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Cat. No. Product Name Target Signaling Pathways
TP1187 C-Type Natriuretic Peptide (CNP) (1-22), human

CNP (1-22), human

RAAS Endocrinology/Hormones
C-Type Natriuretic Peptide (CNP) (1-22), human 是一种利钠肽受体 B (NPR-B) 激动剂,是一种 CNP 的 1-22 片段。它对生理激动剂组胺和 5-HT 刺激或直接由 Forskolin 刺激的 cAMP 合成具有抑制作用。其中CNP 是一种有效的、内皮衍生的松弛剂和生长抑制因子。
T19244 CNP-AFU

2-Chloro-4-nitrophenyl α-L-fucopyranoside

Others Others
CNP-AFU (2-Chloro-4-nitrophenyl α-L-fucopyranoside) 是 α-L-岩藻糖苷酶的底物。
T39392L C-Type Natriuretic Peptide (CNP) (1-22), human acetate

C-Type Natriuretic Peptide (CNP) (1-22), human acetate(1966153-17-2 Free base)

Others Others
C-Type Natriuretic Peptide (CNP) (1-22), human acetate 是一种利钠肽受体 B (NPR-B) 的激动剂,一种内皮衍生的松弛剂和生长抑制因子。 C-Type Natriuretic Peptide (CNP) (1-22), human acetate 抑制由组胺和 5-HT 或直接由毛喉素刺激的 cAMP 合成。
T27606 Indantadol HCl

CHF-3381,CMP-3381,GT-3381,V-3381,CNP-3381,Indantadol

MAO; NMDAR Metabolism; Neuroscience
Indantadol HCl (CHF-3381) 是一种 NMDA 拮抗剂和非选择性 MAO 抑制剂。
T37834 G3-CNP

G3-CNP is a colorimetric substrate for α-amylases.1Upon hydrolysis by α-amylases, 2-chloro-4-nitrophenol is released which can be quantified by colorimetric detection at 405 nm as a measure of enzyme activity. G3-CNP has been used to characterize the activity of human pancreatic or salivary amylase.
T13253 Umibecestat

CNP520

BACE Neuroscience
Umibecestat 是一种β-位点淀粉样前体蛋白裂解酶-1 (BACE-1) 抑制剂,对人 BACE-1 和小鼠 BACE-1 的 IC50 分别为 11 nM 和 10 nM,可用于阿尔茨海默病的研究。
T39392 C-Type Natriuretic Peptide (CNP) (1-22), human TFA

C-Type Natriuretic Peptide (CNP) (1-22), human (TFA), is a 22 amino acid fragment of CNP and functions as an agonist for the natriuretic peptide receptor B (NPR-B). It can inhibit cAMP synthesis, which is induced by histamine, 5-HT, or Forskolin. Additionally, CNP exhibits strong endothelial-derived relaxation properties and acts as a growth inhibitor.
T80156 CNP-38

CNP-38是C型钠尿肽,具有调节血压和体液平衡的生物活性。
T24924 Umibecestat HCl (1387560-01-1 free base)

CNP 520,Umibecestat HCl,Umibecestat hydrochloride,CNP520,CNP-520

Umibecestat is a beta-secretase inhibitor. CNP520 has a selectivity, pharmacodynamics, and distribution profile suitable for AD prevention studies.
T69663 G108

G108 is a Novel h-cGAS specific inhibitor for repression of dsDNA-triggered interferon expression (IC50 of 27.5 nM and 5150 nM for h-cGAS and m-cGAS, respectively).
T37835 2-Chloro-4-nitrophenyl-α-D-glucopyranoside

Carbohydrates conjugated with 2-chloro-4-nitrophenyl (CNP) serve as chromogenic substrates in assays for enzymes that release CNP from the conjugated carbohydrate. For example, CNP-β-D-maltoheptaoside and CNP-α-maltotrioside are chromogenic substrates for α-amylase. 2-Chloro-4-nitrophenyl-α-D-glucopyranoside is a conjugate of CNP and α-D-glucose. The related conjugate between CNP and β-D-glucose, 2-chloro-4-nitrophenyl β-D-glucopyranoside, is used as a chromogenic substrate for glycosyltransfera...
TP1581 C-Type Natriuretic Peptide (1-53), human

CNP, a member of the natriuretic peptide family, was first identified in porcine brain and later found in other mammals as well as non-mammals. Processing of the CNP precursor gives rise to CNP-22 and its N-terminally elongated form, CNP-53. The CNPs shar
T78007 Vasonatrin Peptide (VNP) TFA

Vasonatrin Peptide (VNP) TFA 是一种由心钠素 (ANP) 和C型利钠肽 (CNP) 嵌合而成的肽类化合物。它整合了CNP的静脉扩张功能、ANP的利尿效果,并展现出与ANP或CNP无关的特有动脉扩张特性。Vasonatrin Peptide TFA 透过cGMP-PKG信号途径发挥其对内质网应激介导的糖尿病心脏缺血再灌注损害的保护作用。
TP1872 Vasonatrin Peptide (VNP)

Vasonatrin Peptide VNP

Vasonatrin peptide (VNP) is a chimera of atrial natriuretic peptide (ANP) and C-type natriuretic peptide (CNP) with potent venodilating and natriuretic activity.
T82961 ASB20123

ASB20123 是一款融合了CNP/ghrelin序列的嵌合肽,具有促进骨骼生长的效能,适用于研究生长障碍和侏儒症。
T61496 NPR-C activator 1

NPR-C activator 1 (Compound 1) is a potent activator of natriuretic peptide receptor C (NPR-C), a receptor involved in the regulation of vascular homeostasis. It acts as a potent agonist (EC50 ~ 1 μM) of C-type natriuretic peptide (CNP), showing promising in vivo pharmacokinetic properties [1].
T76277 Vosoritide

Vosoritide (BMN 111) 为改良重组CNP (C型钠尿肽) 类似物,作用于NPR-B (B型钠尿肽受体),能有效降低FGFR3 (成纤维细胞生长因子受体 3) 活性,主要应用于软骨症和侏儒症研究领域。
T69664 Umibecestat HCl

Umibecestat, also known as CNP-520, is a beta-secretase inhibitor and is a drug candidate for prevention trials in Alzheimer's disease. CNP520 has a selectivity, pharmacodynamics, and distribution profile suitable for AD prevention studies. CNP520 reduced brain and cerebrospinal fluid (CSF) Aβ in rats and dogs, and Aβ plaque deposition in APP-transgenic mice. CNP520 reduces Aβ load and neuroinflammation in APP‐transgenic mice
T76334 Cenderitide

Cenderitide 是一种有效的颗粒鸟酰基环化酶受体 (pGC) 激动剂。Cenderitide 是一种由 C 型利钠肽 (CNP) 与石斛利钠肽 (DNP) 的 C 端融合而成的利钠肽 (NP) 。Cenderitide 可激活 pGC-A 和 pGC-B,激活第二信使 cGMP,抑制醛固酮 (aldosterone),在不降低血压的情况下保持 GFR 。Cenderitide 可用于心力衰竭的研究。

化合物

C-Type Natriuretic Peptide (CNP) (1-22), human
Cat.No: TP1187
Synonym: CNP (1-22), human
Target: RAAS
CNP-AFU
Cat.No: T19244
Synonym: 2-Chloro-4-nitrophenyl α-L-fucopyranoside
Target: Others
C-Type Natriuretic Peptide (CNP) (1-22), human acetate
Cat.No: T39392L
Synonym: C-Type Natriuretic Peptide (CNP) (1-22), human acetate(1966153-17-2 Free base)
Target: Others
Indantadol HCl
Cat.No: T27606
Synonym: CHF-3381,CMP-3381,GT-3381,V-3381,CNP-3381,Indantadol
Target: MAO, NMDAR
G3-CNP
Cat.No: T37834
Synonym:
Target:
Umibecestat
Cat.No: T13253
Synonym: CNP520
Target: BACE
C-Type Natriuretic Peptide (CNP) (1-22), human TFA
Cat.No: T39392
Synonym:
Target:
CNP-38
Cat.No: T80156
Synonym:
Target:
Umibecestat HCl (1387560-01-1 free base)
Cat.No: T24924
Synonym: CNP 520,Umibecestat HCl,Umibecestat hydrochloride,CNP520,CNP-520
Target:
G108
Cat.No: T69663
Synonym:
Target:
2-Chloro-4-nitrophenyl-α-D-glucopyranoside
Cat.No: T37835
Synonym:
Target:
C-Type Natriuretic Peptide (1-53), human
Cat.No: TP1581
Synonym:
Target:
Vasonatrin Peptide (VNP) TFA
Cat.No: T78007
Synonym:
Target:
Vasonatrin Peptide (VNP)
Cat.No: TP1872
Synonym: Vasonatrin Peptide VNP
Target:
ASB20123
Cat.No: T82961
Synonym:
Target:
NPR-C activator 1
Cat.No: T61496
Synonym:
Target:
Vosoritide
Cat.No: T76277
Synonym:
Target:
Umibecestat HCl
Cat.No: T69664
Synonym:
Target:
Cenderitide
Cat.No: T76334
Synonym:
Target:
TargetMol Loading
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