Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T1698 |
Carvedilol EP IMpurity E
Carvedilol USP E,Carvedilol Impurity E,卡维地洛杂质 |
Others | Others |
Carvedilol EP IMpurity E (Carvedilol USP E) 用作药物中间体。 | |||
T0342 |
Carvedilol phosphate hemihydrate
Carvedilol phosphate,BM 14190 (phosphate hemihydrate),卡维地洛磷酸盐 |
VEGFR; Others; Potassium Channel; LDL; Integrin; Gap Junction Protein; NADPH; Adrenergic Receptor; Autophagy | Angiogenesis; Autophagy; Cytoskeletal Signaling; GPCR/G Protein; Membrane transporter/Ion channel; Metabolism; Neuroscience; Others; Tyrosine Kinase/Adaptors |
Carvedilol phosphate hemihydrate (BM 14190 phosphate hemihydrate) 是一种外消旋混合物,是一种非选择性β/α-1受体阻断剂,具有抗高血压活性且缺乏内在拟交感神经活性。 | |||
T10686 |
Carvedilol metabolite 4-Hydroxyphenyl Carvedilol
4-Hydroxyphenyl Carvedilol,4-Hydroxycarvedilol |
Others | Others |
4-Hydroxyphenyl Carvedilol is a metabolite of Carvedilol. Carvedilol is a beta-blocker/alpha-1 blocker. | |||
T19136 |
4-Hydroxyphenyl Carvedilol-d5
4-Hydroxycarvedilol D5,4-Hydroxyphenyl Carvedilol D5 |
Others | Others |
4-Hydroxyphenyl Carvedilol D5 is the deuterium labeled 4-Hydroxyphenyl Carvedilol. | |||
T35845 |
(R,S)-Carvedilol Glucuronide
|
||
(R,S)-Carvedilol glucuronide is a racemic mixture of the carvedilol metabolites (R)-carvedilol glucuronide and (S)-carvedilol glucuronide. (R)-Carvedilol glucuronide is formed via glucuronidation of (R)-carvedilol by the UDP-glucuronosyltransferase (UGT) isoforms UGT1A1 and UGT2B4. (S)-Carvedilol glucuronide is formed via glucuronidation of (S)-carvedilol by UGT2B4 and UGT2B7. | |||
T12615 |
(R)-Carvedilol
(R)-BM 14190,(R)-卡维地洛 |
Others | Others |
(R)-Carvedilol is a non-selective blocker of β/α-1. (R)-Carvedilol exerts protection against the vascular or cardiac toxicity of Doxorubicin (DOX). | |||
T12794 |
(S)-Carvedilol
(S)-BM 14190,(S)-卡维地洛 |
Others | Others |
(S)-Carvedilol is a non-selective β/α-1 blocker.It exerts protection against the vascular or cardiac toxicity of Doxorubicin (DOX). | |||
T8863 |
VK-II-36
|
Others | Others |
VK-II-36 是 carvedilol 的类似物,能够在不阻断 β 受体的情况下抑制肌浆网钙释放。它能够抑制早期和延迟后去极化诱发的触发活动,可用于局灶性室性心律失常的研究。 | |||
T8891 |
Homo-VK-II-36
Homo-V-II-36 |
Others | Others |
Homo-VK-II-36 (Homo-V-II-36) 是一种卡维地洛类似物,其作用是通过 RyR2 通道抑制储存超载诱导的钙释放。 | |||
T8965 |
VK-II-86
|
Others | Others |
VK-II-86 是一种非β-阻断卡维地洛类似物。它可以防止哇巴因诱导的心脏毒性。 | |||
T28675 |
SB 211475
SB-211475,SB211475 |
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SB 211475, a metabolite of carvedilol, is a novel antihypertensive agent and a potent antioxidant. |