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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T15116 | Dichlorophenyl-ABA | Others | Others |
Dichlorophenyl-ABA is a transthyretin (TTR) amyloid fibril formation inhibitor. It inhibits aggregate formation in more than 80% in TTR L55P-expressing cells. | |||
T83243 |
7'-Hydroxy ABA
7'-OH ABA |
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7'-Hydroxy ABA (7'-OH ABA) 是由 Abscisic acid (Abscisic acid) 通过羟基化其7'-碳原子形成的代谢产物,具备显著的激素活性。 | |||
T24695 |
Quinabactin
LC-66C6,ABA mimics 1,AM1,LC66C6,LC 66C6 |
Others | Others |
Quinabactin (LC-66C6) 是一种有效的磺酰胺脱落酸 ABA 激动剂。Quinabactin 促进成年拟南芥和大豆植物的保卫细胞关闭、抑制水分流失,抑制种子萌发,提高耐旱性。 | |||
T6329 |
3-Aminobenzamide
3-AB,INO1001,INO-1001,3-ABA,PARP-IN-1,INO 1001 |
PARP | Chromatin/Epigenetic; DNA Damage/DNA Repair |
3-Aminobenzamide (PARP-IN-1) 是一种有效的 PARP 抑制剂,在 CHO 细胞中,对 PARP 的 IC50值约为 50 nM。它是再灌注过程中氧化剂诱导的肌细胞功能障碍的介质。 | |||
T74995 | 8′-Hydroxy ABA | ||
8′-Hydroxy ABA (8'-OH-ABA) 为脱落酸 (ABA) 的主要分解产物,该化合物具备激素活性,能促进油合成。然而,8′-Hydroxy ABA 是一种不稳定的化合物。 | |||
T5952 |
Diniconazole
烯唑醇,Rac-diniconazole |
Antibacterial | Microbiology/Virology |
Diniconazole (Rac-diniconazole) 是新型杀菌剂, 抑制由酵母细胞色素P-450催化的羊毛甾醇14α-脱甲基化。 | |||
T60952 |
Fluridone
EL-171 |
Others | Others |
Fluridone (EL-171) 是 一种有效的合成脱落酸 (ABA) 的抑制剂,抑制 AchnFAR 和 TF 基因的表达,减少伯醇的形成。Fluridone 常作为水生除草剂用于控制入侵植物,也被用来控制水螅和欧亚水螅等物种。 | |||
T21482 |
Uniconazole
|
P450; ROS Kinase | Metabolism; Tyrosine Kinase/Adaptors |
Uniconazole 是植物生长调节剂,能够抑制细胞色素 P450 707As (Ki=68 nM)。他是分解脱落酸的酶家族成员,能够抑制赤霉素和甾醇的生物合成。 | |||
T23756 |
AS6
AS 6,AS-6 |
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AS6 is an ABA-induced PYL-PP2C interaction antagonist in a dose-dependent manner. | |||
T68792 |
Abamine
|
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Abamine is an inhibitor of 9-Cis-Epoxycarotenoid dioxygenase (NCED), the key regulatory enzyme in the plant hormone abscisic acid (ABA) biosynthesis pathway. | |||
T69869 |
Cyanabactin
|
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Cyanabactin is a novel ABA receptor agonist. It preferentially activates Pyrabactin Resistance 1 (PYR1) with low nanomolar potency. | |||
T38225 |
N-Arachidonoyl-3-hydroxy-γ-Aminobutyric Acid
|
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Several different arachidonoyl amino acids, including N-arachidonoyl-3-hydroxy-γ-aminobutyric acid (NAG-3H-ABA), have been isolated and characterized from bovine brain. The glycine congener was further characterized and found to suppress formalin-induced pain in rats. NAG-3H-ABA was also found in rat brain by LC-MS techniques, but has not been fully characterized to date. Most arachidonoyl amino acids are poor ligands for the CB1 receptor. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN1066 |
Filixic acid ABA
|
Influenza Virus | Microbiology/Virology |
Filixic acid ABA exhibits inhibitory effects on neuraminidase of influenza virus H5N1 with IC50 as 29.57 ± 2.48 μM, it may have anti-influenza virus activity. | |||
T6368 |
Abscisic Acid
Abscisin II,Dormin,(+)-脱落酸,(+)-ABA,Abscisic Acid (Dormin) |
Others; Proton pump; Endogenous Metabolite | Membrane transporter/Ion channel; Metabolism; Others |
Abscisic Acid (Dormin) 是具有口服活性的植物激素,存在于蔬菜和水果中,也是内源性的哺乳动物激素。它是生长抑制剂,可以调节植物生长发育。他抑制质子泵,并导致 Ca2+依赖性的质膜去极化。它是 LANCL2 的天然配体,属于胰岛素敏感化合物,在糖尿病前期,2 型糖尿病和代谢综合征的研究中具有价值。 | |||
T3014 |
(±)-Abscisic acid
Abscisic acid,Dormin,脱落酸,Abscisinsaeure |
Others | Others |
(±)-Abscisic acid (Dormin) 是一种口服具有活性的植物激素,也存在与动物中。它可以调节哺乳动物的血糖。 | |||
T83580 |
(±)-trans-Abscisic acid
(±)-trans-ABA |
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(±)-trans-Abscisic acid ((±)-trans-ABA) 为一种可以从草莓树 (Arbutus unedo L.) 蜂蜜中分离提取的酸性化合物。 | |||
T39605 |
β-D-Glucopyranosyl abscisate
ABA-GE,β-D-Glucopyranosyl abscisate,(S)-cis,trans-Abscisicacidglucosylester |
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β-D-Glucopyranosyl abscisate (ABA-GE) is a hydrolyzable conjugate of abscisic acid (ABA), which predominantly accumulates in the vacuole and likely in the endoplasmic reticulum. The deconjugation of β-D-Glucopyranosyl abscisate enables a swift release of free ABA in response to abiotic stress factors like dehydration and salt stress. β-D-Glucopyranosyl abscisate plays a crucial role in maintaining ABA homeostasis. | |||
TN5250 |
Vomifoliol
|
VEGFR; NF-κB; HIF | Angiogenesis; Chromatin/Epigenetic; NF-κB; Tyrosine Kinase/Adaptors |
Vomifoliol is most likely the immediate precursor of dehydrovomifoliol, because of the organism converted abscisic acid (ABA), to dehydrovomifoliol as the major metabolise, and a cell-free extract exhibits vomifoliol dehydrogenase activity. Vomifoliol and |