Cat. No. | Product Name | Target | Signaling Pathways |
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T1056 |
Isoprenaline hydrochloride
NCI-c55630,Isoproterenol hydrochloride,Isoprenaline HCl,盐酸异丙肾上腺素 |
PI3K; Endogenous Metabolite; Adrenergic Receptor; PDE | GPCR/G Protein; Metabolism; Neuroscience; PI3K/Akt/mTOR signaling |
Isoprenaline hydrochloride (NCI-c55630) 是非选择性的β-肾上腺素能受体激动剂,有支气管扩张剂,外周血管扩张剂和心脏刺激活性。 | |||
T21411 |
Isoproterenol
Norisodrine,Isoprenaline,Novodrin,Isuprel,Medihaler-Iso |
Endogenous Metabolite; Adrenergic Receptor | GPCR/G Protein; Metabolism; Neuroscience |
Isoproterenol (Norisodrine) 是一种非选择性且具有口服活性的 β-肾上腺素受体激动剂。Isoproterenol 是有效的外周血管扩张剂和支气管扩张剂。Isoproterenol 可用于研究心动过缓和支气管哮喘,用于治疗心脏传导阻滞、心动过缓。 | |||
T32697 |
Levisoprenaline
(R)-Isoprenaline,Levisoprenalina,BRN-3203136,BRN 3203136,Proternol L |
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Levisoprenaline is a bioactive chemical. | |||
T20122 |
Isoproterenol sulfate anhydrous
Norisodrine,Novodrine,Novodrin,dl-Isoproterenol sulfate,Isoprenaline sulphate,Aleudrin |
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Isoproterenol sulfate anhydrous is a useful alkaloid. It is used for biological research. | |||
T68259 |
TUPS
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TUPS is a selective soluble epoxide hydrolase inhibitor which protects against isoprenaline-induced cardiac hypertrophy. | |||
T27970 |
Mabuterol free base
Mabuterol,PB 868Cl |
Others | Others |
Mabuterol is a selective agonist of β2 adrenoreceptor with no beta 1-stimulation. Mabuterol inhibited the positive inotropic effect of isoprenaline at 10(-7) g/ml and decreased the maximum driving frequency at 3 X 10(-6) g/ml. Mabuterol was 3 times more p | |||
T69085 |
Mabuterol, (S)-
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Mabuterol, (S)- is a D isoform of Mabuterol, which is a selective β2 adrenoreceptor agonist. Mabuterol has been found to decrease the blood pressure in rats and increase heart rate and contractile force in guinea pigs. Mabuterol inhibited the positive inotropic effect of isoprenaline but has no effect on alpha-adrenergic, acetylcholine and histamine receptors. | |||
T68242 |
D-Mabuterol hydrochloride
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D-Mabuterol hydrochloride is a D isoform of Mabuterol, which is a selective β2 adrenoreceptor agonist. Mabuterol has been found to decrease the blood pressure in rats and increase heart rate and contractile force in guinea pigs. Mabuterol inhibited the positive inotropic effect of isoprenaline but has no effect on alpha-adrenergic, acetylcholine and histamine receptors. | |||
T69084 |
Mabuterol, (R)-
|
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Mabuterol, (R)- is a D isoform of Mabuterol, which is a selective β2 adrenoreceptor agonist. Mabuterol has been found to decrease the blood pressure in rats and increase heart rate and contractile force in guinea pigs. Mabuterol inhibited the positive inotropic effect of isoprenaline but has no effect on alpha-adrenergic, acetylcholine and histamine receptors. | |||
T60713 | TK-129 | ||
TK-129 是具有口服活性的 KDM5B 的有效抑制剂,IC50值为44 nM,并且具有低毒性。TK-129 发挥心脏保护作用,通过抑制 KDM5B 和阻断 KDM5B 相关的 Wnt 通路。TK-129 可用于研究心血管疾病,它能在体内减少异丙肾上腺素诱导的心肌重塑和纤维化,并且在体外减少 Ang II 诱导的心脏成纤维细胞活化。 |