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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T10252L2 |
ADU-S100 ammonium salt
ML RR-S2 CDA ammonium salt,MIW815 ammonium salt |
STING | Immunology/Inflammation |
ADU-S100 ammonium salt (ML RR-S2 CDA ammonium salt) 是干扰素基因刺激物的激活剂。 ADU-S100 ammonium salt 可导致有效的全身性肿瘤消退和免疫。 | |||
T10252L3 |
ADU-S100
ML RR-S2 CDA,MIW815 |
Others | Others |
ADU-S100 is an activator of stimulator of interferon genes (STING). | |||
T10252 |
ADU-S100 disodium salt
ML RR-S2 CDA disodium salt,MIW815 disodium salt |
Others | Others |
ADU-S100 (MIW815) disodium salt is an activator of stimulator of interferon genes (STING). | |||
T10252L |
ADU-S100 enantiomer ammonium salt
MIW815 enantiomer ammonium salt,ML RR-S2 CDA enantiomer ammonium salt |
Others | Others |
ADU-S100 (MIW815) enantiomer ammonium salt is the less active enantiomer of ADU-S100. ADU-S100 is an activator of the stimulator of interferon genes (STING). | |||
T18880 |
BCDA
酯酶显色底物-1,5-bromo-4-chloroindoxyl acetate |
Others | Others |
BCDA (5-bromo-4-chloroindoxyl acetate) 是酯酶的显色底物,可有效检测酯酶的活性。 | |||
T65066 |
CDAP
|
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CDAP 在生命科学相关研究中具有广泛的应用。 | |||
T82271 |
Golocdacimab
MEDI6570 |
||
Golocdacimab (MEDI6570) 是一种针对LOX-1的全人源单克隆抗体,潜在可用于研究2型糖尿病。 | |||
T75396 | Sphingolipid ceramide N-deacylase (SCDase) | ||
Sphingolipid ceramide N-deacylase (SCDase) 催化糖鞘脂中的脂肪酸与鞘氨醇碱基间的N-酰基键断裂,进而生成溶血糖鞘脂。 | |||
T75378 |
DCDAPH
|
||
DCDAPH(Compound 2c)是用于β-淀粉样蛋白(Aβ)斑块检测的新型智能近红外探针,在PBS中λex/λem为597/665 nm。此化合物对Aβ具有高亲和性(Ki=37 nM,Kd=27 nM),并显示良好的血脑屏障渗透性,能够满足大多数体外及体内Aβ检测需求。 | |||
TP2369 |
Alicdamotide
|
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Alicdamotide is a bioactive chemical. | |||
T78437 |
PTCDA
|
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PTCDA,一种有机染料分子兼具有机半导体属性。 | |||
T60553 | Tetrahydrouridine dihydrate | ||
Tetrahydrouridine dihydrate (THU dihydrate) 是有效的胞苷脱氨酶抑制剂。Tetrahydrouridine dihydrate 比内在胞苷更有效地竞争性阻断酶的活性位点。 | |||
T60708 |
Cedazuridine hydrochloride
|
||
Cedazuridine (E7727) (Compound 7a) hydrochloride 是一种可用于研究癌症的,口服有效的胞苷脱氨酶 (CDA) 抑制剂 (IC 50 = 0.4 μM)。 | |||
T17059 |
Tetrahydrouridine
NSC 112907,NSC112907,四氢尿苷,NSC-112907 |
DNA Methyltransferase | Chromatin/Epigenetic |
Tetrahydrouridine (NSC-112907; THU) 是一种多药耐药调节剂。它可用于癌症治疗,使肿瘤细胞对放射治疗更加敏感。 它是一种竞争性胞苷脱氨酶 (CDA) 抑制剂,可抑制 ara-C 和吉西他滨等细胞毒性脱氧胞苷类似物分解代谢中的脱氨作用。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-01178 |
CDA Protein, Human, Recombinant (His & Myc)
CDA,Cytidine aminohydrolase,CDD,Cytidine deaminase |
Human | E. coli |
CDA Protein, Human, Recombinant (His & Myc) is expressed in E. coli. | |||
TMPH-00051 |
Chitin deacetylase Protein, Amylomyces rouxii, Recombinant (His)
Chitin deacetylase,MrCDA,CDA |
Amylomyces rouxii | E. coli |
Hydrolyzes the N-acetamido groups of N-acetyl-D-glucosamine residues in chitin to form chitosan and acetate. Chitin deacetylase Protein, Amylomyces rouxii, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 49.9 kDa and the accession number is P50325. | |||
TMPH-00607 |
Cytosine deaminase Protein, E. coli, Recombinant (His & SUMO)
CD,Cytosine deaminase,CDase,CDA,codA,Cytos... |
E. coli | E. coli |
Cytosine deaminase Protein, E. coli, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 63.5 kDa and the accession number is P25524. | |||
TMPY-01333 |
HDAC8 Protein, Human, Recombinant (GST)
histone deacetylase 8,CDA07,MRXS6,RPD3,CDLS5,WTS,HD... |
Human | Baculovirus Insect Cells |
HDAC8 Protein, Human, Recombinant (GST) is expressed in Baculovirus insect cells with GST tag. The predicted molecular weight is 68 kDa and the accession number is Q9BY41-1. | |||
TMPY-03508 |
XTP3TPA Protein, Human, Recombinant (His)
XTP3TPA,dCTP pyrophosphatase 1,RS21C6,CDA03 |
Human | E. coli |
DCTPP1 hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. It has a strong preference for modified dCTP. DCTPP1’s activity is highest with 5-iodo-dCTP, followed by 5-bromo-dCTP, unmodified dCTP, 5-methyl-dCTP and 5-chloro-dCTP. DCTPP1 also hydrolyzes 2-chloro-dATP and 2-hydroxy-dATP with lower efficiency, and has even lower activity with unmodified dATP, dTTP and dUTP (in vitro). DCTPP1 does not hydrolyze ATP, UTP, ITP, GTP, dADP, dCDP or dGTP.... | |||
TMPH-03437 |
CDA2 Protein, S. cerevisiae, Recombinant (His)
CDA2,Chitin deacetylase 2 |
Saccharomyces cerevisiae | P. pastoris (Yeast) |
Hydrolyzes the N-acetamido groups of N-acetyl-D-glucosamine residues in chitin to form chitosan and acetate. Chitosan is a component of the spore wall. CDA2 Protein, S. cerevisiae, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 34.9 kDa and the accession number is Q06703. | |||
TMPY-03065 |
BACE2 Protein, Mouse, Recombinant (His)
CEAP1,BAE2,1110059C24Rik,β-site APP-cleaving enzyme 2,CD... |
Mouse | HEK293 Cells |
BACE2, also known as beta secretase 2, belongs to the peptidase A1 family. It is a protease known to be an important enzyme involved in the cellular pathways. BACE2 has been shown to interact with GGA1 and GGA2. It is the major β-secretase in vivo. BACE2 is located on chromosome 21 and may play a role in alzheimer's disease pathogenesis in down syndrome(DS). Overexpression of BACE2 by lentivirus markedly reduced amyloid β protein production in primary neurons. Despite an extra copy of the BACE2 ... | |||
TMPH-02908 |
AICDA Protein, Mouse, Recombinant (His & Myc)
Single-stranded DNA cytosine deaminase,Cytidine aminohydrola... |
Mouse | E. coli |
Single-stranded DNA-specific cytidine deaminase. Involved in somatic hypermutation (SHM), gene conversion, and class-switch recombination (CSR) in B-lymphocytes by deaminating C to U during transcription of Ig-variable (V) and Ig-switch (S) region DNA. Required for several crucial steps of B-cell terminal differentiation necessary for efficient antibody responses. May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation. |