|
TMPY-04404
|
DCLK1 Protein, Human, Recombinant (aa 1-705, His & GST)
doublecortin-like kinase 1,CL1,DC...
|
Human
|
Baculovirus-Insect Cells
|
|
DCAMKL1, also known as DCLK1, is a member of the protein kinase superfamily and the doublecortin family. It contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. DCA... |
|
TMPY-04752
|
DCLK1 Protein, Human, Recombinant
doublecortin-like kinase 1,CL1,D<...
|
Human
|
Baculovirus-Insect Cells
|
|
DCAMKL1, also known as DCLK1, is a member of the protein kinase superfamily and the doublecortin family. It contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. DCA... |
|
TMPY-02970
|
CXCL10 Protein, Human, Recombinant
IFI10,IP-10,chemokine (C-X-C motif) ligand...
|
Human
|
E. coli
|
|
(C-X-C motif) ligand (CXCL)10 (CXCL10) belongs to the ELR(-) CXC subfamily chemokine. CXCL10/IP-10 exerts its function through binding to chemokine (C-X-C motif) receptor 3 (CXCR3), a seven trans-membrane receptor coupled to G proteins. CXCL10/IP-10 and its receptor, CXCR3, appear to contribute to the pathogenesis of many autoimmune diseases, organ specific (such as type 1 diabetes, autoimmune thyroiditis, Graves' disease and ophthalmopathy), or systemic (such as rheumatoid arthritis, psoriatic ... |
|
TMPY-00566
|
CCL18 Protein, Human, Recombinant (His)
PARC,CCL18,CKb7,DC-CK1,chemokine ...
|
Human
|
Yeast
|
|
CCL18 is a chemotactic cytokine involved in the pathogenesis and progression of various disorders, including cancer. Proof showed high levels of CCL18 in the serum of epithelial ovarian carcinoma patients suggesting its potential as a circulating biomarker. CCL18 chemokine has an important role in chemokine-mediated tumor metastasis, and may serve as a potential predictor for poor survival outcomes for ovarian cancer. (CCL18) is predominantly secreted by M2-tumor associated macrophages (TAMs) a... |
|
TMPY-03274
|
CXCL11 Protein, Human, Recombinant
SCYB9B,I-TAC,chemokine (C-X-C motif) ligand 11<...
|
Human
|
E. coli
|
|
I-TAC, also known as CXCL11, is a small cytokine belonging to the CXC chemokine family. It is highly expressed in peripheral blood leukocytes, pancreas and liver, with moderate levels in thymus, spleen and lung and low expression levels were in small intestine, placenta and prostate. The I-TAC chemokine elicits its effects on its target cells by interacting with the cell surface chemokine receptor CXCR3, with a higher affinity than do the other ligands for this receptor, CXCL9 and CXCL10. I-TAC ... |
|
TMPY-05337
|
CXCL16 Protein, Human, Recombinant (His)
chemokine (C-X-C motif) ligand 16,CXCLG
|
Human
|
HEK293
|
|
C-X-C motif chemokine 16, also known as Small-inducible cytokine B16, SR-PSOX, and CXCL16, is a single-pass type I membrane protein which belongs to the intercrine alpha (chemokine CxC) family. CXCL16 exists in transmembrane and soluble forms. The transmembrane form acts as a scavenger receptor for oxidised LDL whereas the soluble form acts a chemoattractant for mainly CD8+ T cells. CXCL16 is a protein which shares pattern recognition receptor functions, relevant for adhesion and phagocytosis of... |
|
TMPK-00735
|
CXCL13/BCA-1 Protein, Mouse, Recombinant (His)
ANGIE,BLR1L,ANGIE2,BLC,SCYB13,BCA1
|
Mouse
|
HEK293
|
|
Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chemoattractant that activates CXCR5. Using the spinal nerve ligation (SNL) model of neuropathic pain, CXCL13 was persistently upregulated in spinal cord neurons after SNL, resulting in spinal astrocyte activation via CXCR5 in mice. |
|
TMPK-00469
|
CXCL16 Protein, Human, Recombinant (hFc)
SR-PSOX,SCYB16,CXCL16,CXCL
|
Human
|
HEK293
|
|
CXC chemokine ligand 16 (CXCL16) is a CXC soluble chemokine, an adhesion molecule and a cell surface scavenger receptor. CXCL16 regulates inflammation, tissue injury and fibrosis. Parenchymal renal cells, vascular wall cells, leukocytes and platelets express and/or release CXCL16 under the regulation of inflammatory mediators. CXCL16 expression is increased in experimental and human nephropathies. Targeting CXCL16 protected from experimental glomerular injury or interstitial fibrosis. |
|
TMPY-04984
|
CXCL17 Protein, Human, Recombinant (His)
Dcip1,UNQ473,DMC,VCC1,chemokine (C-X-C mot...
|
Human
|
Yeast
|
|
Chemokine (C-X-C motif) ligand 17 (CXCL17) is the latest member of the chemokine family. CXCL17 is a potential oncogene and promising therapeutic target, is an independent biomarker of poor prognosis in patients with breast cancer, and can promote proliferation and migration of breast cancer cells in vitro and in vivo. CXCL17 is expressed in a variety of cancers and promotes tumor progression by recruiting myeloid-derived suppressor cells (MDSCs). CXCL17 attenuates IMQ-induced psoriasis-like ski... |
|
TMPJ-00006
|
CXCL1 Protein, Mouse, Recombinant (His)
Scyb1,Growth-regulated α,Mgsa,Gro1,Growth-...
|
Mouse
|
Human Cells
|
|
Growth-regulated alpha protein (CXCL1,KC), is a member of the alpha chemokine subfamily, was initially identified as an immediate early gene induced in mouse fibroblasts by platelet-derived growth factor. The N-terminal processed form KC(5-72) of the protein is produced by proteolytic cleavage after secretion from bone marrow stromal cells, and shows a highly enhanced hematopoietic activity. Mouse KC shows approximately 63% identity to that of mouse MIP-2. KC is also approximately 60% identical ... |
|
TMPY-02180
|
CXCL1 Protein, Human, Recombinant (His & NusA)
CA21H,CPS1,CYP21,GRO1,GR...
|
Human
|
E. coli
|
|
The Chemokine (C-X-C motif) Ligand 1, CXCL1, is a small cytokine belonging to the CXC chemokine family that was previously called GRO1 oncogene, GRO?, KC, Neutrophil-activating protein 3 (NAP-3) and melanoma growth stimulating activity, alpha (MSGA-a). CXCL1 already known to be important in osteoarthritis (OA), as a novel target gene of transcription factor AP-2? in chondrocytes and support the important role of AP-2? in cartilage. CXCL1 is a potent neutrophil chemoattractant with recognized rol... |
|
TMPY-06582
|
CXCL14 Protein, Human, Recombinant (His)
SCYB14,BRAK,MIP2G,KS1,MIP-2g,chemokine (C-...
|
Human
|
E. coli
|
|
CXCL14 is a CXC chemokine family that exhibits antimicrobial activity and contains an amphipathic cationic alpha-helical region in the C-terminus, a characteristic structure of antimicrobial peptides (AMPs). CXCL14 is involved in cell recruitment, migration, activation, and homing in liver diseases and have been shown to be upregulated during acute liver injury in animal models. The CXC chemokine ligand 14 (CXCL14) had been show highly expressed in tumor-associated stromal cells, promoting tumor... |
|
TMPK-00017
|
CXCL13/BCA-1 Protein, Human, Recombinant (hFc)
BCA1,BLR1L,BLC,SCYB13,ANGIE2,BCA-...
|
Human
|
HEK293
|
|
Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chemoattractant that activates CXCR5. Using the spinal nerve ligation (SNL) model of neuropathic pain, CXCL13 was persistently upregulated in spinal cord neurons after SNL, resulting in spinal astrocyte activation via CXCR5 in mice. |
|
TMPY-03025
|
CXCL16 Protein, Rat, Recombinant (hFc)
chemokine (C-X-C motif) ligand 16
|
Rat
|
HEK293
|
|
C-X-C motif chemokine 16, also known as Small-inducible cytokine B16, SR-PSOX, and CXCL16, is a single-pass type I membrane protein which belongs to the intercrine alpha (chemokine CxC) family. CXCL16 exists in transmembrane and soluble forms. The transmembrane form acts as a scavenger receptor for oxidised LDL whereas the soluble form acts a chemoattractant for mainly CD8+ T cells. CXCL16 is a protein which shares pattern recognition receptor functions, relevant for adhesion and phagocytosis of... |
|
TMPJ-01394
|
CXCL15 Protein, Mouse, Recombinant (His)
Lungkine,C-X-C motif chemokine 15,Small-inducible c...
|
Mouse
|
Human Cells
|
|
Mouse C-X-C motif chemokine 15, also known as Cxcl15, is a secreted protein which is member of the ELR motif-containing CXC chemokines. It expressed at low levels in fetal lung, the expression restricted to the lung, produced by bronchoepithelial cells and is released into the airways. It plays an important role in lung-specific neutrophil trafficking during normal and inflammatory conditions. It also appears chemotactic for neutrophils. |
|
TMPK-00721
|
CX3CL1/Fractalkine Protein, Mouse, Recombinant (His & Avi), Biotinylated
Neurotactin,CXC3C,ABCD-3,Fkn,Fractalkine,NTT,Cx3cl<...
|
Mouse
|
HEK293
|
|
Fractalkine/CX3C chemokine ligand 1 (CX3CL1) is a chemokine involved in the anticancer function of lymphocytes-mainly NK cells, T cells and dendritic cells. Its increased levels in tumors improve the prognosis for cancer patients, although it is also associated with a poorer prognosis in some types of cancers, such as pancreatic ductal adenocarcinoma. |
|
TMPY-04943
|
CXCL10 Protein, Rat, Recombinant (His)
chemokine (C-X-C motif) ligand 10,IP-10,Sc...
|
Rat
|
Yeast
|
|
(C-X-C motif) ligand (CXCL)10 (CXCL10) belongs to the ELR(-) CXC subfamily chemokine. CXCL10/IP-10 exerts its function through binding to chemokine (C-X-C motif) receptor 3 (CXCR3), a seven trans-membrane receptor coupled to G proteins. CXCL10/IP-10 and its receptor, CXCR3, appear to contribute to the pathogenesis of many autoimmune diseases, organ specific (such as type 1 diabetes, autoimmune thyroiditis, Graves' disease and ophthalmopathy), or systemic (such as rheumatoid arthritis, psoriatic ... |
|
TMPJ-00952
|
CXCL12 Protein, Mouse, Recombinant
Sdf1,C-X-C motif chemokine 12,Thymic lymph...
|
Mouse
|
E. coli
|
|
Mouse Cxcl12 is a secreted and highly conserved protein which belongs to the intercrine alpha (chemokine CxC) family.CXCL12 is widely expressed in various organs including brain, kidney, skeletal muscle, heart, liver, and lymphoid organs. Cxcl12 activates the C-X-C chemokine receptor CXCR4 to induce a rapid and transient rise in the level of intracellular calcium ions and chemotaxis. It also binds to atypical chemokine receptor ACKR3 which activates the beta-arrestin pathway and acts as a scaven... |
|
TMPH-00485
|
CCL17 Protein, Canine, Recombinant (His & KSI)
CC chemokine TARC,Small-inducible cytokine A17,C-C ...
|
Canine
|
E. coli
|
|
CCL17 Protein, Canine, Recombinant (His & KSI) is expressed in E. coli. |
|
TMPH-01984
|
CLECL1P Protein, Human, Recombinant (His & Myc)
Putative C-type lectin-like domain family 1,DC-asso...
|
Human
|
Baculovirus
|
|
CLECL1P Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus. |
|
TMPY-05330
|
CCL19/MIP-3b Protein, Mouse, Recombinant (His)
chemokine (C-C motif) ligand 19,CKb11<...
|
Mouse
|
Baculovirus-Insect Cells
|
|
CCL19/MIP-3b Protein, Mouse, Recombinant (His) is expressed in Baculovirus-Insect Cells with His tag. The predicted molecular weight is 10.7 kDa. Accession number: O70460 |
|
TMPJ-00008
|
CXCL10 Protein, Human, Recombinant (hFc & His)
INP10,10 kDa Interferon Gamma-Induced Prot...
|
Human
|
Human Cells
|
|
Human C-X-C Motif Chemokine Ligand 10 (CXCL10) is a non-ELR chemokine secreted by various cell types, such as monocytes, endothelial cells and fibroblasts, in response to IFN-γ. CXCL10 functions via chemokine receptor CXCR3. CXCL10 has been attributed to several roles, such as chemoattraction for activated T-lymphocytes, inhibition of angiogenesis, and antitumor activity. |
|
TMPY-01269
|
CXCL16 Protein, Mouse, Recombinant (His)
CXCL16v2,b2b498Clo,SR-PSOX,Zmynd<...
|
Mouse
|
HEK293
|
|
C-X-C motif chemokine 16, also known as Small-inducible cytokine B16, SR-PSOX, and CXCL16, is a single-pass type I membrane protein which belongs to the intercrine alpha (chemokine CxC) family. CXCL16 exists in transmembrane and soluble forms. The transmembrane form acts as a scavenger receptor for oxidised LDL whereas the soluble form acts a chemoattractant for mainly CD8+ T cells. CXCL16 is a protein which shares pattern recognition receptor functions, relevant for adhesion and phagocytosis of... |
|
TMPY-02868
|
CXCL1 Protein, Human, Recombinant
chemokine (C-X-C motif) ligand 1 (melanoma growth s...
|
Human
|
E. coli
|
|
The Chemokine (C-X-C motif) Ligand 1, CXCL1, is a small cytokine belonging to the CXC chemokine family that was previously called GRO1 oncogene, GRO?, KC, Neutrophil-activating protein 3 (NAP-3) and melanoma growth stimulating activity, alpha (MSGA-a). CXCL1 already known to be important in osteoarthritis (OA), as a novel target gene of transcription factor AP-2? in chondrocytes and support the important role of AP-2? in cartilage. CXCL1 is a potent neutrophil chemoattractant with recognized rol... |
|
TMPY-02468
|
CCL14 Protein, Human, Recombinant (aa 28-93, His)
MCIF,HCC-3,CC-3,chemokine (C-C motif) ligand 14,FLJ...
|
Human
|
E. coli
|
|
CCL14 has an important biological role in other mammals by evolving under positive selection that has been lost in Ochotonidae (subgenera Pika and Lagotona). CC chemokine ligand 14, CCL14, is a human CC chemokine that is of recent interest because of its natural ability, upon proteolytic processing of the first eight NH2-terminal residues, to bind to and signal through the human immunodeficiency virus type-1 (HIV-1) co-receptor, CC chemokine receptor 5 (CCR5). Embryo implantation is a complex pr... |
|
TMPY-05618
|
CXCL14 Protein, Human, Recombinant, Biotinylated
MIP2G,BMAC,KS1,MIP-2g,chemokine (C-X-C motif) ligan...
|
Human
|
E. coli
|
|
CXCL14 is a CXC chemokine family that exhibits antimicrobial activity and contains an amphipathic cationic alpha-helical region in the C-terminus, a characteristic structure of antimicrobial peptides (AMPs). CXCL14 is involved in cell recruitment, migration, activation, and homing in liver diseases and have been shown to be upregulated during acute liver injury in animal models. The CXC chemokine ligand 14 (CXCL14) had been show highly expressed in tumor-associated stromal cells, promoting tumor... |
|
TMPY-00008
|
CXCL1 Protein, Rat, Recombinant
chemokine (C-X-C motif) ligand 1 (melanoma growth s...
|
Rat
|
E. coli
|
|
The Chemokine (C-X-C motif) Ligand 1, CXCL1, is a small cytokine belonging to the CXC chemokine family that was previously called GRO1 oncogene, GRO?, KC, Neutrophil-activating protein 3 (NAP-3) and melanoma growth stimulating activity, alpha (MSGA-a). CXCL1 already known to be important in osteoarthritis (OA), as a novel target gene of transcription factor AP-2? in chondrocytes and support the important role of AP-2? in cartilage. CXCL1 is a potent neutrophil chemoattractant with recognized rol... |
|
TMPY-02610
|
Lymphotactin/XCL1 Protein, Mouse, Recombinant (His)
SCM-1a,AI661682,chemokine (C motif) ligand...
|
Mouse
|
Baculovirus-Insect Cells
|
|
This antimicrobial gene encodes a member of the chemokine superfamily. Chemokines function in inflammatory and immunological responses, inducing leukocyte migration and activation. The encoded protein is a member of the C-chemokine subfamily, retaining only two of four cysteines conserved in other chemokines, and is thought to be specifically chemotactic for T cells. This gene and a closely related family member are located on the long arm of chromosome 1.Cancer ImmunotherapyImmune CheckpointImm... |
|
TMPJ-00673
|
CX3CL1/Fractalkine Protein, Mouse, Recombinant (His)
CXC3,Cx3c,NTN,Fkn,C3Xkine,C-X3-C motif chemokine 1,...
|
Mouse
|
Human Cells
|
|
Fractalkine(CX3CL1) is a single-pass type I membrane protein and belongs to the intercrine delta family. It consists of an extracellular NH2-terminal domain, a mucin-like stalk, a transmembrane α helix, and a short cytoplasmic tail. CX3CL1 exists in two forms: as a membrane-anchored or as a shed 80-95K glycoprotein. Soluble CX3CL1 is generated by limited proteolysis on the cell surface, and a disintegrin and metallopeptidase 10 (ADAM10) and ADAM17/tumor necrosis factor-α-converting enzyme (ADAM1... |
|
TMPY-02755
|
Lymphotactin/XCL1 Protein, Cynomolgus, Recombinant (His)
chemokine (C motif) ligand 1
|
Cynomolgus
|
Baculovirus-Insect Cells
|
|
This antimicrobial gene encodes a member of the chemokine superfamily. Chemokines function in inflammatory and immunological responses, inducing leukocyte migration and activation. The encoded protein is a member of the C-chemokine subfamily, retaining only two of four cysteines conserved in other chemokines, and is thought to be specifically chemotactic for T cells. This gene and a closely related family member are located on the long arm of chromosome 1.Cancer ImmunotherapyImmune CheckpointImm... |
|
TMPY-00090
|
SPARCL1 Protein, Mouse, Recombinant (His)
Sc1,SPARC like 1,mast9,hevin,Ecm2
|
Mouse
|
HEK293
|
|
SPARC-like protein 1 (SPARCL1; also known as SC1, high endothelial venule protein, or hevin) is an extracellular matrix-associated, secreted glycoprotein belonging to the secreted protein acidic and rich in cysteine (SPARC) family of matricellular proteins. It contains three conserved structural domains that are implicated in the regulation of cell adhesion, migration, and proliferation. SPARCL1 is expressed during embryogenesis and tissue remodeling and is especially prominent in brain and vasc... |
|
TMPH-01397
|
LANCL1 Protein, Human, Recombinant (His & Myc)
|
Human
|
E. coli
|
|
Functions as glutathione transferase. Catalyzes conjugation of the glutathione (GSH) to artificial substrates 1-chloro-2,4-dinitrobenzene (CDNB) and p-nitrophenyl acetate. Mitigates neuronal oxidative stress during normal postnatal development and in response to oxidative stresses probably through GSH antioxidant defense mechanism. May play a role in EPS8 signaling. Binds glutathione. |
|
TMPY-02026
|
CXCL1 Protein, Human, Recombinant (His & SUMO)
FSP,P450c21B,CYP21B,CAH1,GROa,SCY...
|
Human
|
E. coli
|
|
The Chemokine (C-X-C motif) Ligand 1, CXCL1, is a small cytokine belonging to the CXC chemokine family that was previously called GRO1 oncogene, GRO?, KC, Neutrophil-activating protein 3 (NAP-3) and melanoma growth stimulating activity, alpha (MSGA-a). CXCL1 already known to be important in osteoarthritis (OA), as a novel target gene of transcription factor AP-2? in chondrocytes and support the important role of AP-2? in cartilage. CXCL1 is a potent neutrophil chemoattractant with recognized rol... |
|
TMPK-00734
|
CXCL13/BCA-1 Protein, Mouse, Recombinant (hFc)
ANGIE,ANGIE2,BCA-1,BLR1L,BLC,BCA1...
|
Mouse
|
HEK293
|
|
Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chemoattractant that activates CXCR5. Using the spinal nerve ligation (SNL) model of neuropathic pain, CXCL13 was persistently upregulated in spinal cord neurons after SNL, resulting in spinal astrocyte activation via CXCR5 in mice. |
|
TMPY-03896
|
CXCL16 Protein, Canine, Recombinant (hFc)
chemokine (C-X-C motif) ligand 16
|
Canine
|
HEK293
|
|
C-X-C motif chemokine 16, also known as Small-inducible cytokine B16, SR-PSOX, and CXCL16, is a single-pass type I membrane protein which belongs to the intercrine alpha (chemokine CxC) family. CXCL16 exists in transmembrane and soluble forms. The transmembrane form acts as a scavenger receptor for oxidised LDL whereas the soluble form acts a chemoattractant for mainly CD8+ T cells. CXCL16 is a protein which shares pattern recognition receptor functions, relevant for adhesion and phagocytosis of... |
|
TMPK-00138
|
CXCL16 Protein, Mouse, Recombinant (hFc)
SR-PSOX,SCYB16,SRPSOX,CXCLG16,CX<...
|
Mouse
|
HEK293
|
|
CXC chemokine ligand 16 (CXCL16) is a CXC soluble chemokine, an adhesion molecule and a cell surface scavenger receptor. CXCL16 regulates inflammation, tissue injury and fibrosis. Parenchymal renal cells, vascular wall cells, leukocytes and platelets express and/or release CXCL16 under the regulation of inflammatory mediators. CXCL16 expression is increased in experimental and human nephropathies. Targeting CXCL16 protected from experimental glomerular injury or interstitial fibrosis. |
|
TMPY-02550
|
Eotaxin/CCL11 Protein, Human, Recombinant (His)
SCYA11,chemokine (C-C motif) ligand 1<...
|
Human
|
E. coli
|
|
CCL11 or chemokine (C-C motif) ligand 11 is a member of the chemokine (C-C motif) ligand family. Chemokin (C-C motif) ligand 11 is a member of the chemokine family. There are four members of the chemokine family: C-C kemokines, C kemokines, CXC kemokines and CX3C kemokines. The C-C kemokines have two cysteines nearby the amino terminus. There have been at least 27 distinct members of this subgroup reported for mammals, called C-C chemokine ligands (CCL)-1 to 28. Chemokines are a family of small ... |
|
TMPY-00641
|
LEC/CCL16 Protein, Human, Recombinant (His)
SCYL4,HCC-4,ILINCK,LMC,SCYA16,NCC-4,CKb12,...
|
Human
|
E. coli
|
|
CCL16, a chemokine poorly characterized at the functional level. Human CCL16 is a member of the CC family, and its gene maps to human chromosome 17q. In the mouse, only a pseudogene has been identified to date. CCL16 is a functional ligand for CCR1, CCR2, CCR5, and CCR8. Recombinant CCL16 demonstrated chemotactic activity on human monocytes and lymphocytes. Based on the ability of human chemokines to exert activity on and bind to murine receptors, the TSA mouse adenocarcinoma cell line was trans... |
|
TMPY-02687
|
Lymphotactin/XCL1 Protein, Human, Recombinant (His)
SCM1,SCM-1,SCYC1,LTN,LPTN,SCM-
|
Human
|
Baculovirus-Insect Cells
|
|
This antimicrobial gene encodes a member of the chemokine superfamily. Chemokines function in inflammatory and immunological responses, inducing leukocyte migration and activation. The encoded protein is a member of the C-chemokine subfamily, retaining only two of four cysteines conserved in other chemokines, and is thought to be specifically chemotactic for T cells. This gene and a closely related family member are located on the long arm of chromosome 1.Cancer ImmunotherapyImmune CheckpointImm... |
|
TMPY-02518
|
TCL1A Protein, Human, Recombinant (His)
TCL1,T-cell leukemia/lymphoma 1A
|
Human
|
E. coli
|
|
T-cell leukemia/lymphoma protein 1A (abbreviated for TCL1A) is a member of the TCL1 family. TCL1 protooncogene is expressed in CD3-CD4-CD8-precursor T cells and is extinguished at the CD4+CD8+stage of thymocyte development. In B cells, TCL1 is first expressed in pro-B cells and remains high in naive mantle zone B cells of peripheral lymphoid tissues. The TCL1 protooncogene is overexpressed in many mature B cell lymphomas, especially from AIDS patients. It has been demonstrated that TCL1 is a pow... |
|
TMPH-01001
|
BCL10 Protein, Human, Recombinant (His & SUMO)
B-cell lymphoma/leukemia 10,cCARMEN,hCLAP,...
|
Human
|
E. coli
|
|
Plays a key role in both adaptive and innate immune signaling by bridging CARD domain-containing proteins to immune activation. Acts by channeling adaptive and innate immune signaling downstream of CARD domain-containing proteins CARD9, CARD11 and CARD14 to activate NF-kappa-B and MAP kinase p38 (MAPK11, MAPK12, MAPK13 and/or MAPK14) pathways which stimulate expression of genes encoding pro-inflammatory cytokines and chemokines. Recruited by activated CARD domain-containing proteins: homooligome... |
|
TMPH-01099
|
CLTCL1 Protein, Human, Recombinant (His)
CLH-22,CLTD,CLTCL,CL...
|
Human
|
E. coli
|
|
Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Two different adapter protein complexes link the clathrin lattice either to the plasma membrane or to the trans-Golgi network. |
|
TMPY-03771
|
CXCL16 Protein, Canine, Recombinant (His)
chemokine (C-X-C motif) ligand 16
|
Canine
|
HEK293
|
|
C-X-C motif chemokine 16, also known as Small-inducible cytokine B16, SR-PSOX, and CXCL16, is a single-pass type I membrane protein which belongs to the intercrine alpha (chemokine CxC) family. CXCL16 exists in transmembrane and soluble forms. The transmembrane form acts as a scavenger receptor for oxidised LDL whereas the soluble form acts a chemoattractant for mainly CD8+ T cells. CXCL16 is a protein which shares pattern recognition receptor functions, relevant for adhesion and phagocytosis of... |
|
TMPY-00433
|
CXCL1 Protein, Mouse, Recombinant
Gro1,Scyb1,gro,KC,Fsp,N51,chemoki...
|
Mouse
|
E. coli
|
|
The Chemokine (C-X-C motif) Ligand 1, CXCL1, is a small cytokine belonging to the CXC chemokine family that was previously called GRO1 oncogene, GRO?, KC, Neutrophil-activating protein 3 (NAP-3) and melanoma growth stimulating activity, alpha (MSGA-a). CXCL1 already known to be important in osteoarthritis (OA), as a novel target gene of transcription factor AP-2? in chondrocytes and support the important role of AP-2? in cartilage. CXCL1 is a potent neutrophil chemoattractant with recognized rol... |
|
TMPJ-00018
|
CCL16 Protein, Human, Recombinant
NCC-4,Lymphocyte and Monocyte Chemoattractant,LMC,NCC4,HCC-4...
|
Human
|
E. coli
|
|
CCL16 is a member of CC chemokine family. CCL16 cDNA encodes a 120 amino acid peptide along with a 23 amino acids signal peptide that is cleaved to generate 97 amino acid protein. CCL16 is distantly related to other CC chemokines, showing less than 30% sequence identity. CCL16 elicits its effects on cells by interacting with cell surface chemokine receptors such as CCR1, CCR2, CCR5 and CCR8. Recombinant CCL16 has been shown to chemoattract human monocytes and THP1 cells but not resting lymphocyt... |
|
TMPY-03905
|
Lymphotactin/XCL1 Protein, Canine, Recombinant (His)
chemokine (C motif) ligand 1
|
Canine
|
Baculovirus-Insect Cells
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This antimicrobial gene encodes a member of the chemokine superfamily. Chemokines function in inflammatory and immunological responses, inducing leukocyte migration and activation. The encoded protein is a member of the C-chemokine subfamily, retaining only two of four cysteines conserved in other chemokines, and is thought to be specifically chemotactic for T cells. This gene and a closely related family member are located on the long arm of chromosome 1.Cancer ImmunotherapyImmune CheckpointImm... |
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TMPJ-00974
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XCL1 Protein, Human, Recombinant (hFc & His)
Cytokine SCM-1,Lymphotaxin,LTN,XC chemokine ligand ...
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Human
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Human Cells
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Lymphotactin is a secreted protein which belongs to the intercrine gamma family. It is also a member of the XC chemokine family. XCL1 is found in spleen with highest level, lower in peripheral leukocytes and very low levels in lung, colon and small intestine. XCL1 plays a role in inflammatory and immunological responses, inducing leukocyte migration and activation. XCL1 induces chemotactic function by binding to a chemokine receptor called XCR1. XCL1 is closely related to another chemokine calle... |
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TMPY-00573
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MUCL1 Protein, Human, Recombinant (His)
mucin like 1,SBEM
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Human
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HEK293
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MUCL1 Protein, Human, Recombinant (His) is expressed in HEK293 with His tag. The predicted molecular weight is 8.4 kDa. Accession number: Q96DR8 |
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TMPK-01269
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CXCL10 Protein, Cynomolgus, Recombinant (His)
IFI10,gIP-10,CXCL10,IP-<...
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Cynomolgus
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E. coli
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C-X-C motif ligand 10 (CXCL10), or interferon-inducible protein-10, is a small chemokine belonging to the CXC chemokine family. Its members are responsible for leukocyte trafficking and act on tissue cells, like endothelial and vascular smooth muscle cells. CXCL10 is secreted by leukocytes and tissue cells and functions as a chemoattractant, mainly for lymphocytes. |
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TMPY-00001
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CXCL14 Protein, Mouse, Recombinant
MIP2gamma,Scyb14,BMAC,MIP2γ,bolekine,AI414...
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Mouse
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E. coli
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CXCL14 is a CXC chemokine family that exhibits antimicrobial activity and contains an amphipathic cationic alpha-helical region in the C-terminus, a characteristic structure of antimicrobial peptides (AMPs). CXCL14 is involved in cell recruitment, migration, activation, and homing in liver diseases and have been shown to be upregulated during acute liver injury in animal models. The CXC chemokine ligand 14 (CXCL14) had been show highly expressed in tumor-associated stromal cells, promoting tumor... |
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