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Search Results for " tropine "

22

抑制剂 & 化合物

4

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T124776	Tropine isobutyrate
	Tropine isobutyrate 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T124776。
T125833	Tropine nonanoate
	Tropine nonanoate 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T125833。
T14345	Atropine methyl bromide 甲溴阿托品,Methylatropine bromide	AChR	Neuroscience
	Atropine methyl bromide (Methylatropine bromide) is a quaternary ammonium salt of atropine, characterized as a muscarinic receptor (mAChR) antagonist. It functions as a mydriatic to dilate the pupil during ophthalmic examination. Compared to atropine, it demonstrates reduced penetration into the central nervous system[1][2]. Its high polarity makes it particularly effective in relieving pyloric spasm in infants.
T1336	Benztropine mesylate Benzotropine mesylate,苯扎托品,Benzatropine mesylate,Benztropine methanesulfonate,甲磺酸苯扎托品	Dopamine Receptor; AChR; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Benztropine mesylate (Benztropine methanesulfonate) 是一种可口服的中枢性抗胆碱能剂，用于帕金森氏病的研究。它是抗组胺剂，抑制多巴胺的吸收。它也是人 D2多巴胺受体的变构拮抗剂，具有抗癌症干细胞的作用。
T0427	Homatropine Methylbromide Homatropine methobromide,溴甲基后马托品	AChR	Neuroscience
	Homatropine Methylbromide 是一种毒蕈碱受体 AChR 拮抗剂，抑制 WKY-E 和 SHR-E ，IC50分别为 162.5 和 170.3 nM。
T4981	Anisotropine Methylbromide	Prostaglandin Receptor; AChR	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Anisotropine Methylbromide 是一种抗胆碱能药物，已用于缓解胃肠道痉挛和抑制胃酸分泌。
T21673	N-Isopropylnoratropine	Others	Others
	N-Isopropylnoratropine 是一种去甲托品衍生物，是生产异丙托溴铵(ipratropium) 的中间体，异丙托溴铵是一种通过抗胆碱能途径产生的阿托品样支气管扩张药。它用于检查异丙托溴铵的稳定性。
T1341L	Nortropine Hydrochloride
	Nortropine Hydrochloride is a secondary metabolite of tropine derivative drugs.
T69549	Ethybenztropine HCl
	Ethybenztropine HCl is an anticholinergic which is used as an antiparkinsonian agent. Ethybenztropine may also act as a dopamine reuptake inhibitor.
T71631	Eucatropine
	Eucatropine，作为一种有效的毒蕈碱型乙酰胆碱受体(mAChR)抑制剂，具有0.583 μM的IC50值，归类为抗胆碱能剂。
T69849	Deptropine citrate
	Deptropine citrate is a well-known H1-histamine receptor antagonist and muscarinic receptor antagonist. It is prescribed frequently for treatment of asthma. Recently deptropine has garnered interest as a potential treatment for breast cancer. In vitro studies have shown deptropine citrate has inhibitory effects on cell viability and mammosphere formation in Breast Cancer Stem Cells (BCSCs). However, it does not seem to inhibit the self-renewal capacity of the breast cancer cell line MDA-MB-231 w...
T23763	Atropine Oxide NSC 72861,NSC72861,NSC-72861
	Atropine Oxide is a derivative of Atropine. Atropine is a competitive antagonist of the muscarinic acetylcholine receptor types M1, M2, M3, M4, and M5. Atropine is a medication to treat certain types of nerve agents and pesticide poisonings as well as som
T80637	Homatropine hydrochloride
	Homatropine hydrochloride为口服抗胆碱能剂，迅速扩张瞳孔并导致睫状肌麻痹。该化合物也展现出镇咳效果，适用于眼科疾病和止咳研究。
T27295	Ethybenztropine Etibenzatropina,Ethylbenatropine,Etybenzatropine,Ethylbenztropine
	Ethybenztropine is an anticholinergic used as an antiparkinsonian agent and may also act as a dopamine reuptake inhibitor.
T124775	Valtropine
	Valtropine 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T124775。
T30206	Atropine hydrobromide
	Atropine hydrobromide is a biochemical.
T23781	Benzatropine Akitan,Benztropine,NK 02,Cogentinol,Cogentine
	Benzatropine is a centrally active muscarinic antagonist. It also inhibits the uptake of dopamine. It has been used in the symptomatic treatment of Parkinson's Disease.
T30207	Atropine iodomethylate
	Atropine iodomethylate is a biochemical.
T33640	Neotropine W290,W 290,W-290
	Neotropine is a biochemical.
T69232	Atropine Oxide Hydrochloride
	Atropine Oxide is a derivative of Atropine. Atropine is a medication to treat certain types of nerve agent and pesticide poisonings as well as some types of slow heart rate and to decrease saliva production during surgery. Atropine is a competitive antagonist of the muscarinic acetylcholine receptor types M1, M2, M3, M4 and M5. It is classified as an anticholinergic drug (parasympatholytic).
T69614	Ethybenztropine HBr
	Ethybenztropine HBr is an anticholinergic which is used as an antiparkinsonian agent. Ethybenztropine may also act as a dopamine reuptake inhibitor.
T36204	Methylatropine (nitrate)
	Methylatropine is an antagonist of muscarinic acetylcholine receptors (IC50= <0.1 nM in a radioligand binding assay using isolated porcine brain membranes) and a derivative of atropine .1,2It reduces acetylcholine-induced decreases in blood pressure in rats when administered intravenously with an ED50value of 5.5 μg/kg.2Methylatropine reduces salivation, induces mydriasis, and increases heart rate in dogs.3 1.Schmeller, T., Sporer, F., Sauerwein, M., et al.Binding of tropane alkaloids to nicotin...

化合物

Tropine isobutyrate

Cat.No: T124776

Tropine nonanoate

Cat.No: T125833

Atropine methyl bromide

Cat.No: T14345

Synonym: 甲溴阿托品,Methylatropine bromide

Target: AChR

Benztropine mesylate

Cat.No: T1336

Synonym: Benzotropine mesylate,苯扎托品,Benzatropine mesylate,Benztropine methanesulfonate,甲磺酸苯扎托品

Target: Dopamine Receptor, AChR, Histamine Receptor

Homatropine Methylbromide

Cat.No: T0427

Synonym: Homatropine methobromide,溴甲基后马托品

Target: AChR

Anisotropine Methylbromide

Cat.No: T4981

Target: Prostaglandin Receptor, AChR

N-Isopropylnoratropine

Cat.No: T21673

Target: Others

Nortropine Hydrochloride

Cat.No: T1341L

Ethybenztropine HCl

Cat.No: T69549

Cat.No: T71631

Deptropine citrate

Cat.No: T69849

Cat.No: T23763

Synonym: NSC 72861,NSC72861,NSC-72861

Homatropine hydrochloride

Cat.No: T80637

Ethybenztropine

Cat.No: T27295

Synonym: Etibenzatropina,Ethylbenatropine,Etybenzatropine,Ethylbenztropine

Cat.No: T124775

Atropine hydrobromide

Cat.No: T30206

Cat.No: T23781

Synonym: Akitan,Benztropine,NK 02,Cogentinol,Cogentine

Atropine iodomethylate

Cat.No: T30207

Cat.No: T33640

Synonym: W290,W 290,W-290

Atropine Oxide Hydrochloride

Cat.No: T69232

Ethybenztropine HBr

Cat.No: T69614

Methylatropine (nitrate)

Cat.No: T36204

Cat. No.	Product Name	Target	Signaling Pathways
T5595	Tropine 3alpha-Tropanol,托品醇,Pseudotropine	Others	Others
	Tropine 是一种茄科植物的次生代谢产物，是抗胆碱能试剂。它是一种常见的用于合成各种生物活性生物碱（如 hyoscyamine、scopolamine）的中间体。
PDK0060	Pseudotropine	Others	Others
	Pseudotropine 是一种植物生物碱，是 Tropane 的衍生物。
T1341	Nortropine Nortropenol,去甲托品醇	AChR	Neuroscience
	Nortropine (Nortropenol) 是托品碱分解和反应生成琥珀酸的中间体，可从Convolvulus subhirsutus 生物碱中分离得到。
T33717	Noratropine Norhyoscyamine
	Noratropine is a metabolite of Atropine (A794625).

天然产物

Cat.No: T5595

Synonym: 3alpha-Tropanol,托品醇,Pseudotropine

Target: Others

Cat.No: PDK0060

Target: Others

Cat.No: T1341

Synonym: Nortropenol,去甲托品醇

Target: AChR

Cat.No: T33717

Synonym: Norhyoscyamine

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