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Cat. No.	Product Name	Target	Signaling Pathways
T0182	Clopidogrel (S)-Clopidogrel,SR-25990C,氯吡格雷	P2Y Receptor	GPCR/G Protein; Neuroscience
	Clopidogrel (SR-25990C) 是一种 P2Y12 受体拮抗剂，可降低血小板聚集，用于抑制冠状动脉疾病、周围血管疾病和脑血管疾病中的血凝块。
T0182L	Clopidogrel hydrogen sulfate 硫酸氢氯吡格雷,(S)-(+)-Clopidogrel hydrogen sulfate,(S)-(+)-Clopidogrel bisulfate,SR-25990C,Clopidogrel,硫酸氯吡格雷	P450; P2Y Receptor	GPCR/G Protein; Metabolism; Neuroscience
	Clopidogrel hydrogen sulfate ((S)-(+)-Clopidogrel bisulfate) 是一种抗血小板药物，可防止血栓形成。它抑制 CYP2B6和 CYP2C19，IC50分别为 18.2 和 524 nM。它是一种选择性的高亲和力 P2Y12 受体拮抗剂，可抑制纤维蛋白原与血小板的结合以及血小板的粘附和聚集。
T0182L2	(±) Clopidogrel hydrogen sulfate 硫酸氢氯吡格雷,Plavix,Clopidogrel hydrogen sulfate,Iscover	P2Y Receptor	GPCR/G Protein; Neuroscience
	(±) Clopidogrel hydrogen sulfate (Iscover) 是一种在药理学和结构上类似于ticlopidine 的抗血小板药物，用于抑制脑血管疾病、外周血管疾病和冠状动脉疾病等各种疾病中的血栓。
T38506	cis-Clopidogrel-MP derivative cis-Clopidogrel-MP derivative,Clopidogrel-MP-AM
	cis-Clopidogrel-MP derivative, also known as Clopidogrel-MP-AM, is a 3’-methoxyacetophenone derivative of Clopidogrel active metabolite. This compound is an orally-active platelet inhibitor specifically targeting the P2Y12 receptor.
T35431	(±)-Clopidogrel (hydrochloride)
	Clopidogrel is an antithrombic compound whose active metabolite is a selective, irreversible antagonist of the platelet purinergic P2Y12 receptor (IC50 = 100 nM). Clopidogrel inhibits ADP-induced platelet aggregation ex vivo and functions as a prodrug whereupon biotransformation to its active metabolite via CYP2C19 in the liver enables its anti-aggregating activity. Marketed under the name Plavix , clopidogrel in combination with aspirin has been shown to be beneficial in the prevention of vascu...
T36222	2-oxo Clopidogrel
	2-oxo Clopidogrel is an intermediary metabolite of clopidogrel . Clopidogrel is a prodrug that is converted to its active metabolite via two sequential oxidative steps. The first step leads to formation of 2-oxo clopidogrel, followed by conversion to the active metabolite, which binds specifically and irreversibly to the platelet P2Y12 purinergic receptor, inhibiting ADP-mediated platelet activation and aggregation.
T5501	Clopidogrel thiolactone 2-oxoclopidogrel	P2Y Receptor	GPCR/G Protein; Neuroscience
	Clopidogrel thiolactone (2-oxoclopidogrel) 是一种有效的 P2Y12 受体抑制剂, 是一种有效的抗血小板聚集化合物。Clopidogrel thiolactone是Clopidogrel第一次氧化活化产生的活性代谢中间体。
T71254	Clopidogrel HCl
	Clopidogrel HCl is the salt form of Clopidogrel (free base), an inhibitor of ADP-induced platelet aggregation acting by direct inhibition of adenosine diphosphate (ADP) binding to its receptor and of the subsequent ADP-mediated activation of the glycoprotein GPIIb/IIIa complex.
T36112	Clopidogrel Carboxylic Acid (hydrochloride)
	Clopidogrel is an antithrombic compound whose active metabolite is a selective, irreversible antagonist of the platelet purinergic P2Y12 receptor (IC50 = 100 nM). Clopidogrel inhibits ADP-induced platelet aggregation ex vivo and functions as a prodrug whereupon biotransformation to its active thiol metabolite via CYP2C19 in the liver enables its anti-aggregating activity. An estimated 15% of administered clopidogrel is metabolized by CYP2C19 to the thiol metabolite. Clopidogrel carboxylic acid i...
T125853	Clopidogrel Related Compound A
	Clopidogrel Related Compound A 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T125853，CAS号为 144457-28-3。
T125846	Clopidogrel Related Compound B
	Clopidogrel Related Compound B 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T125846，CAS号为 144750-52-7。
T126236	Clopidogrel Related Compound C
	Clopidogrel Related Compound C 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T126236，CAS号为 120202-71-3。
T0179	Ticagrelor 替格瑞洛,替卡格雷,AR-C 126532XX,AZD6140	P450; P2Y Receptor	GPCR/G Protein; Metabolism; Neuroscience
	Ticagrelor (AR-C 126532XX) (AZD6140) 是可逆的，可口服的 P2Y12受体拮抗剂，可抑制血小板聚集。
T21059	Ticagrelor metabolite M5 Ticagrelor metabolite M5,,T437700,替格瑞洛杂质H,AR-C133913XX	P2Y Receptor	GPCR/G Protein; Neuroscience
	Ticagrelor metabolite M5 (T437700) 是 Ticagrelor 的代谢物，是 P2Y12 受体的第一个可逆口服拮抗剂。与氯吡格雷相比，替格瑞洛对 ADP 受体具有更快和更一致的抑制作用。替格瑞洛用于治疗急性冠状动脉综合征(ACS)。
T71363	ACT-281959
	ACT-281959, a prodrug of ACT-246475, is a novel potent and selective P2Y12 Receptor Antagonist with a Wider Therapeutic Window in the Rat Than Clopidogrel. ACT-281959 showed antithrombotic efficacy after oral administration in the rat ferric chloride model. ACT-281959 entered clinical studies in healthy volunteers.
T20765	Atorvastatin 阿托伐他汀,阿伐他汀	HMG-CoA Reductase; Autophagy	Autophagy; Metabolism
	Atorvastatin 是一种具有口服活性的 HMG-CoA 还原酶抑制剂，通过激活肝细胞色素p450加快代谢，具有有效降低血脂的能力。Atorvastatin 以 IC50 值分别为 0.39 μM 和 2.39 μM 来抑制人 SV-SMC 细胞的增殖和侵袭。Atorvastatin 与氯吡格雷同时服用两种可能会导致患者血栓事件增加。
T75242	Bivalirudin TFA
	Bivalirudin TFA 是20个氨基多肽，可逆地抑制凝血酶。

化合物

Cat.No: T0182

Synonym: (S)-Clopidogrel,SR-25990C,氯吡格雷

Target: P2Y Receptor

Clopidogrel hydrogen sulfate

Cat.No: T0182L

Synonym: 硫酸氢氯吡格雷,(S)-(+)-Clopidogrel hydrogen sulfate,(S)-(+)-Clopidogrel bisulfate,SR-25990C,Clopidogrel,硫酸氯吡格雷

Target: P450, P2Y Receptor

(±) Clopidogrel hydrogen sulfate

Cat.No: T0182L2

Synonym: 硫酸氢氯吡格雷,Plavix,Clopidogrel hydrogen sulfate,Iscover

Target: P2Y Receptor

cis-Clopidogrel-MP derivative

Cat.No: T38506

Synonym: cis-Clopidogrel-MP derivative,Clopidogrel-MP-AM

(±)-Clopidogrel (hydrochloride)

Cat.No: T35431

2-oxo Clopidogrel

Cat.No: T36222

Clopidogrel thiolactone

Cat.No: T5501

Synonym: 2-oxoclopidogrel

Target: P2Y Receptor

Clopidogrel HCl

Cat.No: T71254

Clopidogrel Carboxylic Acid (hydrochloride)

Cat.No: T36112

Clopidogrel Related Compound A

Cat.No: T125853

Clopidogrel Related Compound B

Cat.No: T125846

Clopidogrel Related Compound C

Cat.No: T126236

Cat.No: T0179

Synonym: 替格瑞洛,替卡格雷,AR-C 126532XX,AZD6140

Target: P450, P2Y Receptor

Ticagrelor metabolite M5

Cat.No: T21059

Synonym: Ticagrelor metabolite M5,,T437700,替格瑞洛杂质H,AR-C133913XX

Target: P2Y Receptor

Cat.No: T71363

Cat.No: T20765

Synonym: 阿托伐他汀,阿伐他汀

Target: HMG-CoA Reductase, Autophagy

Bivalirudin TFA

Cat.No: T75242

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