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Search Results for " estriol "

10

抑制剂 & 化合物

3

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T37005	Estriol 3-β-D-Glucuronide (sodium salt)
	Estriol 3-β-D-glucuronide is a metabolite of estriol . It is formed from estriol by the UDP-glucuronosyltransferase (UGT) isoform UGT1A10. Estriol 3-β-D-glucuronide binds to basolateral and canalicular liver plasma membranes with Kd values of 85 and 164 μM, respectively. It competitively inhibits the hydrolysis of 4-methylumbelliferyl-β-D-glucuronide and is a substrate for hydrolysis by Klotho-human IgG1 Fc protein (KLFc).
T126484	Estriol 3,17-dihexanoate
	Estriol 3,17-dihexanoate 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T126484。
T124799	Estriol 3-sulfate
	Estriol 3-sulfate 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T124799。
T124856	Estriol 17-sulfate
	Estriol 17-sulfate 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T124856。
T73761	Estriol 16α-(β-D-glucuronide)
	Estriol 16α-(β-D-glucuronide) 是存在于尿中的内源代谢物，可用于研究妊娠。
T20744	Nylestriol Nilestriolum,Lilly 49825,尼尔雌醇,LY 49825,LY-49825,LY49825	Estrogen Receptor/ERR	Endocrinology/Hormones
	Nylestriol (LY 49825) 是雌激素受体的激动剂。
T36913	17-Epiestriol
	17-Epiestriol is a metabolite of estrone .1It is formed from estroneviaa 16α-hydroxy estrone intermediate by reduction of the C-17 ketone. 17-Epiestriol binds to estrogen receptor α (ERα) and ERβ with relative binding affinities of 29 and 80 compared with 17β-estradiol .2 1.Brinton, L.A., Trabert, B., Anderson, G.L., et al.Serum estrogens and estrogen metabolites and endometrial cancer risk among postmenopausal womenCancer Epidemiol. Biomarkers Prev.25(7)1081-1089(2016) 2.Kuiper, G.G.J.M., Lemme...
T33545	Mytatrienediol SC6924,SC 6924,Anvene,SC-6924,Manvene
	Mytatrienediol is a synthetic, steroidal, weak estrogen and estrogen ether derived from estriol.
T36920	16α-hydroxy Dehydroepiandrosterone
	16α-hydroxy Dehydroepiandrosterone is a metabolite of the endogenous steroid hormone dehydroepiandrosterone .116α-hydroxy Dehydroepiandrosterone is formed from dehydroepiandrosteronevia16-hydroxylation by the cytochrome P450 (CYP) isoforms CYP3A4 and CYP3A5 in adult human liver microsomes, as well as by fetal recombinant CYP3A7. It is a precursor to fetal estrogens, including estriol .2 1.Miller, K.K.M., Cai, J., Ripp, S.L., et al.Stereo- and regioselectivity account for the diversity of dehydro...
T36039	16α-Hydroxyestrone
	The naturally-occurring estrogens are estrone , estradiol , and estriol . 16α-hydroxy Estrone (16α-OHE1) is a hydroxylated metabolite of E1 as well as an interconversion product with E2. E1 is 16α-hydroxylated by cytochrome P450 (CYP) isoforms, including CYP1A1, CYP3A5, CYP3A4, and CYP3A7, with CYP3A5 being breast-specific. 16α-OHE1 is sulphatized or glucuronidated before excretion. It is increased in rheumatoid arthritis and decreased by physical activity. Unlike the parent estrogens and other ...

化合物

Estriol 3-β-D-Glucuronide (sodium salt)

Cat.No: T37005

Estriol 3,17-dihexanoate

Cat.No: T126484

Estriol 3-sulfate

Cat.No: T124799

Estriol 17-sulfate

Cat.No: T124856

Estriol 16α-(β-D-glucuronide)

Cat.No: T73761

Cat.No: T20744

Synonym: Nilestriolum,Lilly 49825,尼尔雌醇,LY 49825,LY-49825,LY49825

Target: Estrogen Receptor/ERR

Cat.No: T36913

Cat.No: T33545

Synonym: SC6924,SC 6924,Anvene,SC-6924,Manvene

16α-hydroxy Dehydroepiandrosterone

Cat.No: T36920

16α-Hydroxyestrone

Cat.No: T36039

Cat. No.	Product Name	Target	Signaling Pathways
T1571	Estriol NSC-12169,Oestriol,雌三醇	Estrogen Receptor/ERR; Estrogen/progestogen Receptor; MRP; Endogenous Metabolite	Endocrinology/Hormones; Immunology/Inflammation; Metabolism
	Estriol (Oestriol) 是G 蛋白偶联雌激素受体拮抗剂，能够作用于雌激素受体阴性乳腺癌细胞。
T37499	Estriol 3-glucuronide
	Estriol-3-glucuronide, a natural compound found in urine, is also present in amniotic fluid during normal pregnancy [1][2].
T1683	Actriol 异雌三醇,Epiestriol	Glucocorticoid Receptor	Endocrinology/Hormones
	Actriol (Epiestriol) 是内源性雌激素雌酮的代谢物，拥有抗炎及抗菌活性。

天然产物

Cat.No: T1571

Synonym: NSC-12169,Oestriol,雌三醇

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, MRP, Endogenous Metabolite

Estriol 3-glucuronide

Cat.No: T37499

Cat.No: T1683

Synonym: 异雌三醇,Epiestriol

Target: Glucocorticoid Receptor

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