纤维生长因子受体 (Fibroblast Growth Factor Receptors, FGFRs) 是与纤维生长因子 (Fibroblast Growth Factor ,FGF) 蛋白家族成员结合的受体。FGFR 由一个由三个免疫球蛋白样结构域组成的细胞外配体结构域、一个跨膜螺旋结构域和一个具有酪氨酸激酶活性的细胞内结构域组成。FGF/FGFR信号通路与多种癌症有关。目前有作用于所有 FGFR1-4 和其他蛋白质的非选择性 FGFR 抑制剂,以及作用于部分/全部 FGFR1-4 的一些选择性 FGFR 抑制剂,例如AZD4547、BGJ398、JNJ42756493和PD173074。
Cat. No. | Product Name / Synonyms | Species | Expression System |
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TMPK-00395 | FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | HEK293 Cells |
FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weigh... | |||
TMPK-00396 | FGFR2 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
FGFR2 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | HEK293 Cells |
FGFR2 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weigh... | |||
TMPK-00397 | FGFR2 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
FGFR2 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | HEK293 Cells |
FGFR2 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight... | |||
TMPK-00398 | FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi)
FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi)
|
Human | HEK293 Cells |
FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi) is expressed in HEK293 mammalian cells with C-Avi tag. The predicted molecular weight is 15.49 kDa and... | |||
TMPK-00399 | FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi), Biotinylated
FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi), Biotinylated
|
Human | HEK293 Cells |
FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Avi tag. The predicted molecular weight is... | |||
TMPK-00400 | FGFR2 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
FGFR2 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | HEK293 Cells |
FGFR2 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight... | |||
TMPK-00401 | FGFR2 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
FGFR2 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | HEK293 Cells |
Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, t... | |||
TMPK-00475 | FGFR2 beta (IIIb) Protein, Cynomolgus, Recombinant (His)
FGFR2 beta (IIIb) Protein, Cynomolgus, Recombinant (His)
|
Cynomolgus | HEK293 Cells |
FGFR2 beta (IIIb) Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 26.2 kDa and th... | |||
TMPK-00686 | FGFR3 alpha (IIIb) Protein, Mouse, Recombinant (His)
FGFR3 alpha (IIIb) Protein, Mouse, Recombinant (His)
|
Mouse | HEK293 Cells |
FGFR3 alpha (IIIb) Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 37.09 kDa and the a... | |||
TMPK-00847 | FGFR2 beta (IIIb) Protein, Mouse, Recombinant (His)
FGFR2 beta (IIIb) Protein, Mouse, Recombinant (His)
|
Mouse | HEK293 Cells |
FGFR2 beta (IIIb) Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 26.3 kDa and the acc... | |||
TMPK-01322 | FGFR4 Protein, Rhesus macaque, Recombinant (His)
FGFR4 Protein, Rhesus macaque, Recombinant (His)
|
Rhesus | HEK293 Cells |
FGFR4 Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 39.66 kDa and the acces... | |||
TMPY-00257 | FGFR3 Protein, Cynomolgus, Rhesus, Recombinant (His)
FGFR3 Protein, Cynomolgus, Rhesus, Recombinant (His)
|
Cynomolgus,Rhesus | HEK293 Cells |
FGFR3 Protein, Cynomolgus, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.5 kDa and the acce... | |||
TMPY-00351 | FGFR2 Protein, Human, Recombinant (beta IIIc, His)
FGFR2 Protein, Human, Recombinant (beta IIIc, His)
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Human | HEK293 Cells |
FGFR2 Protein, Human, Recombinant (beta IIIc, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.2 kDa and the access... | |||
TMPY-00389 | FGFR3 Protein, Human, Recombinant (alpha IIIb, hFc)
FGFR3 Protein, Human, Recombinant (alpha IIIb, hFc)
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Human | HEK293 Cells |
FGFR3 Protein, Human, Recombinant (alpha IIIb, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65.3 kDa and the acces... | |||
TMPY-00806 | FGFR4 Protein, Human, Recombinant (hFc)
FGFR4 Protein, Human, Recombinant (hFc)
|
Human | HEK293 Cells |
FGFR4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 66 kDa and the accession number is... | |||
TMPY-00973 | FGFR3 Protein, Mouse, Recombinant (His & hFc)
FGFR3 Protein, Mouse, Recombinant (His & hFc)
|
Mouse | HEK293 Cells |
FGFR3 Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 66 kDa and the acces... | |||
TMPY-00974 | FGFR4 Protein, Mouse, Recombinant (His)
FGFR4 Protein, Mouse, Recombinant (His)
|
Mouse | HEK293 Cells |
FGFR4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is... | |||
TMPY-01019 | FGFR4 Protein, Mouse, Recombinant (His & hFc)
FGFR4 Protein, Mouse, Recombinant (His & hFc)
|
Mouse | HEK293 Cells |
FGFR4 Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 67 kDa and the acces... | |||
TMPY-01208 | FGFR3 Protein, Mouse, Recombinant (His)
FGFR3 Protein, Mouse, Recombinant (His)
|
Mouse | HEK293 Cells |
FGFR3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37 kDa and the accession number is... | |||
TMPY-01228 | FGFR2 Protein, Human, Recombinant (aa 1-377, His)
FGFR2 Protein, Human, Recombinant (aa 1-377, His)
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Human | HEK293 Cells |
FGFR2 Protein, Human, Recombinant (aa 1-377, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 41 kDa and the accession... |