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Search Results for " aristolactam "

1

抑制剂 & 化合物

12

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T61827	RJ-34
	RJ-34, an aristolactam analogue, demonstrates strong antitumor effects across a wide range of cancer cell lines, with subnanomolar GI 50 values (GI 50 <0.1 nM) observed for A431, MES-SA, MES-SA/DX5, HCT-15, and HCT-15/CLO2 cells [1].

化合物

Cat.No: T61827

Cat. No.	Product Name	Target	Signaling Pathways
T3S1227	Aristolactam I Aristolactam,Aristololactam I,马兜铃内酰胺I,Aristololactum	Apoptosis; Caspase	Apoptosis; Proteases/Proteasome
	Aristolactam I (Aristololactum) 是马兜铃酸 I (AA-I) 的主要代谢产物，参与导致肾损伤的过程。它具有细胞毒性，通过诱导半胱天冬酶 3 依赖性途径中的细胞凋亡介导。
TN3443	Aristolactam AII	PAFR	GPCR/G Protein
	Aristolactam AII has cytotoxic activity, it also shows platelet aggregation inhibitory activity.
TN6034	Aristolactam AIa
	Aristolactam AIa 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN6034，CAS号为 97399-90-1。
TL0017	Aristolactam AIIIa	MAPK; CDK	Cell Cycle/Checkpoint; MAPK
	Aristolactam AIIIa is a new type of Plk1 inhibitors, targeting the Polo Box domain (PBD), it has anti-tumor activity. Aristolactam IIIa shows inhibition of platelet aggregation induced by collagen or arachidonic acid.
TN3446	Aristolactam FI	Others	Others
	Aristolactam FI shows platelet aggregation inhibitory activity.It is a potential cancer chemotherapeutic and chemopreventive agent.
TN3445	Aristolactam BIII	PAFR	GPCR/G Protein
	Aristolactam BIII possesses anti-platelet aggregation activity in vitro, it also shows significant cytotoxic activity (IC50 values < 4 microg/mL) against P-388, HT-29 and A549 cell lines in vitro.
TN3444	Aristolactam BII	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Aristolactam BII exhibits antimicrobial and antiinflammatory activity, it shows significant activity towards DPPH radical scavenging and potent inhibitory effects against tyrosinase mushroom. Aristolactam BII also exerts its significant neuroprotective ef
TN6118	Aristolactam IIIa N-β-glucoside
	Aristolactam IIIa N-β-glucoside 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN6118，CAS号为 80311-26-8。
TJS1226	7-(deoxyadenosin-N(6)-yl)aristolactam I	Others	Others
	7-(deoxyadenosin-N(6)-yl)aristolactam I是一种来自马兜铃草药的天然化合物。
T82970	Aristolactam A III Aristololactam A III
	Aristolactam A III (Aristololactam A III) 为一生物碱，具潜在细胞毒性，并可从鱼腥草中分离。
T83229	9-Methoxyaristolactam I
	9-Methoxyaristolactam I为一自Asarum sieboldii Miq. var. Seoulense Nakai根部提取的天然化合物。
T16846	Sauristolactam Saurolactam	Others	Others
	Sauristolactam inhibits the receptor activator of nuclear factor-κB ligand (RANKL)-induced osteoclastogenesis and has the potential to inhibit osteoclast differentiation. Sauristolactam, a natural aristolactam isolated from aerial portions of Saururus Chi

天然产物

Aristolactam I

Cat.No: T3S1227

Synonym: Aristolactam,Aristololactam I,马兜铃内酰胺I,Aristololactum

Target: Apoptosis, Caspase

Aristolactam AII

Cat.No: TN3443

Target: PAFR

Aristolactam AIa

Cat.No: TN6034

Aristolactam AIIIa

Cat.No: TL0017

Target: MAPK, CDK

Aristolactam FI

Cat.No: TN3446

Target: Others

Aristolactam BIII

Cat.No: TN3445

Target: PAFR

Aristolactam BII

Cat.No: TN3444

Target: HIV Protease

Aristolactam IIIa N-β-glucoside

Cat.No: TN6118

7-(deoxyadenosin-N(6)-yl)aristolactam I

Cat.No: TJS1226

Target: Others

Aristolactam A III

Cat.No: T82970

Synonym: Aristololactam A III

9-Methoxyaristolactam I

Cat.No: T83229

Cat.No: T16846

Synonym: Saurolactam

Target: Others

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