首页 工具
登录
购物车

搜索结果

Search Results for " gliotoxin "

3

抑制剂 & 化合物

2

天然产物

如果没找到您满意的产品或者您对产品有其他要求,可以联系我们专业顾问为您提供针对性的合理建议。     QQ咨询       网站留言咨询

提交您的定制咨询

点击图片重新获取验证码
Cat. No. Product Name Target Signaling Pathways
T35773 Gliotoxin-13C13

Gliotoxin-13C13

Gliotoxin-13C13is intended for use as an internal standard for the quantification of gliotoxin by GC- or LC-MS. Gliotoxin is an immunosuppressive mycotoxin produced by pathogenic strains ofAspergillusand other fungi with diverse biological activities.1,2,3,4,5,6,7,8It inhibits 20S proteasomal chymotrypsin activity (IC50= 10 μM), blocking the degradation of IκBα and preventing the activation of NF-κB.2,3Gliotoxin induces apoptosis in monocytes and dendritic cells and reduces phagocytosis by neutr...
T70594 Gliotoxin monoacetate

Gliotoxin monoacetate is a toxin found in Aspergillus. It induces apoptosis in cervical cancer cells and chondrosarcoma cells, suppresses the adaptive immune response in leukocytes, and inhibits the proteasome in Plasmodium falciparum.
T70592 Makaluvamine A

Makaluvamine A comes from the fruiting bodies of Didymium bahiense that act as active anti-cancer agents and DNA topo II inhibitors.

化合物

Gliotoxin-13C13
Cat.No: T35773
Synonym: Gliotoxin-13C13
Target:
Gliotoxin monoacetate
Cat.No: T70594
Synonym:
Target:
Makaluvamine A
Cat.No: T70592
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
TN1694 Gliotoxin

Apoptosis; NF-κB; Wnt/beta-catenin; COX; PKA; Antibacterial; Antifection Apoptosis; Cytoskeletal Signaling; Immunology/Inflammation; Microbiology/Virology; Neuroscience; NF-κB; Stem Cells; Tyrosine Kinase/Adaptors
Gliotoxin 是一种次生代谢产物,由A. fumigatus 分泌,可以抑制巨噬细胞的吞噬作用和其他免疫细胞的免疫功能。它通过阻止 IκB 降解来抑制诱导型NF-κB 活性,从而诱导宿主细胞凋亡。它可以激活PKA 并增加细胞内 cAMP 浓度,调节肌动蛋白细胞骨架重排以促进A. fumigatus 内化到肺上皮细胞。
TN3520 Bisdethiobis(methylthio)gliotoxin

PAFR GPCR/G Protein
Bisdethiobis(methylthio)gliotoxin is a platelet activating factor (PAF) antagonist.

天然产物

Gliotoxin
Cat.No: TN1694
Synonym:
Target: Apoptosis, NF-κB, Wnt/beta-catenin, COX, PKA, Antibacterial, Antifection
Bisdethiobis(methylthio)gliotoxin
Cat.No: TN3520
Synonym:
Target: PAFR
TargetMol Loading
联系我们
400-820-0310

上海市静安区江场三路238号8楼