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Search Results for " dronedarone hydrochloride "

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Cat. No.	Product Name	Target	Signaling Pathways
T1073	Dronedarone hydrochloride Dronedarone HCl,SR33589,决奈达隆盐酸盐,盐酸决奈达隆	Potassium Channel; Calcium Channel; Sodium Channel; Adrenergic Receptor; Autophagy	Autophagy; GPCR/G Protein; Membrane transporter/Ion channel; Metabolism; Neuroscience
	Dronedarone hydrochloride (SR33589) 是一种胺碘酮类似物，可抑制 Na+,K+andCa2+的电流，有可能治疗心房颤动。
T35712	Debutyldronedarone hydrochloride SR35021 hydrochloride
	N-Desbutyl dronedarone is an active metabolite of the antiarrhythmic agent dronedarone .1,2,3It is formed from dronedarone by cytochrome P450s (CYPs) and monoamine oxidase (MAO) in human hepatocyte preparations.4N-Desbutyl dronedarone inhibits the binding of 3,3’,5-triiodo-L-thyronine to the thyroid hormone receptors TRα1and TRβ1(IC50s = 59 and 280 μM for the chicken and human receptors, respectively).1It inhibits CYP2J2-mediated formation of 14,15-EET from arachidonic acid and soluble epoxide h...