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Search Results for " elam "

Targets Recommended: Chloride channel P-gp Parasite

20

抑制剂 & 化合物

4

天然产物

7

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T4059	Selamectin UK-124114,司拉克丁,塞拉菌素	Chloride channel; P-gp; Parasite	Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience
	Selamectin (UK-124114) 是半合成的大环内酯，是一种驱虫剂，可增强线虫中谷氨酸和 GABA 门控氯离子通道的开放。它还是抗寄生虫剂，可激活神经元和咽肌中的谷氨酸门控氯离子通道，以预防恶丝虫，淋巴丝虫和线虫感染。它还是 P-糖蛋白底物和抑制剂，IC50为 120 nM。
TP1095	Elamipretide MTP-131,RX-31,SS-31	Others	Others
	Elamipretide (MTP-131) 是一种线粒体靶向抗氧化四肽 (D-Arg-dimethylTyr-Lys-Phe-NH2)，可以减少有毒活性氧的产生并稳定心磷脂，具有血脑屏障渗透性。Elamipretide 是罕见病巴氏综合征的潜在治疗剂。
T34281	Relamorelin BIM28131,RM 131,BIM-28131,BIM-28163,BIM 28163,BIM28163,BIM 28131	GHSR	GPCR/G Protein
	Relamorelin (RM-131)是一种具有选择性和有效性的生长素释放肽/生长激素促分泌素受体 (GHSR) 激动剂，是一种有效的生长素释放肽模拟物，对 GHS-1a 受体具有很高的亲和力。Relamorelin 是一种具有中枢渗透性的五肽，可增加生长激素水平，加速胃排空，具有研究恶病质的潜力。
T6344	Sevelamer hydrochloride Sevelamer HCl	FXR; Autophagy	Autophagy; Metabolism
	Sevelamer hydrochloride (Sevelamer HCl) 是一种磷酸盐结合药物，用于通过与膳食磷酸盐结合并阻止其吸收来治疗高磷血症。
T8644	Elamipretide Triacetate Elamipretide TriTFA	Others	Others
	Elamipretide Triacetate (Elamipretide TriTFA) 是一种芳香族阳离子四肽，可轻松穿透细胞膜并短暂定位于线粒体内膜，在此与心磷脂结合。它已用于研究 Leber 遗传性视神经病变治疗的试验。
T4202	Delamanid 迪拉马尼,德拉马尼,OPC-67683	Anti-infection; Antibacterial; Antibiotic	Microbiology/Virology
	Delamanid (OPC-67683) 是一种新的分枝杆菌细胞壁合成抑制剂，可用于耐多药结核病。
T35371	Colesevelam Hydrochloride	Others	Others
	Colesevelam Hydrochloride 是一种胆汁酸隔离剂，在体外对甘胆酸均具有更高的亲和力。 Colesevelam Hydrochloride 抑制胆汁酸重吸收，导致胆汁酸合成增加并降低胆汁淤积性瘙痒症和克罗恩病患者的胆固醇水平。
T83106	Anselamimab
	Anselamimab (CAEL-101) 为一种靶向血清淀粉样蛋白 A1 (SAA1) 的人源 IgG1-κ 抗淀粉样蛋白原纤维抗体。
TMIH-0180	Delamanid-d4
	Delamanid-d4 是 Delamanid 的氘代化合物。Delamanid 的 CAS 号为 681492-22-8。Delamanid是一种新的分枝杆菌细胞壁合成抑制剂，可用于耐多药结核病。
T10992	Delamanid D4 OPC-67683 D4	Others	Others
	Delamanid D4 is deuterium-labeled Delamanid. Delamanid is a newer mycobacterial cell wall synthesis inhibitor that inhibits the synthesis of mucus acid.
T34948	Trimethylolmelamine
	Trimethylolmelamine is a bioactive chemical.
T6666	Sevelamer Carbonate	Others	Others
	Sevelamer carbonate 是一种口服具有活力的非钙基磷酸盐结合剂，能有效降低体内血清磷水平，但对体内血清钙、氯水平影响极小，可用于研究慢性肾脏病的高磷血症。它被认为是七氟乙烯的一种改进的缓冲形式。
T125790	Delaminomycin A
	Delaminomycin A 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T125790。
TP1096	Elamipretide TFA SS-31 (TFA),MTP-131 (TFA),RX-31 (TFA)	Others	Others
	Elamipretide TFA (RX-31 TFA) 是一种心磷脂过氧化物酶抑制剂和线粒体靶向肽[。
T39236	Relamorelin acetate Relamorelin acetate,RM-131 acetate,BIM-28131acetate
	Relamorelin (RM-131) acetate is a pentapeptide ghrelin analog that acts as a selective agonist for the ghrelin/growth hormone secretagogue receptor (GHSR). It exhibits a high affinity for the GHS-1a receptor, with a Ki value of 0.42 nM. Notably, Relamorelin acetate can cross the blood-brain barrier and target the central nervous system. This compound effectively increases growth hormone levels and promotes faster gastric emptying. Due to these properties, Relamorelin acetate holds promise for it...
TP1095L	Elamipretide acetate MTP 131 acetate,Elamipretide acetate (736992-21-5 Free base)
	Elamipretide acetate (MTP 131 acetate) 是Elamipretide 衍生物。Elamipretide 是一种小的线粒体靶向四肽(D-Arg-dimethylTyr-Lys-Phe-NH2)，可用于研究减少有毒活性氧的产生和稳定心磷脂。
T75262	Relamorelin TFA
	Relamorelin (RM-131) TFA，一种生长素类似物，是一种选择性的生长素释放肽/生长激素促分泌素受体 (GHSR) 激动剂，对GHS-1a 受体的Ki 值为 0.42 nM。Relamorelin TFA 是一种五肽，具有中枢渗透性。Relamorelin TFA 增加生长激素水平，加速胃排空，具有用于恶病质、胃轻瘫和胃/肠运动障碍研究的潜力。
T8831	Elamipretide 2TFA MTP-131 2TFA,RX-31 2TFA,SS-31,MTP-131,SS-31 2TFA,Bendavia	Others	Others
	Elamipretide 2TFA (RX-31 2TFA) 是一种新型的线粒体靶向抗氧化剂。
T22581	Arachidonic Acid Leelamide	Others	Others
	Arachidonic acid leelamide is a phospholipase A2 inhibitor. Phospholipase A is a hydrolase responsible for the release of arachidonic acid from the sn2 position of phospholipids. The released arachidonic acid is then converted to mediators of inflammation
T35884	Sialyl-Lewis X
	Sialyl-Lewis X (sLeX), a sialylated fucosylated tetrasaccharide and endogenous antigen, serves as a high-affinity ligand for selectins (E-, P-, and L-selectin)[1]. It interacts with ELAM-1 and CD62, consequently inhibiting CD62-mediated neutrophil recruitment to inflammation sites[2].

化合物

Cat.No: T4059

Synonym: UK-124114,司拉克丁,塞拉菌素

Target: Chloride channel, P-gp, Parasite

Cat.No: TP1095

Synonym: MTP-131,RX-31,SS-31

Target: Others

Cat.No: T34281

Synonym: BIM28131,RM 131,BIM-28131,BIM-28163,BIM 28163,BIM28163,BIM 28131

Target: GHSR

Sevelamer hydrochloride

Cat.No: T6344

Synonym: Sevelamer HCl

Target: FXR, Autophagy

Elamipretide Triacetate

Cat.No: T8644

Synonym: Elamipretide TriTFA

Target: Others

Cat.No: T4202

Synonym: 迪拉马尼,德拉马尼,OPC-67683

Target: Anti-infection, Antibacterial, Antibiotic

Colesevelam Hydrochloride

Cat.No: T35371

Target: Others

Cat.No: T83106

Cat.No: TMIH-0180

Cat.No: T10992

Synonym: OPC-67683 D4

Target: Others

Trimethylolmelamine

Cat.No: T34948

Sevelamer Carbonate

Cat.No: T6666

Target: Others

Delaminomycin A

Cat.No: T125790

Elamipretide TFA

Cat.No: TP1096

Synonym: SS-31 (TFA),MTP-131 (TFA),RX-31 (TFA)

Target: Others

Relamorelin acetate

Cat.No: T39236

Synonym: Relamorelin acetate,RM-131 acetate,BIM-28131acetate

Elamipretide acetate

Cat.No: TP1095L

Synonym: MTP 131 acetate,Elamipretide acetate (736992-21-5 Free base)

Relamorelin TFA

Cat.No: T75262

Elamipretide 2TFA

Cat.No: T8831

Synonym: MTP-131 2TFA,RX-31 2TFA,SS-31,MTP-131,SS-31 2TFA,Bendavia

Target: Others

Arachidonic Acid Leelamide

Cat.No: T22581

Target: Others

Cat.No: T35884

Cat. No.	Product Name	Target	Signaling Pathways
T5549	Melamine Cyanurotriamide,Cyanuramide,三聚氰胺	Others	Others
	Melamine (Cyanurotriamide) 是合成三聚氰胺树脂和塑料材料的中间体，是环丙嗪的代谢产物。
TN4384	Kelampayoside A	Others	Others
	Kelampayoside A is a natural product from Callicarpa peii.
T11834	Leelamine hydrochloride	Others	Others
	Leelamine hydrochloride, a tricyclic diterpene extracted from pine tree bark, inhibits the transcriptional activity of the androgen receptor, known to regulate fatty acid synthesis [2,3]. This compound acts as a cannabinoid receptor type 1 (CB1) agonist and suppresses SREBP1-regulated fatty acid/lipid synthesis in prostate cancer cells, irrespective of androgen receptor status.
TN3136	5''-O-Syringoylkelampayoside A	Others	Others
	5''-O-Syringoylkelampayoside A 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN3136，CAS号为 1014974-98-1。

天然产物

Cat.No: T5549

Synonym: Cyanurotriamide,Cyanuramide,三聚氰胺

Target: Others

Kelampayoside A

Cat.No: TN4384

Target: Others

Leelamine hydrochloride

Cat.No: T11834

Target: Others

5''-O-Syringoylkelampayoside A

Cat.No: TN3136

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-01167	E-Selectin/CD62E Protein, Human, Recombinant (His) ELAM,selectin E,CD62E,ELAM1,LECAM2,ESEL	Human	HEK293 Cells
	E-Selectin/CD62E Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 60.1 kDa and the accession number is P16581.
TMPK-00487	E-selectin/CD62E Protein, Cynomolgus, Recombinant (aa 22-554, His) selectin E,ELAM,ESEL,SELE,E-Selectin,LECAM2,CD62E,<...	Cynomolgus	HEK293 Cells
	E-Selectin (Endothelial Leukocyte Adhesion Molecule-1, ELAM-1, CD62E), a member of the Selectin family, is a 107 - 115 kDa cell surface glycoprotein. It is transiently expressed on vascular endothelial cells in response to IL-1 beta and TNF-alpha.E-selectin mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with SELPLG/PSGL1. May have a role in capillary morphogenesis. E-selectin/CD62E Protein, Cynomolgus, Recombinant (aa 22-554, His) is expressed...
TMPY-05488	E-Selectin/CD62E Protein, Human, Recombinant (hFc) CD62E,ESEL,ELAM1,ELAM,selectin E,LECAM2	Human	HEK293 Cells
	E-Selectin/CD62E Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 85.4 kDa and the accession number is P16581.
TMPY-03369	E-Selectin/CD62E Protein, Mouse, Recombinant (His) E-selectin,selectin E,CD62E,Elam	Mouse	HEK293 Cells
	E-Selectin/CD62E Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 60 kDa and the accession number is Q3U5F6.
TMPY-03816	E-Selectin/CD62E Protein, Mouse, Recombinant (hFc) Elam,selectin E,E-selectin,CD62E	Mouse	HEK293 Cells
	E-Selectin/CD62E Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 85.5 kDa and the accession number is Q3U5F6.
TMPK-00349	E-Selectin/CD62E Protein, Human, Recombinant (His & Avi) ESEL,RP1-117P20.2,CD62E,ELAM,ELAM1,selecti...	Human	HEK293 Cells
	E-Selectin (Endothelial Leukocyte Adhesion Molecule-1, ELAM-1, CD62E), a member of the Selectin family, is a 107 - 115 kDa cell surface glycoprotein. It is transiently expressed on vascular endothelial cells in response to IL-1 beta and TNF-alpha.E-selectin mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with SELPLG/PSGL1. May have a role in capillary morphogenesis. E-Selectin/CD62E Protein, Human, Recombinant (His & Avi) is expressed in HEK293...
TMPK-00350	E-Selectin/CD62E Protein, Human, Recombinant (His & Avi), Biotinylated CD62E,ELAM,SELE,selectin E,LECAM2,ESEL,RP1-117P20.2...	Human	HEK293 Cells
	E-Selectin (Endothelial Leukocyte Adhesion Molecule-1, ELAM-1, CD62E), a member of the Selectin family, is a 107 - 115 kDa cell surface glycoprotein. It is transiently expressed on vascular endothelial cells in response to IL-1 beta and TNF-alpha.E-selectin mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with SELPLG/PSGL1. May have a role in capillary morphogenesis. E-Selectin/CD62E Protein, Human, Recombinant (His & Avi), Biotinylated is expre...

重组蛋白

E-Selectin/CD62E Protein, Human, Recombinant (His)

Cat.No: TMPY-01167

Species: Human

Expression System: HEK293 Cells

E-selectin/CD62E Protein, Cynomolgus, Recombinant (aa 22-554, His)

Cat.No: TMPK-00487

Species: Cynomolgus

Expression System: HEK293 Cells

E-Selectin/CD62E Protein, Human, Recombinant (hFc)

Cat.No: TMPY-05488

Species: Human

Expression System: HEK293 Cells

E-Selectin/CD62E Protein, Mouse, Recombinant (His)

Cat.No: TMPY-03369

Species: Mouse

Expression System: HEK293 Cells

E-Selectin/CD62E Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-03816

Species: Mouse

Expression System: HEK293 Cells

E-Selectin/CD62E Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00349

Species: Human

Expression System: HEK293 Cells

E-Selectin/CD62E Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00350

Species: Human

Expression System: HEK293 Cells

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