM，抑制微管激活的 ATPase 活性的IC50为 140 nM。S-Trityl-L-cysteine 显示出抗肿瘤活性。
T10373	(R)-Filanesib (R)-ARRY-520	Others	Others
	(R)-Filanesib is the R-enantiomer of ARRY-520. (R)-Filanesib is a synthetic kinesin spindle protein (KSP) inhibitor (IC50: 6 nM).
T81871	Mal-PEG8-Val-Ala-PAB-SB-743921
	Mal-PEG8-Val-Ala-PAB-SB-743921 (Compound D7) 是一种用于 ADC 的药物-Linker偶联物。由KSP抑制剂SB-743921和连接子组成，此合成物可应用于ADC合成过程。

化合物

Cat.No: T24271

Synonym: KSP IA

Larkspur alkaloid

Cat.No: T32571

Synonym: Bicoloridine

Cat.No: T39014

SB-743921 hydrochloride

Cat.No: T2255

Synonym: SB743921 HCl,SB743921

Target: Kinesin, KSP

Cat.No: TQ0318

Synonym: ARRY-520,ARRY 520

Target: KSP

Cat.No: T2103

Synonym: 伊匹尼塞,伊斯平斯,CK0238273,SB-715992

Target: Apoptosis, Kinesin, KSP

Cat.No: T6209

Synonym: CW069

Target: Kinesin, Microtubule Associated

ARRY 520 hydrochloride

Cat.No: TQ0318L

Target: KSP

Cat.No: T25418

Synonym: Filanesib trifluoroacetic acid,ARRY-520 TFA,ARRY 520 TFA,ARRY520 TFA

SB-743921 free base

Cat.No: T28694

Synonym: SB743921,SB-921,SB921,SB-743921,GSK-743921,GSK-921

Cat.No: T68743

Cat.No: T21321

Cat.No: T69415

S-trityl-L-Cysteine

Cat.No: T36816

Synonym: STLC

Target: Kinesin

Cat.No: T10373

Synonym: (R)-ARRY-520

Target: Others

Mal-PEG8-Val-Ala-PAB-SB-743921

Cat.No: T81871

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