Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T21329 |
Gemcitabine monophosphate disodium salt
Gemcitabine monophosphate disodium salt monohydrate,Gemcitabine monophosphate disodium,GemMP |
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R306465 is a novel HDAC inhibitor with broad-spectrum antitumor activity against solid (IC50: 30 to 300 nM) and hematological malignancies. R306465 was found to be a potent inhibitor of HDAC1 and -8 (class I) in vitro. | |||
T15378 |
Gemcitabine elaidate
Gemcitabine 5'-elaidate,反油酸吉西他滨,吉西他滨反油酸酯,Gemcitabine (elaidate),CO-101,CP-4126 |
Apoptosis; Nucleoside Antimetabolite/Analog; Autophagy | Apoptosis; Autophagy; Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
Gemcitabine elaidate (CP-4126) 是 Gemcitabine 的亲脂性前药。它通过酯酶转化为 Gemcitabine 以被磷酸化。它具有抗肿瘤活性。 | |||
T6069 |
Gemcitabine hydrochloride
Gemcitabine HCl,吉西他滨盐酸盐,Gemzar,LY188011,盐酸吉西他滨,LY 188011 hydrochloride |
Apoptosis; Nucleoside Antimetabolite/Analog; DNA/RNA Synthesis; Autophagy | Apoptosis; Autophagy; Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
Gemcitabine hydrochloride (LY 188011 hydrochloride) 是一种人工合成的胞嘧啶核苷衍生物,一种 DNA 合成抑制剂。Gemcitabine 具有抗肿瘤活性和抗代谢活性。Gemcitabine 可以引起细胞自噬和凋亡。 | |||
T4187 |
Gemcitabine monophosphate sodium salt hydrate
|
Others; DNA; DNA/RNA Synthesis; Autophagy | Autophagy; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Others |
Gemcitabine monophosphate sodium salt hydrate 是Gemcitabine 的单磷酸盐衍生物。 |