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Search Results for " β-adrenoceptor "

32

抑制剂 & 化合物

2

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T20898	(R)-Propranolol hydrochloride Dexpropranolol hydrochloride,(R)-(+)-Propranolol,盐酸普奈洛尔	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	(R)-Propranolol hydrochloride (Dexpropranolol hydrochloride) 是一种抗肾上腺素受体拮抗剂，是一种普萘洛尔的活性较低的对映体。Dexpropranolol 是一种非选择性的β-adrenergic receptor 拮抗剂，对 β1AR 和 β2AR 具有高亲和力。
T22236	Alprenolol hydrochloride 阿普洛尔盐酸盐,盐酸阿普洛尔	5-HT Receptor	GPCR/G Protein; Neuroscience
	Alprenolol hydrochloride 是一种非选择性β受体阻滞剂，也是5-HT1A 受体拮抗剂。
T1239	Indacaterol maleate 马来酸茚达特罗,QAB149	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Indacaterol maleate (QAB149) 是一种超长效的 β-肾上腺素受体激动剂。
T30846	CGP-20712 UNII-SIO2UEZ19H,CGP 20712	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	CGP-20712 是一种具有选择性的 β 1-肾上腺素受体拮抗剂,IC50 为 0.7 nM。
T30027	Amosulalol	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Amosulalol 是一种 α 和 β 肾上腺素能受体拮抗剂。
T35326	Labetalone hydrochloride Labetalone hydrochloride,Benzoic amide	Others	Others
	Labetalone hydrochloride (Benzoic amide) 是 Labetalol 的一种杂质。Labetalol 是一种口服有效的肾上腺素能受体阻断药物，对 α 和 β 受体部位都有竞争性拮抗作用。
T10812	Cicloprolol hydrochloride	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Cicloprolol hydrochloride 是一种新型有效且具有选择性的 β1-肾上腺素能受体 (β 1-adrenoceptor) 拮抗剂，具有部分激动剂活性，可用于研究冠心病。
T5028	Landiolol hydrochloride ONO-1101 hydrochloride,盐酸兰地洛尔	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Landiolol hydrochloride (ONO-1101 hydrochloride) 是一种肾上腺素能受体拮抗剂，是一种 beta1 高选择性的超短作用β- 阻断剂(β1 /β2 选择性 = 255:1, 半衰期 4 分钟)。
T10364	Arbutamine GP 21213	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Arbutamine (GP 21213) 是一种新型非选择性β-肾上腺素受体激动剂，具有α-1-拟交感神经活性。Arbutamine 促进心脏应激，增加心率、心脏收缩力。Arbutamine 可用于研究心脏应激和冠状动脉疾病。
T8580	Bupranolol	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Bupranolol 是竞争性的、口服活性的、非选择性的β-adrenoceptor 拮抗剂，无固有的拟交感神经活性。
T1282	Carteolol hydrochloride Arteoptic,Abbott-43326,OPC-1085 hydrochloride,盐酸卡替洛尔,Carteolol HCl,Mikelan	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Carteolol hydrochloride (Abbott-43326) 是一种非选择性的β肾上腺素受体阻断剂。
T0324	Isoxsuprine hydrochloride Duvadilan,Isolait,盐酸异克舒令,盐酸苯氧丙酚胺	Adrenergic Receptor; iGluR	GPCR/G Protein; Membrane transporter/Ion channel; Neuroscience
	Isoxsuprine hydrochloride (Isolait) 是 β 肾上腺素受体激动剂和NMDA 受体拮抗剂，对子宫肌层和胎盘的 β 肾上腺素受体的Ki 值分别为 13.65 和 3.48 μM。
T10302	Amibegron hydrochloride SR 58611A	Others	Others
	Amibegron hydrochloride is a selective β3-adrenoceptor agonist (EC50: 3.5 nM for β-adrenoceptor in rat colon). It has anxiolytic and antidepressant activity.
T13465	(+)-Penbutolol (+)-Isopenbutolol,(R)-Penbutolol	Others	Others
	(+)-Penbutolol is an antagonist of β-adrenoceptor(IC50 of 0.74 μM). (+)-Penbutolol is an optical isomer of l-penbutolol with Na+ channel-blocking action.
T22699	Cyanopindolol hemifumarate	Others	Others
	5-HT1A/1B antagonist and β-adrenoceptor antagonist
T24448	MEN935 Adimolol hydrochloride hydrate,MEN-935,Men 935
	MEN935 is an antihypertensive agent. It is also a β-adrenoceptor blocker.
T68835	Mindodilol
	Mindodilol is a β-adrenoceptor blocker and vasodilator.
T23343	SDZ 21009	Others	Others
	β-adrenoceptor and 5-HT1A/1B receptor antagonist
T71931	Clencyclohexerol
	Clencyclohexerol is an analog of clenbuterol. β-Adrenoceptor agonists, including clenbuterol, modulate protein synthesis and degradation and have therapeutic potential in muscle wasting disorders. β-adrenoceptor agonists have deleterious cardiovascular side effects when used systemically and at high concentrations.
T13982	(±)-Befunolol	Others	Others
	(±)-Befunolol is a blocking agent of β-adrenoceptor.
T68930	Milveterol
	Milveterol is a long-acting β(2)-adrenoceptor agonist.
T61577	Sulfinalol
	Sulfinalol为口服活性β-肾上腺素受体(β-adrenoceptor)拮抗剂，具备直接血管扩张功能。
T70194	AM92016
	AM92016 is a specific blocker of the time dependent delayed rectifier potassium current. AM92016 does not show any β-adrenoceptor blocking activity.
T11608	Epanolol Visacor,ICI141292	Others	Others
	Epanolol is a potent β-adrenoceptor partial agonist with a greater affinity for β1- than β2-adrenoceptors.
T61138	Bevantolol
	Bevantolol, a selective β-1 adrenoceptor antagonist, is utilized for the investigation of angina pectoris and hypertension [1].
T11786	KUL-7211 racemate KUL 7211 racemate	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	KUL 7211 is a selective β-adrenoceptor agonist. KUL 7211 racemate is the racemate of KUL 7211.
T21411	Isoproterenol Norisodrine,Isoprenaline,Novodrin,Isuprel,Medihaler-Iso	Endogenous Metabolite; Adrenergic Receptor	GPCR/G Protein; Metabolism; Neuroscience
	Isoproterenol (Norisodrine) 是一种非选择性且具有口服活性的 β-肾上腺素受体激动剂。Isoproterenol 是有效的外周血管扩张剂和支气管扩张剂。Isoproterenol 可用于研究心动过缓和支气管哮喘，用于治疗心脏传导阻滞、心动过缓。
T61918	Ro 363 hydrochloride
	Ro 363 hydrochloride 是一种有效的，高度选择性的 β1 肾上腺素受体 (β1-adrenoceptor) 激动剂。Ro 363 hydrochloride 是有效的正性肌力活化剂。Ro 363 hydrochloride 是心血管调节剂，可降低舒张压，显著增加心肌收缩力。
T5450	DL-071-IT Afurolol Hydrochloride,DL 071 IT	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	DL-071-IT (Afurolol Hydrochloride) 是一种有效的非选择性β-肾上腺素受体拮抗剂。 DL-071-IT 表现出内在的拟交感神经活性和弱的膜稳定活性。
T63356	Bopindolol fumarate
	Bopindolol ((±)-Bopindolol) fumarate 是一种具有部分激动剂活性的、口服具有活力的 β-肾上腺素受体 (ARs) 拮抗剂，对 β1- 和 β2-ARs 无选择性，对 β3-AR 亚型亲和力低。Bopindolol fumarate 是 Pindolol 的前体药物，能够用于研究原发性和肾血管性高血压。
T12550	Propranolol-d7 hydrochloride Propranolol D7 hydrochloride	Others	Others
	Propranolol D7 hydrochloride is a deuterium labeled Propranolol hydrochloride. Propranolol hydrochloride is a nonselective antagonist of β-adrenergic receptor (βAR).
T22872	Isamoltane hemifumarate	Others	Others
	5-HT1B antagonist

化合物

(R)-Propranolol hydrochloride

Cat.No: T20898

Synonym: Dexpropranolol hydrochloride,(R)-(+)-Propranolol,盐酸普奈洛尔

Target: Adrenergic Receptor

Alprenolol hydrochloride

Cat.No: T22236

Synonym: 阿普洛尔盐酸盐,盐酸阿普洛尔

Target: 5-HT Receptor

Indacaterol maleate

Cat.No: T1239

Synonym: 马来酸茚达特罗,QAB149

Target: Adrenergic Receptor

Cat.No: T30846

Synonym: UNII-SIO2UEZ19H,CGP 20712

Target: Adrenergic Receptor

Cat.No: T30027

Target: Adrenergic Receptor

Labetalone hydrochloride

Cat.No: T35326

Synonym: Labetalone hydrochloride,Benzoic amide

Target: Others

Cicloprolol hydrochloride

Cat.No: T10812

Target: Adrenergic Receptor

Landiolol hydrochloride

Cat.No: T5028

Synonym: ONO-1101 hydrochloride,盐酸兰地洛尔

Target: Adrenergic Receptor

Cat.No: T10364

Synonym: GP 21213

Target: Adrenergic Receptor

Cat.No: T8580

Target: Adrenergic Receptor

Carteolol hydrochloride

Cat.No: T1282

Synonym: Arteoptic,Abbott-43326,OPC-1085 hydrochloride,盐酸卡替洛尔,Carteolol HCl,Mikelan

Target: Adrenergic Receptor

Isoxsuprine hydrochloride

Cat.No: T0324

Synonym: Duvadilan,Isolait,盐酸异克舒令,盐酸苯氧丙酚胺

Target: Adrenergic Receptor, iGluR

Amibegron hydrochloride

Cat.No: T10302

Synonym: SR 58611A

Target: Others

Cat.No: T13465

Synonym: (+)-Isopenbutolol,(R)-Penbutolol

Target: Others

Cyanopindolol hemifumarate

Cat.No: T22699

Target: Others

Cat.No: T24448

Synonym: Adimolol hydrochloride hydrate,MEN-935,Men 935

Cat.No: T68835

Cat.No: T23343

Target: Others

Clencyclohexerol

Cat.No: T71931

Cat.No: T13982

Target: Others

Cat.No: T68930

Cat.No: T61577

Cat.No: T70194

Cat.No: T11608

Synonym: Visacor,ICI141292

Target: Others

Cat.No: T61138

KUL-7211 racemate

Cat.No: T11786

Synonym: KUL 7211 racemate

Target: Adrenergic Receptor

Cat.No: T21411

Synonym: Norisodrine,Isoprenaline,Novodrin,Isuprel,Medihaler-Iso

Target: Endogenous Metabolite, Adrenergic Receptor

Ro 363 hydrochloride

Cat.No: T61918

Cat.No: T5450

Synonym: Afurolol Hydrochloride,DL 071 IT

Target: Adrenergic Receptor

Bopindolol fumarate

Cat.No: T63356

Propranolol-d7 hydrochloride

Cat.No: T12550

Synonym: Propranolol D7 hydrochloride

Target: Others

Isamoltane hemifumarate

Cat.No: T22872

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T3158	Harmane Loturine,Harman,Aribine,哈尔满碱	Adrenergic Receptor; Monoamine Oxidase; Imidazoline Receptor	GPCR/G Protein; Neuroscience
	Harmane (Loturine) 是一种在咖啡和烟草烟雾中发现的 β-咔啉生物碱，是有效的神经毒素，可引起严重的动作震颤和精神病学表现。它还是选择性的单胺氧化酶抑制剂，具有致突变作用，对 MAO A/B 的 IC50值分别为 0.5 和 5 μM。
T2889	Isoferulic acid Isoferulate,Hesperetic acid,3-Hydroxy-4-methoxycinnamic acid,Hesperetate,异阿魏酸	Influenza Virus; Adrenergic Receptor	GPCR/G Protein; Microbiology/Virology; Neuroscience
	Isoferulic acid (Hesperetate) 是一种肉桂酸衍生物，有抗糖尿病活性和抗流感病毒活性。它能结合并激活 α1-肾上腺素能受体，增强 β-内啡肽的分泌并增加体外葡萄糖的使用。

天然产物

Cat.No: T3158

Synonym: Loturine,Harman,Aribine,哈尔满碱

Target: Adrenergic Receptor, Monoamine Oxidase, Imidazoline Receptor

Isoferulic acid

Cat.No: T2889

Synonym: Isoferulate,Hesperetic acid,3-Hydroxy-4-methoxycinnamic acid,Hesperetate,异阿魏酸

Target: Influenza Virus, Adrenergic Receptor

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