纤维生长因子受体 (Fibroblast Growth Factor Receptors, FGFRs) 是与纤维生长因子 (Fibroblast Growth Factor ,FGF) 蛋白家族成员结合的受体。FGFR 由一个由三个免疫球蛋白样结构域组成的细胞外配体结构域、一个跨膜螺旋结构域和一个具有酪氨酸激酶活性的细胞内结构域组成。FGF/FGFR信号通路与多种癌症有关。目前有作用于所有 FGFR1-4 和其他蛋白质的非选择性 FGFR 抑制剂,以及作用于部分/全部 FGFR1-4 的一些选择性 FGFR 抑制剂,例如AZD4547、BGJ398、JNJ42756493和PD173074。
Cat. No. | Product Name / Synonyms | Species | Expression System |
---|---|---|---|
TMPY-06037 | FGFR4 Protein, Human, Recombinant (His), Biotinylated
FGFR4 Protein, Human, Recombinant (His), Biotinylated
|
Human | HEK293 Cells |
FGFR4 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the acces... | |||
TMPY-06321 | FGFR2 Protein, Human, Recombinant (alpha(IIIb), His & Avi), Biotinylated
FGFR2 Protein, Human, Recombinant (alpha(IIIb), His & Avi), Biotinylated
|
Human | HEK293 Cells |
FGFR2 Protein, Human, Recombinant (alpha(IIIb), His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular wei... | |||
TMPY-04165 | FGFR3 Protein, Human, Recombinant (His)
FGFR3 Protein, Human, Recombinant (His)
|
Human | HEK293 Cells |
FGFR3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.6 kDa and the accession number ... | |||
TMPY-00341 | FGFR3 Protein, Human, Recombinant (alpha IIIb, His)
FGFR3 Protein, Human, Recombinant (alpha IIIb, His)
|
Human | HEK293 Cells |
FGFR3 Protein, Human, Recombinant (alpha IIIb, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accessi... | |||
TMPY-06036 | FGFR1 Protein, Human, Recombinant (alpha (IIIb), His)
FGFR1 Protein, Human, Recombinant (alpha (IIIb), His)
|
Human | HEK293 Cells |
FGFR1 Protein, Human, Recombinant (alpha (IIIb), His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.5 kDa and the acc... | |||
TMPY-06034 | FGFR1 Protein, Human, Recombinant (beta (IIIb), His)
FGFR1 Protein, Human, Recombinant (beta (IIIb), His)
|
Human | HEK293 Cells |
FGFR1 Protein, Human, Recombinant (beta (IIIb), His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.8 kDa and the acce... | |||
TMPY-02112 | FGFR4 Protein, Human, Recombinant (His)
FGFR4 Protein, Human, Recombinant (His)
|
Human | HEK293 Cells |
FGFR4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is... | |||
TMPY-01011 | FGFR1 Protein, Human, Recombinant (His)
FGFR1 Protein, Human, Recombinant (His)
|
Human | HEK293 Cells |
FGFR1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31 kDa and the accession number is... | |||
TMPY-00423 | FGFR2 Protein, Human, Recombinant (alpha IIIb, hFc)
FGFR2 Protein, Human, Recombinant (alpha IIIb, hFc)
|
Human | HEK293 Cells |
FGFR2 Protein, Human, Recombinant (alpha IIIb, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 66.3 kDa and the acces... | |||
TMPY-00972 | FGFR2 Protein, Human, Recombinant (His & hFc)
FGFR2 Protein, Human, Recombinant (His & hFc)
|
Human | HEK293 Cells |
FGFR2 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 67.6 kDa and the acc... | |||
TMPY-03357 | FGFR2 Protein, Mouse, Recombinant (hFc)
FGFR2 Protein, Mouse, Recombinant (hFc)
|
Mouse | HEK293 Cells |
FGFR2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 54.1 kDa and the accession number ... |