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Search Results for " aldh1 "

Targets Recommended: Dehydrogenase

9

抑制剂 & 化合物

1

天然产物

5

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T10140	4-Diethylaminobenzaldehyde	Dehydrogenase	Metabolism
	4-Diethylaminobenzaldehyde 是醛脱氢酶(ALDHs)的可逆抑制剂，对 ALDH1 的 Ki 为 4 nM，具有较强的抗雄激素作用，IC50为1.71 μM。
T64347	ALDH1A3-IN-3	Dehydrogenase	Metabolism
	ALDH1A3-IN-3 (化合物 16) 是一种有效的 ALDH1A3 抑制剂，IC50 值为 0.26 μM。ALDH1A3-IN-3 也是 ALDH3A1 的底物。ALDH1A3-IN-3 可用于前列腺癌的研究。
T63341	ALDH1A1-IN-2	Dehydrogenase	Metabolism
	ALDH1A1-IN-2 是一种有效的醛脱氢酶 1a1 (aldh1a1) 抑制剂，具有抗癌活性。ALDH1A1-IN-2 可用于研究乳腺癌、炎症或肥胖症。
T60240	ALDH1A3-IN-2	Dehydrogenase	Metabolism
	ALDH1A3-IN-2 是一种有效的 ALDH1A3 抑制剂，IC50 为 0.30 μM。ALDH1A3-IN-2 具有癌症疾病研究的潜力。
T60550	ALDH1A3-IN-1
	ALDH1A3-IN-1 (Compound 14) 是有效的 ALDH1A3抑制剂，可用于前列腺癌的研究， (IC50 = 0.63 μM; Ki = 0.46 μM)。
T64228	ALDH1A1-IN-3
	ALDH1A1-IN-3 是一种良好的、选择性的醛脱氢酶 1A1 (ALDH1A1) 抑制剂 (IC50: μM)。ALDH1A1-IN-3 可以有效的改善 HepG2 细胞的葡萄糖消耗。ALDH1A1-IN-3 能够用于进行改善糖代谢的研究。
T39675	ALDH1A2-IN-1 ALDH1A2-IN-1
	ALDH1A2-IN-1 is a reversible inhibitor of the active site of ALDH1A2, showing a significant affinity for the enzyme with an IC50 value of 0.91 μM and a Kd value of 0.26 μM. This compound interacts hydrophobically with the enzyme, contributing to its inhibitory properties.
T24079	GA11 GA 11,GA-11
	GA11is an inhibitor of ALDH1. It also displays anti-GBM effects in vitro and in vivo.
T72548	IGUANA-1 free base STL5-T-0057
	IGUANA-1 free base (STL5-T-0057) 作为ALDH1B1的选择性抑制剂，IC50值达30 nM。在不同条件下，对SW480细胞的生长抑制显示出显著效果，附着状态下IC50值为2.46 μM，而在球形状态下为0.39 μM。因此，IGUANA-1 free base适用于癌症相关研究。

化合物

4-Diethylaminobenzaldehyde

Cat.No: T10140

Target: Dehydrogenase

Cat.No: T64347

Target: Dehydrogenase

Cat.No: T63341

Target: Dehydrogenase

Cat.No: T60240

Target: Dehydrogenase

Cat.No: T60550

Cat.No: T64228

Cat.No: T39675

Synonym: ALDH1A2-IN-1

Cat.No: T24079

Synonym: GA 11,GA-11

IGUANA-1 free base

Cat.No: T72548

Synonym: STL5-T-0057

Cat. No.	Product Name	Target	Signaling Pathways
T2901	Daidzin NPI-031D,大豆苷,Daidzein 7-O-glucoside,Daidzoside,黄豆苷,Daidzein 7-glucoside	Dehydrogenase; Reverse Transcriptase; Mitochondrial Metabolism	Metabolism; Microbiology/Virology
	Daidzin (Daidzoside) 是从大豆中分离出来的一种异黄酮，具有抗氧化、抗癌和抗动脉粥样硬化的活性。

天然产物

Cat.No: T2901

Synonym: NPI-031D,大豆苷,Daidzein 7-O-glucoside,Daidzoside,黄豆苷,Daidzein 7-glucoside

Target: Dehydrogenase, Reverse Transcriptase, Mitochondrial Metabolism

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-01583	ALDH1A1 Protein, Human, Recombinant (His) ALDH11,ALDC,PUMB1,AL...	Human	E. coli
	Aldehyde dehydrogenase 1 family, member A1 (ALDH1A1), also known as Aldehyde dehydrogenase 1 (ALDH1), or Retinaldehyde Dehydrogenase 1 (RALDH1), is an enzyme that is expressed at high levels in stem cells and that has been suggested to regulate stem cell function. The retinaldehyde dehydrogenase (RALDH) subfamily of ALDHs, composed of ALDH1A1, ALDH1A2, ALDH1A3, and ALDH8A1, regulate development by catalyzing retinoic acid biosynthesis. The ALDH1A1 protein belongs to the aldehyde dehydrogenases f...
TMPJ-00710	ALDH1A2 Protein, Human, Recombinant (His) RALDH(II),Retinal dehydrogenase 2,RALDH2,<...	Human	E. coli
	Aldehyde dehydrogenase 1 family member A2 (ALDH1A2), also known as retinaldehyde dehydrogenase 2 (RALDH2), belongs to the aldehyde dehydrogenase family which contains two members, the ALDH1 s (ALDH1A1, ALDH1A2 and ALDH1A3) and the 9-cis retinaldehyde dehydrogenase ALDH8 s. ALDH1A2 is key enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. RA is a paracrine hormone signaling molecule that functions in developing and adult tissues. ALDH1A2 was also found to regulate norma...
TMPY-01899	ALDH1A3 Protein, Human, Recombinant (His) ALDH6,aldehyde dehydrogenase 1 family, mem...	Human	E. coli
	ALDH1A3 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 57 kDa and the accession number is A0A024RC95.
TMPY-06352	ALDH1A3 Protein, Mouse, Recombinant (His) RALDH3,ALDH6,aldehyde dehydrogenase 1<...	Mouse	E. coli
	ALDH1A3 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 56.94 kDa and the accession number is Q9JHW9.
TMPY-04318	GRIK2 Protein, Human, Recombinant (hFc) GLUR6,EAA4,MRT6,GLR6,glutamate receptor, ionotropic, kainate...	Human	HEK293 Cells
	GRIK2 (Glutamate Ionotropic Receptor Kainate Type Subunit 2, also known as GluR6) is a Protein Coding gene. The GRIK2 (one of the kainate receptors) gene resides in a genetic linkage region (6q21) associated with bipolar disorder (BPD). The gene coding for GRIK2 has been suggested as a candidate gene for autism based on its localization in the autism-specific region on chromosome 6q21 and the involvement of receptor protein in cognitive functions like learning and memory. GRIK2 belongs to the gl...

重组蛋白

ALDH1A1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01583

Species: Human

Expression System: E. coli

ALDH1A2 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00710

Species: Human

Expression System: E. coli

ALDH1A3 Protein, Human, Recombinant (His)

Cat.No: TMPY-01899

Species: Human

Expression System: E. coli

ALDH1A3 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-06352

Species: Mouse

Expression System: E. coli

GRIK2 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-04318

Species: Human

Expression System: HEK293 Cells

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