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12

抑制剂 & 化合物

2

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T6488	Epinastine hydrochloride Alesion,Epinastine HCl,WAL-801CL HCl,依匹斯汀盐酸盐,Elestat	5-HT Receptor; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Epinastine hydrochloride (WAL-801CL HCl) 是抗组胺剂和肥大细胞稳定剂，是一种可口服的选择性组胺 H1 受体拮抗剂，可抑制 IL-8 释放，具有抗过敏作用。
TP2500	Cholecystokinin (26-33) free acid CCK (26-33) free acid	cholecystokinin	GPCR/G Protein
	Cholecystokinin (26-33) free acid 是胆囊收缩素 (CCK) 的一部分，是脊椎动物中枢神经系统中存在的 CCKB 型受体的高选择性配体，可诱导大鼠轻度味觉厌恶条件反射。
T10046	16,16-Dimethyl prostaglandin E2 16,16-dimethyl PGE2	Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation
	16,16-Dimethyl prostaglandin E2 is an orally active vertebrate Hematopoietic stem cells homeostasis critical regulator. It can act through EP2/EP4 and has an interaction with the Wnt pathway.
TP1352	[Arg8]-Vasotocin TFA (113-80-4 free base) [Arg8]-Vasotocin TFA
	[Arg8]-Vasotocin (TFA) is a nonmammalian vertebrate neurohypophyseal peptide.
T80719	Z-PDLDA-NHOH
	Z-PDLDA-NHOH是高效且具有特异性的脊椎动物胶原酶抑制剂。
T81919	Locustatachykinin II Lom-TK II
	Locustachykinin II (Lom-TK II)为具有同源性的昆虫神经肽，与脊椎动物的tachykinin肽家族相似。此化合物适用于研究昆虫的内分泌系统。
T75993	Pepsin A
	Pepsin A 是人和猪胃中的主要蛋白酶，是一种类似胃蛋白酶的胃小蛋白水解酶。Pepsin A 有助于脊椎动物胃中食物蛋白质的蛋白质水解。
T71207	(R)-(+)-Blebbistatin O-Benzoate
	(R)-(+)-Blebbistatin O-Benzoate is a derivative of Blebbistatin. (R)-(+)-Blebbistatin is a 1-phenyl-2-pyrrolidinone derivative and a selective inhibitor of non-muscle myosin II. It blocks cell blebbing rapidly and reversibly and also disrupts directed cell migration and cytokinesis in vertebrate cell. (R)-(+)-Blebbistatin can also inhibit contraction of the cleavage furrow without disrupting mitosis or contractile ring assembly. (R)-(+)-Blebbistatin is suitable as a negative control for (S)-(-)-...
T80423	Phoenixin-20 PNX-20	Epigenetic Reader Domain	Chromatin/Epigenetic
	Phoenixin-20（PNX-20）为脊椎动物内具激素样生物活性肽，能激活下丘脑-垂体-性腺轴，调控哺乳类生殖过程。该肽通过CREB-PGC-1α途径增进神经元线粒体生物发生。
T74914	ODN D-SL01
	ODN D-SL01，一种B类CpG ODN（寡脱氧核苷酸），作为TLR9激动剂，显示出显著的免疫刺激活性，并对多种脊椎动物物种表现出抗癌效应。序列为5'-T-C-G-C-G-A-C-G-T-T-C-G-C-C-C-G-A-C-G-T-T-C-G-G-T-A-3'。
T36335	(S)-nitro-Blebbistatin
	(S)-nitro-Blebbistatin is a more stable form of (-)-blebbistatin , which is a selective cell-permeable inhibitor of non-muscle myosin II ATPases. (-)-Blebbistatin rapidly and reversibly inhibits Mg-ATPase activity and in vitro motility of non-muscle myosin IIA and IIB for several species (IC50s = 0.5-5 μM), while poorly inhibiting smooth muscle myosin (IC50 = 80 μM). Through these effects, it blocks apoptosis-related bleb formation, directed cell migration, and cytokinesis in vertebrate cells. H...
T36400	para-amino-Blebbistatin
	para-amino-Blebbistatin is a more water-soluble form of (S)-4'-nitro-blebbistatin , which is a more stable and less phototoxic form of (-)-blebbistatin .1,2,3 (-)-Blebbistatin is a selective cell-permeable inhibitor of non-muscle myosin II ATPases that rapidly and reversibly inhibits Mg-ATPase activity and in vitro motility of non-muscle myosin IIA and IIB for several species (IC50s = 0.5-5 μM), while poorly inhibiting smooth muscle myosin (IC50 = 80 μM).2,3,4 Through these effects, it blocks ap...

化合物

Epinastine hydrochloride

Cat.No: T6488

Synonym: Alesion,Epinastine HCl,WAL-801CL HCl,依匹斯汀盐酸盐,Elestat

Target: 5-HT Receptor, Histamine Receptor

Cholecystokinin (26-33) free acid

Cat.No: TP2500

Synonym: CCK (26-33) free acid

Target: cholecystokinin

16,16-Dimethyl prostaglandin E2

Cat.No: T10046

Synonym: 16,16-dimethyl PGE2

Target: Prostaglandin Receptor

[Arg8]-Vasotocin TFA (113-80-4 free base)

Cat.No: TP1352

Synonym: [Arg8]-Vasotocin TFA

Cat.No: T80719

Locustatachykinin II

Cat.No: T81919

Synonym: Lom-TK II

Cat.No: T75993

(R)-(+)-Blebbistatin O-Benzoate

Cat.No: T71207

Cat.No: T80423

Synonym: PNX-20

Target: Epigenetic Reader Domain

Cat.No: T74914

(S)-nitro-Blebbistatin

Cat.No: T36335

para-amino-Blebbistatin

Cat.No: T36400

Cat. No.	Product Name	Target	Signaling Pathways
T4888	Phosphocreatine disodium hydrate 磷酸肌酸二钠盐,Phosphocreatine disodium salt hydrate	Others; Endogenous Metabolite	Metabolism; Others
	Phosphocreatine disodium hydrate 是内源性代谢产物的一种。
T4883	Creatine Methylguanidoacetic acid,肌酸	Endogenous Metabolite	Metabolism
	Creatine (Methylguanidoacetic acid) 是一种内源性氨基酸代谢物，在细胞能量中发挥重要作用，尤其是在肌肉和大脑中。

天然产物

Phosphocreatine disodium hydrate

Cat.No: T4888

Synonym: 磷酸肌酸二钠盐,Phosphocreatine disodium salt hydrate

Target: Others, Endogenous Metabolite

Cat.No: T4883

Synonym: Methylguanidoacetic acid,肌酸

Target: Endogenous Metabolite

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