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Targets Recommended: MAO Imidazoline Receptor

6

抑制剂 & 化合物

1

化合物库

14

重组蛋白

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Cat. No. Product Name
L7600 趋化因子抑制剂库

59 compounds
59 种趋化因子或其受体抑制剂的独特集合,可用于高通量筛选和高内涵筛选;

化合物库

趋化因子抑制剂库
Cat.No: L7600
Compounds: 59
Cat. No. Product Name Target Signaling Pathways
T15010 CR4056

6-(1H-imidazol-1-yl)-2-phenylquinazoline

MAO; Imidazoline Receptor Metabolism; Neuroscience
CR4056 (6-(1H-imidazol-1-yl)-2-phenylquinazoline) 是一种特异性 MAO-A 抑制剂,IC50 为 202.7 nM,是 I2-咪唑啉受体的配体,IC50 为 596 nM。
T12617L (R)​-​CR8

(R)-CR8,(R)-Isomer,(2R)-2-[[9-异丙基-6-[[[4-(2-吡啶基)苯基]甲基]氨基]-9H-嘌呤-2-基]氨基]-1-丁醇,CR8

Apoptosis; CDK Apoptosis; Cell Cycle/Checkpoint
(R)​-​CR8 ((R)-Isomer) 是 Roscovitine 类似物,是CDK1/2/5/7/9抑制剂。它作为一种分子胶降解剂来消耗细胞周期蛋白 K。它诱导细胞凋亡并具有神经保护作用。
TD0062 6-CR110 [6-Carboxyrhodamine 110] *Single isomer*

6-羧基罗丹明110(单一化合物)

6-CR110 [6-Carboxyrhodamine 110] *Single isomer* is a Fluorescein for peptide and oligonucleotide labeling. Compared to fluorescein labeling reagents such as FITC and FAM, CR110 reagents give more photostable and pH-independent bioconjugates that have the absorption maximum around the preferred 488 nm excitation wavelength. They are photostable alternative reagents superior to FITC and FAM.
TD0060 5(6)-CR110 [5-(and 6)-Carboxyrhodamine 110] *Mixed isomers*

5(6)-羧基罗丹明110(混合物)

5(6)-CR110 [5-(and 6)-Carboxyrhodamine 110] *Mixed isomers* is a Fluorescein for peptide and oligonucleotide labeling. Compared to fluorescein labeling reagents such as FITC and FAM, CR110 reagents give more photostable and pH-independent bioconjugates that have the absorption maximum around the preferred 488 nm excitation wavelength. They are photostable alternative reagents superior to FITC and FAM.
TD0063 5(6)-CR110, SE [5-(and 6)-Carboxyrhodamine 110, succinimidyl ester] *Mixed isomers*

5(6)-羧基罗丹明110琥珀酰亚胺酯(混合物)

5(6)-CR110, SE [5-(and 6)-Carboxyrhodamine 110, succinimidyl ester] *Mixed isomers* is a Fluorescein for peptide and oligonucleotide labeling. Compared to fluorescein labeling reagents such as FITC and FAM, CR110 reagents give more photostable and pH-independent bioconjugates that have the absorption maximum around the preferred 488 nm excitation wavelength. They are photostable alternative reagents superior to FITC and FAM.
TD0065 6-CR110, SE [6-Carboxyrhodamine 110, succinimidyl ester]*Single isomer*

6-羧基罗丹明110琥珀酰亚胺酯(单一化合物)

6-CR110, SE [6-Carboxyrhodamine 110, succinimidyl ester]*Single isomer* is a Fluorescein for peptide and oligonucleotide labeling. Compared to fluorescein labeling reagents such as FITC and FAM, CR110 reagents give more photostable and pH-independent bioconjugates that have the absorption maximum around the preferred 488 nm excitation wavelength. They are photostable alternative reagents superior to FITC and FAM.

化合物

CR4056
Cat.No: T15010
Synonym: 6-(1H-imidazol-1-yl)-2-phenylquinazoline
Target: MAO, Imidazoline Receptor
(R)​-​CR8
Cat.No: T12617L
Synonym: (R)-CR8,(R)-Isomer,(2R)-2-[[9-异丙基-6-[[[4-(2-吡啶基)苯基]甲基]氨基]-9H-嘌呤-2-基]氨基]-1-丁醇,CR8
Target: Apoptosis, CDK
6-CR110 [6-Carboxyrhodamine 110] *Single isomer*
Cat.No: TD0062
Synonym: 6-羧基罗丹明110(单一化合物)
Target:
5(6)-CR110 [5-(and 6)-Carboxyrhodamine 110] *Mixed isomers*
Cat.No: TD0060
Synonym: 5(6)-羧基罗丹明110(混合物)
Target:
5(6)-CR110, SE [5-(and 6)-Carboxyrhodamine 110, succinimidyl ester] *Mixed isomers*
Cat.No: TD0063
Synonym: 5(6)-羧基罗丹明110琥珀酰亚胺酯(混合物)
Target:
6-CR110, SE [6-Carboxyrhodamine 110, succinimidyl ester]*Single isomer*
Cat.No: TD0065
Synonym: 6-羧基罗丹明110琥珀酰亚胺酯(单一化合物)
Target:
Cat. No. Product Name Species Expression System
TMPY-03655 GADD45G Protein, Human, Recombinant

GADD45γ,growth arrest and DNA-damage-inducible, γ,DDIT2,grow...

Human E. coli
GADD45G, also known as CR6, is part of the nuclear proteins to interact with various proteins whose transcript levels are raised after stressful growth arrest conditions and treatment with DNA-damaging agents. GADD45G reacts to environmental stresses by mediating activation of the p38/JNK pathway which is mediated through their protein binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. GADD45G acts as a new-age tumor suppressor however is being fr...
TMPJ-00711 GADD45G Protein, Human, Recombinant (His)

Cytokine-Responsive Protein CR6,Growth Arr...

Human E. coli
Growth Arrest and DNA Damage-Inducible Protein GADD45 Υ (GADD45G) is a nuclear protein which belongs to the GADD45 family. GADD45G is highly expressed in placenta. GADD45G interacts with various proteins whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. GADD45G responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. GADD45G is also involved in the regulation of growth and apo...
TMPJ-00567 NCR1 Protein, Human, Recombinant (hFc)

hNKp46,Natural cytotoxicity triggering receptor 1,N...

Human HEK293 Cells
Natural cytotoxicity triggering receptor 1(NCR1) is a single-pass type I membrane protein .It contains 2 Ig-like (immunoglobulin-like) domains and belongs to the natural cytotoxicity receptor (NCR) family. The protein is a natural killer (NK) lymphocyte-activating receptor. It is involved in major aspects of NK immune function and shows a high degree of lineage specificity in blood and bone marrow.
TMPK-00614 NKp46/NCR1 Protein, Human, Recombinant (His)

NKp46,MAR-1,Ly94,NCR1,NKP46FLJ990...

Human HEK293 Cells
NKp46, along with NKp30 and NKp44, are activating receptors that have been collectively termed the natural cytotoxicity receptors (NCR).These receptors lack significant sequence homology to one another. They are expressed almost exclusively by NK cells and play a major role in triggering some of the key lytic activities of NK cells. NKp46/NCR1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 27.5 kDa and the accession numb...
TMPY-03010 NRG1 beta 1 Protein, Human, Recombinant

NDF,GGF,MSTP131,Neuregulin 1,MST131,ARIA,NRG1-IT2,SMDF,NRG1 ...

Human HEK293 Cells
NRG1 beta 1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 26.8 kDa and the accession number is Q02297-6.
TMPK-00615 NKp46/NCR1 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated

CD335,NCR1,NKp46,NKP46FLJ99094,Ly...

Human HEK293 Cells
NKp46, along with NKp30 and NKp44, are activating receptors that have been collectively termed the natural cytotoxicity receptors (NCR).These receptors lack significant sequence homology to one another. They are expressed almost exclusively by NK cells and play a major role in triggering some of the key lytic activities of NK cells. NKp46/NCR1 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular we...
TMPJ-00827 Tau-D Protein, Human, Recombinant (His)

PHF-Tau,MAPTL,MAPT,Paired Helical Filament-Tau,Micr...

Human E. coli
Microtubule-Associated Protein TAU is abundantly expressed in neurons of the central nervous system and less commonly expressed elsewhere, but is also expressed at very low levels in CNS astrocytes and oligodendrocytes. Tau interacts with tubulin to stabilize microtubules and promotes tubulin assembly into microtubules. The C-terminus of TAU binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau acts as a linker protein. When tau is defective,...
TMPY-03128 LAIR1 Protein, Mouse, Recombinant (hFc)

leukocyte-associated immunoglobulin-like receptor 1,BB1152

Mouse HEK293 Cells
LAIR1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39.6 kDa and the accession number is Q8BG84-6.
TMPY-04277 CD45 Protein, Mouse, Recombinant (hFc)

Cd45,protein tyrosine phosphatase, receptor type, C,Ly-5,L-C...

Mouse HEK293 Cells
CD45 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 71.7 kDa and the accession number is P06800-6.
TMPY-05798 VEGF145 Protein, Human, Recombinant

血管内皮生长因子,vascular endothelial growth factor A,VPF,MVCD1,VEGF...

Human HEK293 Cells
VEGF145 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 16.92 kDa and the accession number is P15692-6.
TMPY-02600 NRG1 beta 1 Protein, Human, Recombinant (EGF Domain, hFc)

neuregulin 1,HRGA,NRG1 β1,HGL,MST131,MSTP131,HRG,ARIA,NDF,GG...

Human HEK293 Cells
NRG1 beta 1 Protein, Human, Recombinant (EGF Domain, hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 36.7 kDa and the accession number is Q02297-6.
TMPY-02705 NRG1 beta 1 Protein, Human, Recombinant (hFc)

MSTP131,HRG1,NRG1-IT2,ARIA,HGL,SMDF,GGF,HRG,NDF,MST131,neure...

Human HEK293 Cells
NRG1 beta 1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 55.2 kDa and the accession number is Q02297-6.
TMPK-01358 SIRP alpha V6 Protein, Human, Recombinant (His & Avi)

P84,SIRPA,SIRP alpha,SHPS-1,MFR,BIT,MYD1,SIRP α V6,...

Human HEK293 Cells
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V6 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-Hi...
TMPK-01364 SIRP alpha V6 Protein, Human, Recombinant (His & Avi), Biotinylated

SIRP α,MFR,SHPS1,SIRPA,BIT,SHPS-1,MYD-1,SIRP alpha,P84,CD172...

Human HEK293 Cells
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V6 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian c...

重组蛋白

GADD45G Protein, Human, Recombinant
Cat.No: TMPY-03655
Species: Human
Expression System: E. coli
GADD45G Protein, Human, Recombinant (His)
Cat.No: TMPJ-00711
Species: Human
Expression System: E. coli
NCR1 Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-00567
Species: Human
Expression System: HEK293 Cells
NKp46/NCR1 Protein, Human, Recombinant (His)
Cat.No: TMPK-00614
Species: Human
Expression System: HEK293 Cells
NRG1 beta 1 Protein, Human, Recombinant
Cat.No: TMPY-03010
Species: Human
Expression System: HEK293 Cells
NKp46/NCR1 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
Cat.No: TMPK-00615
Species: Human
Expression System: HEK293 Cells
Tau-D Protein, Human, Recombinant (His)
Cat.No: TMPJ-00827
Species: Human
Expression System: E. coli
LAIR1 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-03128
Species: Mouse
Expression System: HEK293 Cells
CD45 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-04277
Species: Mouse
Expression System: HEK293 Cells
VEGF145 Protein, Human, Recombinant
Cat.No: TMPY-05798
Species: Human
Expression System: HEK293 Cells
NRG1 beta 1 Protein, Human, Recombinant (EGF Domain, hFc)
Cat.No: TMPY-02600
Species: Human
Expression System: HEK293 Cells
NRG1 beta 1 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-02705
Species: Human
Expression System: HEK293 Cells
SIRP alpha V6 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-01358
Species: Human
Expression System: HEK293 Cells
SIRP alpha V6 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-01364
Species: Human
Expression System: HEK293 Cells
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