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Search Results for " bdh "

Targets Recommended: Apoptosis Glutathione Peroxidase Autophagy

2

抑制剂 & 化合物

1

天然产物

2

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T12189	NBDHEX	Apoptosis; Glutathione Peroxidase; Autophagy	Apoptosis; Autophagy; Metabolism
	NBDHEX 是一种谷胱甘肽 S-转移酶 P1-1 抑制剂，也是晚期自噬抑制剂。它诱导肿瘤细胞凋亡，通过抑制 GST 的催化活性，避免抑制剂被特异性泵从细胞中排出，以及破坏 GSTP1-1和关键信号传导因子之间的相互作用，从而起到抗癌的作用。
T26750	BBDHQ
	BBDHQ is a selective inhibitor of MAO-B.

化合物

Cat.No: T12189

Target: Apoptosis, Glutathione Peroxidase, Autophagy

Cat.No: T26750

Cat. No.	Product Name	Target	Signaling Pathways
T1284	Megestrol acetate SC10363,醋酸甲地孕酮,BDH1298	Glucocorticoid Receptor; Estrogen/progestogen Receptor; Progesterone Receptor; HIV Protease; Autophagy	Autophagy; Endocrinology/Hormones; Microbiology/Virology; Others; Proteases/Proteasome
	Megestrol acetate (BDH1298) 是具有口服活性的合成孕激素。它还具有抗雄激素特性，可用于治疗厌食症和恶病质。

天然产物

Megestrol acetate

Cat.No: T1284

Synonym: SC10363,醋酸甲地孕酮,BDH1298

Target: Glucocorticoid Receptor, Estrogen/progestogen Receptor, Progesterone Receptor, HIV Protease, Autophagy

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-01075	BDH1 Protein, Human, Recombinant (His) D-β-Hydroxybutyrate Dehydrogenase Mitochondrial,D-Beta-Hydro...	Human	E. coli
	D-Beta-Hydroxybutyrate Dehydrogenase Mitochondrial (BDH) is a member of the short-chain dehydrogenases/reductases (SDR) family. BDH is localized in the mitochondrion matrix. BDH forms a homotetrameric lipid-requiring enzyme of the mitochondrial membrane and has a specific necessity for phosphatidylcholine for optimal enzymatic activity. BDH catalyzes the interconversion of acetoacetate and (R)-3-hydroxybutyrate, the 2 main ketone bodies formed during fatty acid catabolism.
TMPJ-00463	BDH2 Protein, Human, Recombinant (His) Oxidoreductase UCPA,Dehydrogenase/Reductase SDR Family Membe...	Human	E. coli
	3-Hydroxybutyrate Dehydrogenase Type 2 belongs to the short-chain dehydrogenases/reductases (SDR) family. 3-Hydroxybutyrate Dehydrogenase Type 2 may play an important role in the peripheral utilization of 3-hydroxybutyrate. The cytoplasmic localization with its high ratio of oxidized NAD+, the NAD+ dependence and the kinetic parameters of 3-Hydroxybutyrate Dehydrogenase Type 2 make it suitable to conbert high levels of circulating 3-hydroxybutyrate into acetoacetate.

重组蛋白

BDH1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01075

Species: Human

Expression System: E. coli

BDH2 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00463

Species: Human

Expression System: E. coli

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