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58

抑制剂 & 化合物

2

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T37051	Tau tracer 2
	Tau tracer 2 (Pl-2620) is a specific imaging agent designed to detect and visualize Tau protein aggregates. Its primary application lies in the diagnosis of neurodegenerative diseases [1].
T39660	Tau tracer 1
	Tau tracer 1 is a radiopharmaceutical agent designed specifically for visualizing Tau protein aggregates, commonly associated with neurodegenerative diseases. Its primary application lies in the diagnosis of these conditions.
T19017	JAK2 JH2 Tracer	Others	Others
	JAK2 JH2 Tracer is a fluorescent probe for the JAK2 JH2 domain (Kd: 0.2 μM).
T19550	ROS tracer precursor	Others	Others
	ROS tracer precursor, the synthesis precursor for [18F]ROStrace, serves in the production of ROStrace. This compound is instrumental in disease diagnosis.
TD0092	Naphthoresorcinol 间萘二酚,1,3-二羟基萘,1,3-Dihydroxynaphthalene	Others	Others
	Naphthoresorcinol (1,3-Dihydroxynaphthalene) 是一种荧光染料 (λex=330 nm, λem=380 nm)，与 NPPD (一种示踪剂) 和浓 HCl 反应显示出红色。它也能够作为测定碳水化合物的背景电解质 (BGE) 。
T19963	Alizarin Complexone Alizarin Fluorine Blue,Alizarin-3-methyliminodiacetic acid,茜素络合指示剂	Reverse Transcriptase	Microbiology/Virology
	Alizarin Complexone (Alizarin-3-methyliminodiacetic acid) 是 Rous 相关病毒 2 逆转录酶的抑制剂。 Alizarin Complexone 可用作生物研究的钙示踪剂和螯合剂。
T4065	Fluorescein Sodium 荧光素钠,Fluorescite,VST-1001,Acid yellow 73,VST1001,VST 1001	Others	Others
	Fluorescein Sodium (VST-1001) 是一种具有代表性的绿色荧光示踪剂，广泛用于医学、生物应用和肿瘤感染组织的示踪剂，也可作为实用绿色荧光探针的支架。
T38968	GSHtracer
	GSHtracer is a ratiometric probe designed for the quantification of glutathione (GSH) concentrations. This probe demonstrates a measurable shift in its excitation-emission profile, specifically from 520/580 nm to 430/510 nm, upon binding with GSH.
T13151L	THK5351	Others	Others
	THK5351 是一种参与PET成像的示踪剂，参与阿尔茨海默病和认知障碍的电子发射断层扫描成像。
T77634	JHU 75528 JHU75528,JHU-75528	Cannabinoid Receptor	GPCR/G Protein
	JHU 75528 (JHU-75528) 是一种新型 PET 示踪剂，对 CB 具有抑制作用，可用于研究精神分裂症患者大麻素系统。
T19573	T807 AV-1451	Microtubule Associated	Cytoskeletal Signaling
	T807 (AV-1451) 是新型的tau 正电子发射断层扫描示踪剂。
T40418	DiO DiOC18(3),3,3'-Dioctadecyloxacarbocyanine perchlorate	Others	Others
	DiO (DiOC18(3)) 是一种荧光亲脂性示踪剂，可广泛用于标记细胞、细胞器、脂质体、病毒和脂蛋白。
T19261	D-Glucose-13C6 D-(+)-Glucose-13C6,Glucose-13C6,Dextrose-13C6	Endogenous Metabolite	Metabolism
	D-Glucose-13C6 (Dextrose-13C6) 是一种 D-Glucose 的同位素标记物，可作为代谢示踪剂，可用于研究机体代谢相关疾病和部分物质的代谢过程。
T21000	PiB 2-(4-(二甲基氨基)苯基)苯并[D]噻唑-6-醇,Pittsburgh Compound-B,6-OH-BTA-1	Others	Others
	PiB (Pittsburgh Compound-B) 是分析 11C-PiB 的标准品。 11C-PiB 是一种用于阿尔茨海默病诊断的 β-淀粉样蛋白 PET 成像示踪剂。
T26520	ABP688 ABP-688,ABP 688	GluR	Neuroscience
	ABP688 是一种非竞争性和选择性的 mGluR5 拮抗剂 (Ki = 1.7 nM)。 ABP688 可用作临床成像的 PET 示踪剂。
T1392	Fluorescein Solvent Yellow 94,Resorcinol phthalein,荧光素,Yellow fluorescein	Others	Others
	Fluorescein (Solvent Yellow 94) 是一种合成的有机光敏染料化合物，是一种荧光示踪剂，可以用于医学和生物学以及肿瘤感染的组织。
T39193	DOTATATE acetate
	DOTATATE acetate 是一种 DOTA 结合肽，是生长抑素类似物，也是一种新型 PET 示踪剂，参与评估高分化神经内分泌肿瘤（NET）的功能性成像。
T5848	Biocytin	Endogenous Metabolite	Metabolism
	Biocytin 是一种 D-生物素和 L-赖氨酸的共轭物，D-生物素的羧酸盐通过仲酰胺键与L-赖氨酸的 α-胺偶联。它是神经解剖学示踪剂，通常用于绘制大脑的连接性。它在顺逆行和细胞内神经解剖学研究以及生物素酶测定中用作通用标记物。
T38681	P-SCN-Bn-DOTA	Others	Others
	p-SCN-Bn-DOTA 是一种螯合剂，可同时螯合放射性核素和连接单克隆抗体，可作为放射引导手术的示踪剂，可用于肿瘤的放射免疫研究。
T28466	PSMA-11 HBED-CC-PSMA,Psma-hbed-CC,PSMA11
	PSMA-11 (HBED-CC-PSMA)通过与前列腺特异性膜抗原(PSMA)的细胞外结构域结合来检测前列腺癌的复发和转移。PSMA-11常被用作正电子发射断层扫描(PET)中用作表达PSMA 的肿瘤的示踪剂，通过静脉注射镓Ga 68标记的PSMA-11，Glu-urea-Lys(Ahx)分子靶向并结合表达PSMA 的肿瘤细胞。内化后，PSMA 表达的肿瘤细胞可在PET 成像中被检测到。
T33348	Methyl-d9-choline J2.078.736H
	Methyl -D9- choline is an isotopically labeled choline tracer.
T33890	PBB3 PBB-3,J3.303.052E,PBB 3
	PBB3 is a tau-specific PET tracer.
T27684	JNJ-42259152 JNJ42259152,JNJ 42259152
	JNJ-42259152 is a phosphodiesterase 10A PET tracer.
T31410	D-Fluoromethyltyrosine F-18 BAY 86 9596,BAY 869596,BAY 86-9596,J2.566.882K,BAY-86-9596 F-18
	Fluoroethyl-l-tyrosine (18F) or 18F-FET is a neuro-oncology PET tracer.
T32307	JNJ-42259152 F-18
	JNJ-42259152 F-18 can be used as a Novel Phosphodiesterase 10A PET Tracer.
T19143	4-(6-Bromo-2-benzothiazolyl)benzenamine	Others	Others
	4-(6-Bromo-2-benzothiazolyl)benzenamine is a β-amyloid PET tracer and can be used in the diagnosis of neurological diseases.
T34966	TUG-1609
	TUG-1609 is a fluorescent tracer of FFA2 with good spectral properties and high affinity.
T31040	CP-18 F-18 CP18 F-18,CP 18 F-18,(18F)-CP18
	CP-18 F-18 is a DEVD (the caspase 3 substrate recognition motif) that is an imaging tracer for caspase-3 activity in apoptotic cells.
T33947	PF-06445974 PF-6445974,PF6445974,PF06445974,PF 6445974
	PF-06445974 has good selectivity for PDE4D, excellent brain permeability, and has a high level of specific binding in the "cold tracer" study.
T29476	6-OH-BTA-0 Pittsburgh Compound-B precursor,11C-PiB Precursor
	6-OH-BTA-0 is the precursor for preparing 11C-PiB, which is a β-amyloid PET imaging tracer for Alzheimer's disease diagnosis.
T24956	(18F)LBT 999 (18F)LBT999,LBT999 18F,LBT 999 18F,LBT-999 18F,(18F)LBT-999
	(18F)LBT 999 is a positron emission tomography (PET) tracer, used for the quantification of the dopamine transporter (DAT) in the healthy rat brain.
T30444L	Bicisate (Free base) Bicisate
	Bicisate is usually complex with technetium Tc99m for its usage as a tracer to measure cerebral blood flow with single-photon emission computed tomography (SPECT).
T19429	MK-6240	Others	Others
	MK-6240 is a tau positron emission tomography (PET) tracer for neurofibrillary tangles (NFTs). MK-6240 exhibits high specificity and selectivity for binding to NFTs.
T34766	T-808 AVI-680
	T-808 is a tau tracer which may be used in radiographic labeling of Tau aggregates during Alzheimer's disease.
T37126	1,6-Anhydro-D-galactose
	1,6-Anhydro-D-galactose is a carbohydrate found in liquid smoke flavorings that is used as a tracer of the contribution of biomass burning to total atmospheric particulate matter.
T31787	Fet F-18 Fet F18,18F-Fluoroethyltyrosine,18F-FET
	Fet F-18 is an amino acid analog radiolabeled with fluorine F-18, a positron-emitting isotope, can be used as a tracer in positron emission tomography (PET).
T25292	DCCCyb
	DCCCyb is an orally bioavailable and selective GlyT1 Inhibitor. DCCCyb demonstrated excellent in vivo occupancy of GlyT1 transporters in rhesus monkeys as determined by the displacement of a PET tracer ligand.
T37667	True Blue
	True blue is a fluorescent neuronal retrograde tracer that labels the nucleus, nucleolus, cell body, proximal dendrites, and axons of neurons. It displays excitation/emission maxima of 373/404 nm, respectively.
T31389	Desmethyl-HD-800 Desmethyl-HD800,Desmethyl HD800
	Desmethyl-HD-800 is a PET precursor of preparing radiolabel [11C]HD-800, a high affinity brain penetrant PET tracer for imaging microtubules.
T78667	FAPI-74
	FAPI-74是一种专门针对成纤维细胞激活蛋白（FAP）的PET示踪剂，适用于FAP阳性肿瘤的研究。
T69660	NOTA-FAPI-4
	NOTA-FAPI-4 is an analogue of FAPI-4 and a fibroblast activation protein (FAP) inhibitor. NOTA-FAPI-4 is useful in the diagnosis or treatment of a disease characterized by overexpression of fibroblast activation protein (FAP). NOTA-FAPI-4 can be used as a PET tracer for detection of diseases or disorders related to fibroblast activation protein.
T25294	DCFBC F-18 18F-DCFBC
	DCFBC F-18 is a radioconjugate containing a low molecular weight tracer, DCFBC, specific for prostate-specific membrane antigen (PSMA) and labeled with the positron-emitting isotope F 18 with potential prostate tumor imaging upon positron emission tomogra
T39878	FFN270 hydrochloride FFN270 hydrochloride
	FFN270 hydrochloride, a fluorescent tracer for norepinephrine and vesicular monoamine transporters, features dual resolved absorption/excitation peaks that vary with solvent pH (FFN270 ex: 320 nm or 365 nm, em: 475 nm). It serves as a ratiometric fluorescent pH-sensor, highlighting its utility in monitoring norepinephrine.
T39119	Fluoroethylnormemantine hydrochloride
	Fluoroethylnormemantine hydrochloride, a Memantine derivative, functions as an antagonist for the N-methyl-D-aspartate (NMDA) receptor. It can also serve as a positron emission tomography (PET) tracer, specifically as [18F]-Fluoroethylnormemantine hydrochloride. Notably, this compound displays a range of effects, including anti-amnesic, neuroprotective, antidepressant-like, and fear-attenuating properties.
T39120	Fluoroethylnormemantine
	Fluoroethylnormemantine, a derivative of Memantine, acts as an N-methyl-D-aspartate (NMDA) receptor antagonist. It can function as a positron emission tomography (PET) tracer, known as [18F]-fluoroethylnormemantine. This compound displays anti-amnesic, neuroprotective, antidepressant-like, and fear-attenuating properties.
T81904	Lucifer yellow iodoacetamide dipotassium
	Lucifer yellow iodoacetamide dipotassium为一种反应性巯基荧光示踪剂，具备巯基与特定生物分子反应的能力，广泛应用于生物化学与分子生物学研究中。
T38638	4-Trifluoromethylsalicylic acid-13C6 4-Trifluoromethylsalicylic acid-13C6,Desacetyl triflusal-13C6
	4-Trifluoromethylsalicylic acid-13C6 是 13C 标记的 4-Trifluoromethylsalicylic acid，主要用于药物开发过程中的定量示踪剂。4-Trifluoromethylsalicylic acid 也是一种血小板聚集抑制剂。
T37607	Rhodamine B isothiocyanate (mixed isomers)
	Rhodamine B isothiocyanate (RITC) is a cell-permeant fluorogenic dye most often used as a conjugate to antibodies and proteins for fluorescence detection in microscopy. It displays excitation/emission maxima of 570/595 nm, respectively, and can be used in conjunction with immunohistochemistry for multi-labeling studies. It has also been used as an anterograde and retrograde tracer in neurons and in nanoparticles to detect apoptosis.
T81338	Pyrromethene 556 PM556
	Pyrromethene 556 (PM556) 是一种绿色荧光极性示踪染料。它应用于膜融合、溶解和隙缝连接通信的研究，以及探测细胞或脂质体体积变化。
T18988L1	FITC-Dextran (MW 60,000-76,000)
	FITC-Dextran (MW 60,000-76,000) 是一种异硫氰酸荧光素 (FITC)标记的葡聚糖荧光探针，常用作示踪分子来标记和跟踪细胞或其他生物物质对半透膜的作用。

化合物

Cat.No: T37051

Cat.No: T39660

JAK2 JH2 Tracer

Cat.No: T19017

Target: Others

ROS tracer precursor

Cat.No: T19550

Target: Others

Naphthoresorcinol

Cat.No: TD0092

Synonym: 间萘二酚,1,3-二羟基萘,1,3-Dihydroxynaphthalene

Target: Others

Alizarin Complexone

Cat.No: T19963

Synonym: Alizarin Fluorine Blue,Alizarin-3-methyliminodiacetic acid,茜素络合指示剂

Target: Reverse Transcriptase

Fluorescein Sodium

Cat.No: T4065

Synonym: 荧光素钠,Fluorescite,VST-1001,Acid yellow 73,VST1001,VST 1001

Target: Others

Cat.No: T38968

Cat.No: T13151L

Target: Others

Cat.No: T77634

Synonym: JHU75528,JHU-75528

Target: Cannabinoid Receptor

Cat.No: T19573

Synonym: AV-1451

Target: Microtubule Associated

Cat.No: T40418

Synonym: DiOC18(3),3,3'-Dioctadecyloxacarbocyanine perchlorate

Target: Others

Cat.No: T19261

Synonym: D-(+)-Glucose-13C6,Glucose-13C6,Dextrose-13C6

Target: Endogenous Metabolite

Cat.No: T21000

Synonym: 2-(4-(二甲基氨基)苯基)苯并[D]噻唑-6-醇,Pittsburgh Compound-B,6-OH-BTA-1

Target: Others

Cat.No: T26520

Synonym: ABP-688,ABP 688

Target: GluR

Cat.No: T1392

Synonym: Solvent Yellow 94,Resorcinol phthalein,荧光素,Yellow fluorescein

Target: Others

DOTATATE acetate

Cat.No: T39193

Cat.No: T5848

Target: Endogenous Metabolite

Cat.No: T38681

Target: Others

Cat.No: T28466

Synonym: HBED-CC-PSMA,Psma-hbed-CC,PSMA11

Methyl-d9-choline

Cat.No: T33348

Synonym: J2.078.736H

Cat.No: T33890

Synonym: PBB-3,J3.303.052E,PBB 3

Cat.No: T27684

Synonym: JNJ42259152,JNJ 42259152

D-Fluoromethyltyrosine F-18

Cat.No: T31410

Synonym: BAY 86 9596,BAY 869596,BAY 86-9596,J2.566.882K,BAY-86-9596 F-18

JNJ-42259152 F-18

Cat.No: T32307

4-(6-Bromo-2-benzothiazolyl)benzenamine

Cat.No: T19143

Target: Others

Cat.No: T34966

Cat.No: T31040

Synonym: CP18 F-18,CP 18 F-18,(18F)-CP18

Cat.No: T33947

Synonym: PF-6445974,PF6445974,PF06445974,PF 6445974

Cat.No: T29476

Synonym: Pittsburgh Compound-B precursor,11C-PiB Precursor

Cat.No: T24956

Synonym: (18F)LBT999,LBT999 18F,LBT 999 18F,LBT-999 18F,(18F)LBT-999

Bicisate (Free base)

Cat.No: T30444L

Synonym: Bicisate

Cat.No: T19429

Target: Others

Cat.No: T34766

Synonym: AVI-680

1,6-Anhydro-D-galactose

Cat.No: T37126

Cat.No: T31787

Synonym: Fet F18,18F-Fluoroethyltyrosine,18F-FET

Cat.No: T25292

Cat.No: T37667

Desmethyl-HD-800

Cat.No: T31389

Synonym: Desmethyl-HD800,Desmethyl HD800

Cat.No: T78667

Cat.No: T69660

Cat.No: T25294

Synonym: 18F-DCFBC

FFN270 hydrochloride

Cat.No: T39878

Synonym: FFN270 hydrochloride

Fluoroethylnormemantine hydrochloride

Cat.No: T39119

Fluoroethylnormemantine

Cat.No: T39120

Lucifer yellow iodoacetamide dipotassium

Cat.No: T81904

4-Trifluoromethylsalicylic acid-13C6

Cat.No: T38638

Synonym: 4-Trifluoromethylsalicylic acid-13C6,Desacetyl triflusal-13C6

Rhodamine B isothiocyanate (mixed isomers)

Cat.No: T37607

Pyrromethene 556

Cat.No: T81338

Synonym: PM556

FITC-Dextran (MW 60,000-76,000)

Cat.No: T18988L1

Cat. No.	Product Name	Target	Signaling Pathways
T7975	Rhodamine B 罗丹明B,Rhodamine B,罗丹明 B,Tetraethylrhodamine,Brilliant Pink B,Basic Violet 1,Rhodamine O	Others	Others
	Rhodamine B (Brilliant Pink B) 是荧光染料，常用于染色纺织品、肥皂、纸张、皮革和药品。
TN2203	Senecionine N-oxide Senecionine oxide
	Senecionine n-oxide 是千里光寻常型根部培养物中吡咯烷核生物碱生物合成的主要产物，Senecionine N-oxide (Senecionine oxide) 具有抗肿瘤活性，但可诱导肝窦阻塞综合征。Senecionine n-oxide可作为 N-氧化物螯合示踪剂。

天然产物

Cat.No: T7975

Synonym: 罗丹明B,Rhodamine B,罗丹明 B,Tetraethylrhodamine,Brilliant Pink B,Basic Violet 1,Rhodamine O

Target: Others

Senecionine N-oxide

Cat.No: TN2203

Synonym: Senecionine oxide

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