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Search Results for " exip "

Targets Recommended: Apoptosis RAAS

14

抑制剂 & 化合物

1

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T6595	Moexipril hydrochloride 莫昔普利盐酸盐,Moexipril HCl,RS-10085,SPM 925,CI-925	Apoptosis; RAAS	Apoptosis; Endocrinology/Hormones
	Moexipril hydrochloride (Moexipril HCl) 是一种有口服活性的，不含巯基的血管紧张素转化酶抑制剂，可治疗高血压和充血性心力衰竭。
T3216	Selexipag NS-304,ACT-293987,赛乐西帕,Uptravi	Others; Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation; Others
	Selexipag (ACT-293987) 是前列环素受体激动剂，可引起肺血管舒张，用于治疗肺动脉高压。
T27821	Lexipafant ISV-611,GR-167089,DO-6,BB-882,DO6,BB882
	Lexipafant is a platelet-activating factor (PAF) receptor antagonist.
T71555	Moexipril ethyl ester
	Moexipril ethyl ester is a long-acting, non-sulfhydryl angiotensine-converting enzyme inhibitor.
T69620	Demexiptiline
	Demexiptiline is a tricyclic antidepressant used in France for the treatment of depression. It acts primarily as a norepinephrine reuptake inhibitor similarly to desipramine.
T63377	Moexipril
	Moexipril 是口服具有活力的血管紧张素转换酶 (ACE) 抑制剂。Moexipril 易于透过脂质膜，靶向血浆和组织ACE，改善内皮功能障碍，具有神经保护活性，能够用于研究心血管疾病。
TMIH-0519	Selexipag Active Metabolite-d7
	Selexipag Active Metabolite-d7 是 Selexipag Active Metabolite 的氘代化合物。Selexipag Active Metabolite 的 CAS 号为 475085-57-5。MRE269 是一种口服的长效前列环素受体激动剂前药，是 Selexipag 的活性代谢物，用于治疗肺动脉高压。
T31736	Exiproben DCH 21
	Exiproben is a biochemical.
T67997	mexiprostil
	mexiprostil 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T67997，CAS号为 88980-20-5。
T83766	Moexiprilat RS 10029
	Moexiprilat是一种血管紧张素转换酶(ACE; IC50 = 2.1 nM)的抑制剂，也是前药moexipril的一种活性代谢产物。通过侧链酯水解作用，在体内从moexipril转化而来。Moexiprilat (10 nM)能防止初生大鼠心脏成纤维细胞在雌激素或血管紧张素II刺激下的增殖。在以每天50 mg/kg剂量给药的去卵巢小鼠中，降低平均动脉血压，并增加心房钠尿肽水平，这是高血压的一个标志。
TMIH-0520	Selexipag-d7
	Selexipag-d7 是 Selexipag 的氘代化合物。Selexipag 的 CAS 号为 475086-01-2。Selexipag 是前列环素受体激动剂，可引起肺血管舒张，用于治疗肺动脉高压。
T31737	Exiproben sodium salt DCH 21,DCH-21,DCH21
	Exiproben sodium salt is a biochemical.
T70883	Moexipril-d5
	Moexipril-d5 intended for use as an internal standard for the quantification of moexipril by GC- or LC-MS. Moexipril is a prodrug form of the angiotensin converting enzyme (ACE) inhibitor moexiprilat. It is converted to moexiprilat in vivo by side chain ester hydrolysis. Moexipril inhibits ACE in a cell-free assay (IC50 = 2.7 µM for the rabbit enzyme). It also inhibits phosphodiesterase 4 (IC50s = 38, 160, and 230 µM for PDE4B2, PDE4A5 and PDE4D5, respectively). Moexipril (0.1-30 mg/kg per day) ...
T70884	Moexipril methyl ester
	Moexipril methyl ester is a long-acting, non-sulfhydryl angiotensine-converting enzyme inhibitor.

化合物

Moexipril hydrochloride

Cat.No: T6595

Synonym: 莫昔普利盐酸盐,Moexipril HCl,RS-10085,SPM 925,CI-925

Target: Apoptosis, RAAS

Cat.No: T3216

Synonym: NS-304,ACT-293987,赛乐西帕,Uptravi

Target: Others, Prostaglandin Receptor

Cat.No: T27821

Synonym: ISV-611,GR-167089,DO-6,BB-882,DO6,BB882

Moexipril ethyl ester

Cat.No: T71555

Cat.No: T69620

Cat.No: T63377

Selexipag Active Metabolite-d7

Cat.No: TMIH-0519

Cat.No: T31736

Synonym: DCH 21

Cat.No: T67997

Cat.No: T83766

Synonym: RS 10029

Cat.No: TMIH-0520

Exiproben sodium salt

Cat.No: T31737

Synonym: DCH 21,DCH-21,DCH21

Cat.No: T70883

Moexipril methyl ester

Cat.No: T70884

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-04260	p38 Protein, Human, Recombinant (His) mitogen-activated protein kinase 14,CSPB1,PRKM14,RK,p38α,CSB...	Human	Baculovirus Insect Cells
	MAPK14 contains 1 protein kinase domain and belongs to the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. MAPK14 can be detected in the brain, heart, placenta, pancreas, and skeletal muscle and it is expressed to a lesser extent in the lung, liver, and kidney. MAPK14 is activated by various environmental stresses ...

重组蛋白

p38 Protein, Human, Recombinant (His)

Cat.No: TMPY-04260

Species: Human

Expression System: Baculovirus Insect Cells

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