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Targets Recommended: STING

14

抑制剂 & 化合物

8

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T10252L2 ADU-S100 ammonium salt

ML RR-S2 CDA ammonium salt,MIW815 ammonium salt

STING Immunology/Inflammation
ADU-S100 ammonium salt (ML RR-S2 CDA ammonium salt) 是干扰素基因刺激物的激活剂。 ADU-S100 ammonium salt 可导致有效的全身性肿瘤消退和免疫。
T10252L3 ADU-S100

ML RR-S2 CDA,MIW815

Others Others
ADU-S100 is an activator of stimulator of interferon genes (STING).
T10252 ADU-S100 disodium salt

ML RR-S2 CDA disodium salt,MIW815 disodium salt

Others Others
ADU-S100 (MIW815) disodium salt is an activator of stimulator of interferon genes (STING).
T10252L ADU-S100 enantiomer ammonium salt

MIW815 enantiomer ammonium salt,ML RR-S2 CDA enantiomer ammonium salt

Others Others
ADU-S100 (MIW815) enantiomer ammonium salt is the less active enantiomer of ADU-S100. ADU-S100 is an activator of the stimulator of interferon genes (STING).
T18880 BCDA

酯酶显色底物-1,5-bromo-4-chloroindoxyl acetate

Others Others
BCDA (5-bromo-4-chloroindoxyl acetate) 是酯酶的显色底物,可有效检测酯酶的活性。
T65066 CDAP

CDAP 在生命科学相关研究中具有广泛的应用。
T82271 Golocdacimab

MEDI6570

Golocdacimab (MEDI6570) 是一种针对LOX-1的全人源单克隆抗体,潜在可用于研究2型糖尿病。
T75396 Sphingolipid ceramide N-deacylase (SCDase)

Sphingolipid ceramide N-deacylase (SCDase) 催化糖鞘脂中的脂肪酸与鞘氨醇碱基间的N-酰基键断裂,进而生成溶血糖鞘脂。
T75378 DCDAPH

DCDAPH(Compound 2c)是用于β-淀粉样蛋白(Aβ)斑块检测的新型智能近红外探针,在PBS中λex/λem为597/665 nm。此化合物对Aβ具有高亲和性(Ki=37 nM,Kd=27 nM),并显示良好的血脑屏障渗透性,能够满足大多数体外及体内Aβ检测需求。
TP2369 Alicdamotide

Alicdamotide is a bioactive chemical.
T78437 PTCDA

PTCDA,一种有机染料分子兼具有机半导体属性。
T60553 Tetrahydrouridine dihydrate

Tetrahydrouridine dihydrate (THU dihydrate) 是有效的胞苷脱氨酶抑制剂。Tetrahydrouridine dihydrate 比内在胞苷更有效地竞争性阻断酶的活性位点。
T60708 Cedazuridine hydrochloride

Cedazuridine (E7727) (Compound 7a) hydrochloride 是一种可用于研究癌症的,口服有效的胞苷脱氨酶 (CDA) 抑制剂 (IC 50 = 0.4 μM)。
T17059 Tetrahydrouridine

NSC 112907,NSC112907,四氢尿苷,NSC-112907

DNA Methyltransferase Chromatin/Epigenetic
Tetrahydrouridine (NSC-112907; THU) 是一种多药耐药调节剂。它可用于癌症治疗,使肿瘤细胞对放射治疗更加敏感。 它是一种竞争性胞苷脱氨酶 (CDA) 抑制剂,可抑制 ara-C 和吉西他滨等细胞毒性脱氧胞苷类似物分解代谢中的脱氨作用。

化合物

ADU-S100 ammonium salt
Cat.No: T10252L2
Synonym: ML RR-S2 CDA ammonium salt,MIW815 ammonium salt
Target: STING
ADU-S100
Cat.No: T10252L3
Synonym: ML RR-S2 CDA,MIW815
Target: Others
ADU-S100 disodium salt
Cat.No: T10252
Synonym: ML RR-S2 CDA disodium salt,MIW815 disodium salt
Target: Others
ADU-S100 enantiomer ammonium salt
Cat.No: T10252L
Synonym: MIW815 enantiomer ammonium salt,ML RR-S2 CDA enantiomer ammonium salt
Target: Others
BCDA
Cat.No: T18880
Synonym: 酯酶显色底物-1,5-bromo-4-chloroindoxyl acetate
Target: Others
CDAP
Cat.No: T65066
Synonym:
Target:
Golocdacimab
Cat.No: T82271
Synonym: MEDI6570
Target:
Sphingolipid ceramide N-deacylase (SCDase)
Cat.No: T75396
Synonym:
Target:
DCDAPH
Cat.No: T75378
Synonym:
Target:
Alicdamotide
Cat.No: TP2369
Synonym:
Target:
PTCDA
Cat.No: T78437
Synonym:
Target:
Tetrahydrouridine dihydrate
Cat.No: T60553
Synonym:
Target:
Cedazuridine hydrochloride
Cat.No: T60708
Synonym:
Target:
Tetrahydrouridine
Cat.No: T17059
Synonym: NSC 112907,NSC112907,四氢尿苷,NSC-112907
Target: DNA Methyltransferase
Cat. No. Product Name Species Expression System
TMPH-01178 CDA Protein, Human, Recombinant (His & Myc)

CDA,Cytidine aminohydrolase,CDD,Cytidine deaminase

Human E. coli
CDA Protein, Human, Recombinant (His & Myc) is expressed in E. coli.
TMPH-00051 Chitin deacetylase Protein, Amylomyces rouxii, Recombinant (His)

Chitin deacetylase,MrCDA,CDA

Amylomyces rouxii E. coli
Hydrolyzes the N-acetamido groups of N-acetyl-D-glucosamine residues in chitin to form chitosan and acetate. Chitin deacetylase Protein, Amylomyces rouxii, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 49.9 kDa and the accession number is P50325.
TMPH-00607 Cytosine deaminase Protein, E. coli, Recombinant (His & SUMO)

CD,Cytosine deaminase,CDase,CDA,codA,Cytos...

E. coli E. coli
Cytosine deaminase Protein, E. coli, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 63.5 kDa and the accession number is P25524.
TMPY-01333 HDAC8 Protein, Human, Recombinant (GST)

histone deacetylase 8,CDA07,MRXS6,RPD3,CDLS5,WTS,HD...

Human Baculovirus Insect Cells
HDAC8 Protein, Human, Recombinant (GST) is expressed in Baculovirus insect cells with GST tag. The predicted molecular weight is 68 kDa and the accession number is Q9BY41-1.
TMPY-03508 XTP3TPA Protein, Human, Recombinant (His)

XTP3TPA,dCTP pyrophosphatase 1,RS21C6,CDA03

Human E. coli
DCTPP1 hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. It has a strong preference for modified dCTP. DCTPP1’s activity is highest with 5-iodo-dCTP, followed by 5-bromo-dCTP, unmodified dCTP, 5-methyl-dCTP and 5-chloro-dCTP. DCTPP1 also hydrolyzes 2-chloro-dATP and 2-hydroxy-dATP with lower efficiency, and has even lower activity with unmodified dATP, dTTP and dUTP (in vitro). DCTPP1 does not hydrolyze ATP, UTP, ITP, GTP, dADP, dCDP or dGTP....
TMPH-03437 CDA2 Protein, S. cerevisiae, Recombinant (His)

CDA2,Chitin deacetylase 2

Saccharomyces cerevisiae P. pastoris (Yeast)
Hydrolyzes the N-acetamido groups of N-acetyl-D-glucosamine residues in chitin to form chitosan and acetate. Chitosan is a component of the spore wall. CDA2 Protein, S. cerevisiae, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 34.9 kDa and the accession number is Q06703.
TMPY-03065 BACE2 Protein, Mouse, Recombinant (His)

CEAP1,BAE2,1110059C24Rik,β-site APP-cleaving enzyme 2,CD...

Mouse HEK293 Cells
BACE2, also known as beta secretase 2, belongs to the peptidase A1 family. It is a protease known to be an important enzyme involved in the cellular pathways. BACE2 has been shown to interact with GGA1 and GGA2. It is the major β-secretase in vivo. BACE2 is located on chromosome 21 and may play a role in alzheimer's disease pathogenesis in down syndrome(DS). Overexpression of BACE2 by lentivirus markedly reduced amyloid β protein production in primary neurons. Despite an extra copy of the BACE2 ...
TMPH-02908 AICDA Protein, Mouse, Recombinant (His & Myc)

Single-stranded DNA cytosine deaminase,Cytidine aminohydrola...

Mouse E. coli
Single-stranded DNA-specific cytidine deaminase. Involved in somatic hypermutation (SHM), gene conversion, and class-switch recombination (CSR) in B-lymphocytes by deaminating C to U during transcription of Ig-variable (V) and Ig-switch (S) region DNA. Required for several crucial steps of B-cell terminal differentiation necessary for efficient antibody responses. May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation.

重组蛋白

CDA Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-01178
Species: Human
Expression System: E. coli
Chitin deacetylase Protein, Amylomyces rouxii, Recombinant (His)
Cat.No: TMPH-00051
Species: Amylomyces rouxii
Expression System: E. coli
Cytosine deaminase Protein, E. coli, Recombinant (His & SUMO)
Cat.No: TMPH-00607
Species: E. coli
Expression System: E. coli
HDAC8 Protein, Human, Recombinant (GST)
Cat.No: TMPY-01333
Species: Human
Expression System: Baculovirus Insect Cells
XTP3TPA Protein, Human, Recombinant (His)
Cat.No: TMPY-03508
Species: Human
Expression System: E. coli
CDA2 Protein, S. cerevisiae, Recombinant (His)
Cat.No: TMPH-03437
Species: Saccharomyces cerevisiae
Expression System: P. pastoris (Yeast)
BACE2 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-03065
Species: Mouse
Expression System: HEK293 Cells
AICDA Protein, Mouse, Recombinant (His & Myc)
Cat.No: TMPH-02908
Species: Mouse
Expression System: E. coli
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