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Search Results for " calm "

Targets Recommended: Apoptosis Histone Methyltransferase

15

抑制剂 & 化合物

1

天然产物

6

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T8838	CCI-007	Apoptosis; Histone Methyltransferase	Apoptosis; Chromatin/Epigenetic
	CCI 007 是一种具有细胞毒性的选择性白血病抑制剂，在MLL 重排的敏感系婴幼儿白血病细胞中，IC50为2.5-6.2 μM。
T18934	Calmagite	Others	Others
	Calmagite 是络合指示剂，可用于多种样品中的钙和镁的检测。
TP1271L	Calmodulin-Dependent Protein Kinase II 290-309 acetate Calmodulin-Dependent Protein Kinase II 290-309 acetate (115044-69-4 Free base)	CaMK	Neuroscience
	Calmodulin-Dependent Protein Kinase II 290-309 acetate 是 Ca2+/calmodulin-dependent protein kinase II 的有效拮抗剂（IC50 = 52 nM）。
T10667	Calmidazolium chloride R 24571,钙调蛋白抑制剂	CaMK; Autophagy	Autophagy; Neuroscience
	Calmidazolium chloride (R 24571) 是一种钙调蛋白拮抗剂，对CaM 依赖性磷酸二酯酶和钙调蛋白诱导的红细胞Ca2+转运ATP 酶活化有拮抗作用，IC50分别为0.15和0.35 μM。Calmidazolium chloride 结合CaMK 的Kd 值为3 nM。Calmidazolium chloride 在抗癌领域有研究的价值。
TP1271	Calmodulin-Dependent Protein Kinase II (290-309) Calmodulin-Dependent Protein Kinase II(290-309)
	Calmodulin-Dependent Protein Kinase II (290-309) is a potent CaMK antagonist with an IC50 of 52 nM for inhibition of Ca2+/calmodulin-dependent protein kinase II.
TP1716	Calmodulin-Dependent Protein Kinase II (281-309) Calmodulin-Dependent Protein Kinase II 281-309
	Calmodulin-Dependent Protein Kinase II (281-309) is a synthetic peptide that can be phosphorylated at Thr286 by PKC and inhibits CaM kinase II (IC50 = 80 nM).
T76487	Calmodulin Dependent Protein Kinase Substrate Analog
	CalmodulinDependent Protein Kinase Substrate Analog 是一种 Ca2+- 和钙调蛋白 (CaM) 依赖性蛋白激酶 (CaMK) 底物肽。CalmodulinDependent Protein Kinase Substrate Analog 是一种合成蛋白激酶的肽底物。
TP1710	Calmodulin Binding Peptide 1
	Calmodulin Binding Peptide 1, a potent CaM-binding peptide with picomolar (pM) affinity, originates from smooth muscle myosin light-chain kinase (MLCK peptide). It effectively blocks inositol trisphosphate (IP3)-induced calcium (Ca2+) release [1].
T40895	Calmodulin antagonist-1
	Calmodulin antagonist-1 (W-7) is a calmodulin (CaM) antagonist that effectively inhibits calmodulin-activated Ca 2+ -phosphodiesterase (PDE) with an IC 50 of 28 μM. This compound also competitively inhibits trypsin-treated Ca 2+ -PDE with respect to cyclic GMP, exhibiting an IC 50 of 375 μM and a K i value of 300 μM.
T68260	Calmidazolium (cation)
	Calmidazolium (cation) is a powerful inhibitor of or red blood cell Ca -ATPase & Ca transport into inside-out red blood cell vesicles; an antagonist of calmodulin.
T80549	Calmodulin Kinase IINtide, Myristoylated Myr-CaMKIINtide	CaMK	Neuroscience
	Myristoylated Calmodulin Kinase IINtide（Myr-CaMKIINtide）是一种选择性非竞争性CaMKII抑制剂。
T25037	Aldecalmycin
	Aldecalmycin is a new antimicrobial antibiotic isolated from Streptomyces.
T75959	Calmodulin-Dependent Protein Kinase II(290-309) acetate
	Calmodulin-Dependent Protein Kinase II (290-309) acetate 是有效的 CaMK 拮抗剂，抑制抑制 Ca2+/钙调蛋白依赖性蛋白激酶II 的IC50值为52 nM。
T76488	Calmodulin Dependent Protein Kinase Substrate
	CalmodulinDependent Protein Kinase Substrate 为Ca2+及钙调蛋白(CaM)依赖的CaMK底物肽，属合成肽底物类。
T8856	Ascorbyl Propyl Hyaluronate	Others	Others
	Ascorbyl Propyl Hyaluronate 是透明质酸和维生素 C 的完美结合，克服了维生素 C 的不稳定性，是改善皱纹、滋润、镇静肌肤、美白的优质原料。

化合物

Cat.No: T8838

Target: Apoptosis, Histone Methyltransferase

Cat.No: T18934

Target: Others

Calmodulin-Dependent Protein Kinase II 290-309 acetate

Cat.No: TP1271L

Synonym: Calmodulin-Dependent Protein Kinase II 290-309 acetate (115044-69-4 Free base)

Target: CaMK

Calmidazolium chloride

Cat.No: T10667

Synonym: R 24571,钙调蛋白抑制剂

Target: CaMK, Autophagy

Calmodulin-Dependent Protein Kinase II (290-309)

Cat.No: TP1271

Synonym: Calmodulin-Dependent Protein Kinase II(290-309)

Calmodulin-Dependent Protein Kinase II (281-309)

Cat.No: TP1716

Synonym: Calmodulin-Dependent Protein Kinase II 281-309

Calmodulin Dependent Protein Kinase Substrate Analog

Cat.No: T76487

Calmodulin Binding Peptide 1

Cat.No: TP1710

Calmodulin antagonist-1

Cat.No: T40895

Calmidazolium (cation)

Cat.No: T68260

Calmodulin Kinase IINtide, Myristoylated

Cat.No: T80549

Synonym: Myr-CaMKIINtide

Target: CaMK

Cat.No: T25037

Calmodulin-Dependent Protein Kinase II(290-309) acetate

Cat.No: T75959

Calmodulin Dependent Protein Kinase Substrate

Cat.No: T76488

Ascorbyl Propyl Hyaluronate

Cat.No: T8856

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
TN1098	Ginsenoside Rd2 人参皂苷Rd2,Ginsenoside Rd2 (Quinquenoside L10)	Others	Others
	Ginsenoside Rd2 (Quinquenoside L10) is a natural product with Nourish the strong, calm the mind, nourish the body.

天然产物

Ginsenoside Rd2

Cat.No: TN1098

Synonym: 人参皂苷Rd2,Ginsenoside Rd2 (Quinquenoside L10)

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-00029	CALM1 Protein, Human, Recombinant Calmodulin,CAMIII,CAMC,CALM,CALML...	Human	E. coli
	Calmodulin (CaM) is a multifunctional intermediate calcium-binding messenger protein expressed in all eukaryotic cells. It is an intracellular target of the secondary messenger Ca2+, and the binding of Ca2+ is required for the activation of Calmodulin. Once bound to Ca2+, Calmodulin acts as part of a calcium signal transduction pathway by modifying its interactions with various target proteins such as kinases or phosphatases. Calmodulin is a small, highly conserved protein that is 148 amino acid...
TMPY-03384	CALM2 Protein, Human, Recombinant (His) caM,calmodulin 2 (phosphorylase kinase, delta),PHKD...	Human	E. coli
	Calmodulin 2, also known as CALM2, is a calmodulin. Calmodulin 2 mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). It is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis. Calmodulin 2 gene may be a genetic determinant of hip osteoarthritis (OA). OA is a degenerative disease characterized by gradual loss of articular cartilage and is a leading cause of disability in elderly populations. CALM2 was most...
TMPY-01953	CALML5 Protein, Human, Recombinant (His & GST) calmodulin like 5,CLSP	Human	E. coli
	Calmodulin-like protein 5, also known as Calmodulin-like skin protein, CALML5 and CLSP, is a protein which contains fourEF-hand domains. CALML5 / CLSP is particularly abundant in the epidermis where its expression is directly related to keratinocyte differentiation.The expression is very low in lung. CALML5 / CLSP binds calcium. It may be involved in terminal differentiation of keratinocytes. Coxsackievirus and adenovirus receptor (CAR) is a member of the immunoglobulin (Ig) superfamily a...
TMPJ-00664	Calmegin Protein, Human, Recombinant (His) Calmegin,CLGN	Human	HEK293 Cells
	Calmegin (CLGN) is a member of the calreticulin family. Calmegin is a testis-specific endoplasmic reticulum chaperone protein. The functions during spermatogenesis as a chaperone for a range of client proteins that is important for sperm adhesion onto the egg zona pellucida and for subsequent penetration of the zona pellucida. It is required for normal male fertility, normal sperm migration from the uterus into the oviduct. Calmegin binds calcium ions and interacts with PDILT. Calmegin may play ...
TMPY-02760	CALML3 Protein, Human, Recombinant (His) calmodulin-like 3,CLP	Human	E. coli
	Calmodulin-like protein 3 (CALML3) is similar to that of authentic calmodulin and may actually compete with calmodulin by binding, with different affinity, to cellular substrates. Calmodulin-like protein 3 (CALML3) is a tumor-sensitive protein specifically expressed in normal epithelial cells but downregulated in tumorigenesis. Downregulation of the protein is an early event in breast cancer development. One of the most pressing questions raised by the discovery of CLP/CALML3 is that of its pote...
TMPJ-00939	CTH Protein, Human, Recombinant γ-Cystathionase,Cystathionine γ-Lyase,Cystathionine Gamma-Ly...	Human	E. coli
	Cystathionine Gamma-Lyase (CTH) belongs to the trans-sulfuration enzymes family. CTH exists as a homotetramer and interacts with CALM in a calcium-dependent manner. CTH breaks down cystathionine into cysteine, ammonia and 2-oxobutanoate. CTH catalyzes the last step in the trans-sulfuration pathway from methionine to cysteine and has broad substrate specificity. Defects in CTH will lead to cystathioninuria, which is an autosomal recessive phenotype characterized by abnormal accumulation of plasma...

重组蛋白

CALM1 Protein, Human, Recombinant

Cat.No: TMPJ-00029

Species: Human

Expression System: E. coli

CALM2 Protein, Human, Recombinant (His)

Cat.No: TMPY-03384

Species: Human

Expression System: E. coli

CALML5 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-01953

Species: Human

Expression System: E. coli

Calmegin Protein, Human, Recombinant (His)

Cat.No: TMPJ-00664

Species: Human

Expression System: HEK293 Cells

CALML3 Protein, Human, Recombinant (His)

Cat.No: TMPY-02760

Species: Human

Expression System: E. coli

CTH Protein, Human, Recombinant

Cat.No: TMPJ-00939

Species: Human

Expression System: E. coli

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