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抑制剂 & 化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T16914	SP187 UV4,MON-DNJ	Others; Virus Protease; Influenza Virus	Microbiology/Virology; Others
	SP187 (MON-DNJ) 是一种靶向作用于宿主的亚氨基糖。它具有抗丝状病毒感染活性。SP187可用于治疗抗流感和登革热病毒。
T70516	ToP-DNJ
	ToP-DNJ is a selective inhibitor of endoplasmic reticulum α-Glucosidase II, exhibiting antiflaviviral activity.
TQ0155	Miglustat hydrochloride NB-DNJ hydrochloride,盐酸美格鲁特,N-Butyldeoxynojirimycin hydrochloride,OGT918 hydrochloride	Transferase	Metabolism
	Miglustat hydrochloride (N-Butyldeoxynojirimycin hydrochloride) 是一种葡萄糖神经酰胺合酶抑制剂，可用于 I 型戈谢病的相关研究。
TP1080	N-Nonyldeoxynojirimycin NN-DNJ,Nonyl-DNJ
	N-Nonyldeoxynojirimycin (NN-DNJ) is an inhibitor of acid α-glucosidase and α-1,6-glucosidase (IC50s = 0.42 and 8.4 μM, respectively).
T60422	5-C-heptyl-DNJ
	5-C-heptyl-DNJ 是有效的 GAA 激动剂 (Ki = 0.0047 μM)，可增加 GAA 活性。
T70514	Ganciclovir monophosphonate
	Ganciclovir monophosphonate is a synthetic analog of 2'-deoxy-guanosine which is used to treat or prevent cytomegalovirus (CMV) infections. It inhibits the replication of human CMV with an IC50 value of 0.01 μM and is effective against strains of CMV from human, monkey, mouse, and guinea pig.
T70952	UR-MK299
	UR-MK299 is a NPY Y1 receptor antagonist.
T74901	PBI-6DNJ
	PBI-6DNJ 是一种口服有效的多价糖苷酶 (glycosidase) 抑制剂。PBI-6DNJ 对来自小鼠的 α- 葡萄糖苷酶 (α-glucosidase) 具有良好的抑制活性，Ki 为 0.14 μM。PBI-6DNJ 具有良好的降糖活性。PBI-6DNJ 可用于 2 型糖尿病研究。
T70954	SP-187 HCl
	SP-187, also known as N-9-DNJ and UV-4B, is an alpha-Glucosidase inhibitor potentially for the treatment of dengue fever and influenza infection. Proline-producing strains of Serratia marcescens were more osmotolerant than wild-type strains. Growth inhibition by proline analogs was significantly enhanced by increasing the osmotic stress of the medium.

化合物

SP187

Cat.No: T16914

Synonym: UV4,MON-DNJ

Target: Others, Virus Protease, Influenza Virus

Miglustat hydrochloride

Cat.No: TQ0155

Synonym: NB-DNJ hydrochloride,盐酸美格鲁特,N-Butyldeoxynojirimycin hydrochloride,OGT918 hydrochloride

Target: Transferase

N-Nonyldeoxynojirimycin

Cat.No: TP1080

Synonym: NN-DNJ,Nonyl-DNJ

Ganciclovir monophosphonate

Cat. No.	Product Name	Target	Signaling Pathways
T12039	Miglustat N-Butyldeoxynojirimycin,OGT918,美格鲁特,NB-DNJ,N-丙基脱氧野尻霉素	Others	Others
	Miglustat (NB-DNJ) 是一种葡萄糖神经酰胺合成酶抑制剂，可用于I 型戈谢病。
T21344	1-Deoxynojirimycin hydrochloride Moranoline,去氧野艽霉素盐酸盐,AT2220,Duvoglustat hydrochloride,1-Deoxynojirimycin,DNJ,deoxynojirimycin	PI3K; Antibacterial; Antibiotic; Glucosidase	Metabolism; Microbiology/Virology; PI3K/Akt/mTOR signaling
	1-Deoxynojirimycin hydrochloride (Moranoline) 是一种口服有效的 α-葡萄糖苷酶抑制剂，具有降血糖、减肥和抗病毒的作用，可抑制餐后血糖，预防糖尿病。
TQ0298	Fagomine D-Fagomine	ROS; glycosidase	Immunology/Inflammation; Metabolism
	Fagomine (D-Fagomine) 是一种温和的糖苷酶 (glycosidase) 抑制剂，是1-脱氧野尻霉素（DNJ）的类似物，具有降血糖活性，Fagomine 降低了细胞内活性氧（ROS）的产生和丙二醛（MDA）水平。