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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T12926 |
SJB3-019A
|
Others; DUB | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Others; Ubiquitination |
SJB3-019A 是一种有效的、有效的和新型的泛素特异性蛋白酶1(USP1)抑制剂,在 K562细胞中促进 ID1降解和细胞毒性的作用是 SJB2-043的5倍,IC50为0.0781 μM。SJB3-019A 抑制细胞增殖,使细胞凋亡。 | |||
T71651 |
GSK1370319A
|
||
GSK1370319A is a potent P2X7 antagonist (IC50 = 3.2 nM). GSK1370319A inhibits ATP-induced increase in IL-1β release and caspase 1 activation in lipopolysaccharide (LPS)-primed mixed glia by blocking assembly of the inflammasome in a pannexin 1-dependent manner. GSK1370319A also inhibits ATP-induced subregion-specific neuronal loss in hippocampal organotypic slice cultures, which is dependent on its ability to prevent inflammasome assembly in glia. Significantly, GSK1370319A attenuates age-relate... | |||
T79021 | GSK3839919A | ||
GSK3839919A为高效HIV-1整合酶抑制剂。 | |||
T62796 | VEGFR-2-IN-13 | ||
VEGFR-2-IN-13 (Compound 19a) 是一种有效的 VEGFR-2 抑制剂 (IC50: 3.4 nM)。VEGFR-2-IN-13 能够将 HepG2 的细胞周期停滞在 G2/M 期,诱导细胞凋亡 (apoptosis)。 | |||
T83529 |
(Rac)-Luciferin 6′-methyl ether sodium
(Rac)-6′-Methoxyluciferin sodium |
||
D-Luciferin 6'-methyl ether (6'-Methoxyluciferin; compound 19a) sodium 是北美萤火虫Photinus pyralis荧光素酶 (PpyLuc) 的有效抑制剂,具有0.1 μM的IC50值。作为D-荧光素的类似物,本化合物在PpyLuc的ATP及荧光素结合位点展示了非特异性的相互作用。 | |||
T60632 |
Xanthine oxidase-IN-4
|
||
Xanthine oxidase-IN-4 (化合物 19a) 是一种具有口服活性的有效黄嘌呤氧化酶 (XO) 抑制剂,IC50值为0.039 μM,可用于高尿酸血症和痛风的研究。Xanthine oxidase-IN-4 在氧嗪酸钾诱导的高尿酸血症大鼠中表现出降尿酸能力。 | |||
T40100 |
D-Luciferin 6′-methyl ether
6′-Methoxyluciferin,D-Luciferin 6′-methyl ether |
||
D-Luciferin 6′-methyl ether (also known as 6′-Methoxyluciferin or compound 19a) is a highly effective inhibitor of luciferase obtained from the North American firefly Photinus pyralis (referred to as PpyLuc). It exhibits an IC50 value of 0.1 μM. This compound, which is an analog of D-luciferin, interacts non-specifically with the ATP and luciferin binding sites within the active site of PpyLuc. | |||
T73129 |
STAT6-IN-1
|
||
STAT6-IN-1(化合物19a)是一种针对STAT6的SH2结构域表现出较高亲和力(IC50=0.028 µM)的STAT6抑制剂。该化合物主要用于研究过敏性肺病、过敏性鼻炎、慢性阻塞性肺病或癌症。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN2664 |
19alpha-Hydroxyfern-7-ene
|
Others | Others |
19alpha-Hydroxyfern-7-ene 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN2664,CAS号为 70588-12-4。 | |||
TN2839 |
2alpha,19alpha-Dihydroxy-3-oxo-urs-12-en-28-oic acid
|
HIV Protease | Microbiology/Virology; Proteases/Proteasome |
2alpha,19alpha-Dihydroxy-3-oxo-urs-12-en-28-oic acid has anti-HIV activity. It shows an inhibitory effect on the activation of Epstein-Barr virus early antigen (EBV-EA) induced by 12-O-tetradecanoylphorbol-13-acetate (TPA) and causes a significant delay o | |||
TN1197 |
19α-Hydroxyasiatic acid
23-羟基委陵菜酸,19 alpha-Hydroxyasiatic acid |
Others | Others |
19 alpha-Hydroxyasiatic acid shows significant anticoagulant effect on the extrinsic pathway. | |||
T6116 |
Bleomycin Sulfate
Blenoxane,硫酸博来霉素,硫酸博莱霉素,NSC125066 |
DNA/RNA Synthesis; Antibiotic | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology |
Bleomycin Sulfate (Blenoxane) 是一种糖肽抗生素,一种 DNA 合成抑制剂。Bleomycin Sulfate 可以引起 DNA 链断裂而不引起 RNA 链断裂。Bleomycin Sulfate 具有抗肿瘤活性。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01483 |
SLAMF7 Protein, Human, Recombinant (His)
19A,SLAM7,SLAM family member 7,CS1,CRACC,CD319 |
Human | HEK293 Cells |
SLAMF7 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 23.8 kDa and the accession number is Q9NQ25-1. | |||
TMPH-00976 |
DDX19A Protein, Human, Recombinant (His & SUMO)
DDX19L,DDX19A,DDX19-like protein,DEAD box protein <... |
Human | E. coli |
DDX19A Protein, Human, Recombinant (His & SUMO) is expressed in E. coli. | |||
TMPK-01258 |
SLAMF7 Protein, Cynomolgus, Recombinant (His)
19A,CD319,SLAMF7,Novel Ly9,FOAP-12,CRACC,CS1,CD2 su... |
Cynomolgus | HEK293 Cells |
SLAMF7 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 23.55 kDa and the accession number is XP_005541294.2. | |||
TMPY-05547 |
SLAMF7 Protein, Human, Recombinant (hFc), Biotinylated
CS1,SLAM7,CD319,SLAM family member 7,CRACC,19A |
Human | HEK293 Cells |
SLAMF7 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.1 kDa and the accession number is Q9NQ25-5. | |||
TMPJ-00221 |
SLAMF7 Protein, Human, Recombinant (His & Avi), Biotinylated
Membrane Protein FOAP-12,Novel Ly9,CRACC,SLAMF7,SLAM Family ... |
Human | HEK293 Cells |
SLAMF7 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag. The predicted molecular weight is 35-55 KDa and the accession number is Q9NQ25. | |||
TMPJ-00222 |
SLAMF7 Protein, Human, Recombinant (mFc)
CD2 Subset 1,CRACC,CD319,CS1,Membrane Protein FOAP-12,SLAMF7... |
Human | HEK293 Cells |
SLAMF7 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 60-90 KDa and the accession number is Q9NQ25. | |||
TMPJ-01442 |
SLAMF7 Protein, Rhesus macaque, Recombinant (His)
CD2 Subset 1,CD2-Like Receptor-Activating Cytotoxic Cells,No... |
Rhesus | HEK293 Cells |
SLAMF7 Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 30-50 KDa and the accession number is F7HQ72. | |||
TMPY-01213 |
SLAMF7 Protein, Mouse, Recombinant (His)
CS1,4930560D03Rik,19A24,19A,CRACC,SLAM fam... |
Mouse | HEK293 Cells |
SLAMF7 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 23.7 kDa and the accession number is A0A0R4J2D8. | |||
TMPY-05387 |
SLAMF7 Protein, Human, Recombinant (hFc)
SLAM family member 7,19A,SLAM7,CS1,CD319,CRACC |
Human | HEK293 Cells |
SLAMF7 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.1 kDa and the accession number is Q9NQ25-5. | |||
TMPY-02946 |
TAFA2/FAM19A2 Protein, Human, Recombinant (hFc)
TAFA2,family with sequence similarity 19 (chemokine (C-C mot... |
Human | HEK293 Cells |
FAM19A2 belongs to the FAM19/TAFA family. FAM19/TAFA family members are chemokine-like proteins. The biological functions of TAFA family members remain to be determined, but there are a few tentative hypotheses. First, TAFAs may modulate immune responses in the CNS by functioning as brain specific chemokines, and may act with other chemokines to optimize the recruitment and activity of immune cells in the CNS. Second, TAFAs may represent a novel class of neurokines that act as regulators of immu... | |||
TMPY-04050 |
FAM19A4 Protein, Human, Recombinant (hFc)
TAFA4,TAFA-4,family with sequence similarity 19 (chemokine (... |
Human | HEK293 Cells |
FAM19A4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40.1 kDa and the accession number is Q96LR4. | |||
TMPH-02576 |
TAFA1/FAM19A1 Protein, Mouse, Recombinant (His & Myc)
|
Mouse | E. coli |
Regulatory factor which is ligand for CMKLR2 and is involved in the modulation of neural stem-cell proliferation and differentiation. | |||
TMPH-00956 |
Aromatase/CYP19A1 Protein, Human, Recombinant (His)
ARO1,CYP19A1,Estrogen synthase,Cytochrome P450 ... |
Human | E. coli |
Aromatase/CYP19A1 Protein, Human, Recombinant (His) is expressed in E. coli. | |||
TMPK-00365 |
Siglec-10 Protein, Human, Recombinant (R119A, His & Avi), Biotinylated
PRO940,MGC126774,SLG2,SIGLEC10 |
Human | HEK293 Cells |
Siglec-10 Protein, Human, Recombinant (R119A, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 62.64 kDa and the accession number is Q96LC7-1. | |||
TMPH-02016 |
SLC19A1 Protein, Human, Recombinant (His & Myc)
|
Human | E. coli |
SLC19A1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli. | |||
TMPK-00699 |
FAM19A5 Protein, Human, Recombinant (His)
Chemokine-like protein TAFA-5,UNQ5208,Tafa5,QLLK5208,Fam... |
Human | E. coli |
FAM19A5 is a secretory protein that is predominantly expressed in the brain. Although the FAM19A5 gene has been found to be associated with neurological and/or psychiatric diseases, only limited information is available on its function in the brain. FAM19A5 plays a role in nervous system development from an early stage and increases its expression in response to pathological conditions in subsets of neurons and OPCs of the brain. FAM19A5 Protein, Human, Recombinant (His) is expressed in E. coli ... | |||
TMPK-01125 |
FAM19A5 Protein, Mouse, Recombinant (His)
Fam19a5,QLLK5208,Tafa5,Chemokine-like protein TAFA-... |
Mouse | E. coli |
FAM19A5 is a secretory protein that is predominantly expressed in the brain. Although the FAM19A5 gene has been found to be associated with neurological and/or psychiatric diseases, only limited information is available on its function in the brain. FAM19A5 plays a role in nervous system development from an early stage and increases its expression in response to pathological conditions in subsets of neurons and OPCs of the brain. FAM19A5 Protein, Mouse, Recombinant (His) is expressed in E. coli ... |