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Search Results for " imipramine "

13

抑制剂 & 化合物

1

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T20025	Imipramine Melipramine,HSDB3100,HSDB 3100,Dimipressin,HSDB-3100
	Imipramine is an agent of tricyclic antidepressants.
T7941	Imipramine hydrochloride 盐酸丙咪嗪,Imipramine (hydrochloride),Tofranil,G 22355,Imipramine HCl,Melipramine	Serotonin Transporter	Neuroscience
	Imipramine hydrochloride (Imipramine HCl) 可抑制血清素转运蛋白，IC50=32 nM。它可阻止胰酶的易位，阻碍 MV 和外泌体的分泌。
T82075	Imipramine pamoate
	Imipramine pamoate为抗抑郁化合物，具有抗抑郁作用。
T74205	Imipramine N-oxide
	Imipramine N-oxide 是 Imipramine 的代谢物。Imipramine 是一种叔胺三环类抗抑郁药。
T9128	N-Desmethyltrimipramine	Others	Others
	N-Desmethyltrimipramine 是一种生化物质。
T21364	Trimipramine Stangyl,Rhotrimine,Surmontil
	Trimipramine is an antidepressant with an anxiety-reducing sedative component to its action.
T74582	Trimipramine N-oxide
	Trimipramine N-oxide 为三环抗抑郁药trimipramine的活性代谢物，其对人去甲肾上腺素单胺转运体(hNAT)、血清素(hSERT)、多巴胺(hDAT)以及人体有机阳离子转运蛋白(hOCT1与hOCT2)的IC50值分别为11.7、3.59、9.4、9.35及27.4 nM。因此，Trimipramine N-oxide在忧郁和焦虑研究中有应用价值。
T0255	Clomipramine hydrochloride Clomipramine HCl,Anafranil,盐酸氯米帕明	Dopamine Receptor; 5-HT Receptor; Serotonin Transporter; Norepinephrine; GST	GPCR/G Protein; Neuroscience; oxidation-reduction
	Clomipramine hydrochloride (Anafranil) 是一种5-羟色胺转运体(Ki:0.14 nM)、去甲肾上腺素转运体(Ki:54 nM)和多巴胺转运体(Ki:3 nM)阻断剂。
T21013	Clomipramine Chlorimipramine,Anafranil,Clomicalm,Anafranil (free base),Clomipramina,氯米帕明	5-HT Receptor	GPCR/G Protein; Neuroscience
	Clomipramine (Clomicalm) 是一种三环类抗抑郁药，能够有效阻断 5-HT 再摄取 (IC50:1.5 nM) ，可用于研究强迫症 (OCD) 及抑郁症。
T24414	Lofepramine hydrochloride WHR-2908A,DB-2182,WHR 2908A
	Lofepramine is a serotonin and norepinephrine reuptake inhibitor. Lofepramine is also a psychotropic IMIPRAMINE derivative.
T25047	Alfetamine alpha-allyl-phenethylamine
	Alfetamine is a chemical compound of the phenethylamine family. It is similar to imipramine and amitriptyline, two tricyclic antidepressants.
T28851	SRA880 free base SRA 880,NVPSRA880,NVP SRA880,NVP-SRA880,SRA-880,SRA880
	SRA880 is a non-peptide antagonist of somatostatin sst1-receptor. SRA880 displayed significantly lower affinity for the other human recombinant somatostatin receptors ( pK(d) < or = 6.0). SRA880 shows a certain binding affinity to the human dopamine D4 re
T26225	SRA880 malonate SRA880,NVPSRA880,NVP-SRA880,NVP-SRA-880,NVP-SRA 880,NVP SRA880
	SRA880 is a non-peptide somatostatin sst(1) receptor antagonist which displays a significantly lower affinity for the other human recombinant somatostatin receptors ( pK(d)= 6.0) or a wide range of neurotransmitter receptors, except for the human dopamine

化合物

Cat.No: T20025

Synonym: Melipramine,HSDB3100,HSDB 3100,Dimipressin,HSDB-3100

Imipramine hydrochloride

Cat.No: T7941

Synonym: 盐酸丙咪嗪,Imipramine (hydrochloride),Tofranil,G 22355,Imipramine HCl,Melipramine

Target: Serotonin Transporter

Imipramine pamoate

Cat.No: T82075

Imipramine N-oxide

Cat.No: T74205

N-Desmethyltrimipramine

Cat.No: T9128

Target: Others

Cat.No: T21364

Synonym: Stangyl,Rhotrimine,Surmontil

Trimipramine N-oxide

Cat.No: T74582

Clomipramine hydrochloride

Cat.No: T0255

Synonym: Clomipramine HCl,Anafranil,盐酸氯米帕明

Target: Dopamine Receptor, 5-HT Receptor, Serotonin Transporter, Norepinephrine, GST

Cat.No: T21013

Synonym: Chlorimipramine,Anafranil,Clomicalm,Anafranil (free base),Clomipramina,氯米帕明

Target: 5-HT Receptor

Lofepramine hydrochloride

Cat.No: T24414

Synonym: WHR-2908A,DB-2182,WHR 2908A

Cat.No: T25047

Synonym: alpha-allyl-phenethylamine

SRA880 free base

Cat.No: T28851

Synonym: SRA 880,NVPSRA880,NVP SRA880,NVP-SRA880,SRA-880,SRA880

SRA880 malonate

Cat.No: T26225

Synonym: SRA880,NVPSRA880,NVP-SRA880,NVP-SRA-880,NVP-SRA 880,NVP SRA880

Cat. No.	Product Name	Target	Signaling Pathways
T1045	Trimipramine maleate Surmontil maleate,马来酸三甲丙咪嗪,三甲丙咪嗪马来酸盐	Dopamine Receptor; 5-HT Receptor; Antibacterial; Adrenergic Receptor; Norepinephrine; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology; Neuroscience
	Trimipramine maleate (Surmontil maleate) 是一种 5-HT 受体拮抗剂，对 5-HT1C、5-HT2和 5-HT1A 受体的 pKi 值分别为 6.39、8.10和 4.66。

天然产物

Trimipramine maleate

Cat.No: T1045

Synonym: Surmontil maleate,马来酸三甲丙咪嗪,三甲丙咪嗪马来酸盐

Target: Dopamine Receptor, 5-HT Receptor, Antibacterial, Adrenergic Receptor, Norepinephrine, Histamine Receptor

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