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Cat. No.	Product Name	Target	Signaling Pathways
T1092	Zolmitriptan 佐米曲普坦,311C90,BW-311C90	5-HT Receptor	GPCR/G Protein; Neuroscience
	Zolmitriptan (311C90) 是一种5-HT1B/1D 受体部分激动剂，可用于偏头痛的研究，对 5-HT1B、5-HT1D、5-HT1F 受体的Ki 分别为 5.01、0.63 和 63.09 nM。
T1509	Cyclobenzaprine hydrochloride 盐酸环苯扎林,Cyclobenzaprine HCl,MK130 hydrochloride	5-HT Receptor	GPCR/G Protein; Neuroscience
	Cyclobenzaprine hydrochloride (MK130 hydrochloride) 是一种具有抗抑郁活性的中枢作用肌肉松弛剂，可减少肌肉痉挛。
T21447	Tolazoline Priscol,妥拉苏林,Priscoline,Pridazole,Divascol,Vasimid,Benzalolin	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Tolazoline (Benzalolin) 是一种竞争性的α-肾上腺素受体拮抗剂。
T33846	Oxyphenonium bromide Spasmophen,Oxifenon,奥芬溴铵,Oxyfenon,Atrenyl,Oxyphenon	Others	Others
	Oxyphenonium bromide (Oxyfenon) 具有抗胆碱能活性，可用于治疗胃和十二指肠溃疡以及缓解内脏痉挛的研究。
T1475	Fesoterodine fumarate Toviaz,SPM 907,富马酸非索罗定	AChR	Neuroscience
	Fesoterodine fumarate (Toviaz) 是可口服的，非亚型选择性的竞争性毒蕈碱受体拮抗剂，用于膀胱过度活动症，对 M1、M2、M3、M4 和 M5 受体的pKi 值分别为 8.0、7.7、7.4、7.3 和 7.5。
T1065	Baclofen 巴氯芬,Lioresal	GABA Receptor	Membrane transporter/Ion channel; Neuroscience
	Baclofen (Lioresal) 是 γ-氨基丁酸 (GABA) 的亲脂性衍生物，是可口服的选择性代谢型 GABA-B 受体激动剂，具有高血脑屏障渗透率，用于治疗因脊髓损伤和多发性硬化引起的痉挛。
T0786	Clidinium bromide 克利溴铵,Ro 2-3773	AChR	Neuroscience
	Clidinium bromide (Ro 2-3773) 是季胺抗毒蕈碱剂，可通过减少胃酸和减慢肠道速度，缓解痉挛和腹部疼痛的症状。
T34121	Pramiverine EMD 9806,HSP 2986,EMD9806,HSP2986,EMD-9806
	Pramiverine is a long-acting choline dissolving agent used for gastrointestinal spasms.
T21376	Chlorphenesin Carbamate Kolpicortin-sine,Rinlaxer,Chlorphensin carbamate,Maolate,氯苯氨酸甘油酯,laChlorphenesin Carbamate
	Chlorphenesin Carbamate is a centrally acting muscle relaxant used to treat muscle pain and spasms and also an antifungal agent.
T25654	Leiopyrrole Leioplegil,DV 714,Leiopyrrolum,DV714,DV-714
	Leiopyrrole 是一种抗胆碱能化合物，能够用于解痉挛。
T70153	Pipoxolan hydrochloride
	Pipoxolan (HCl) is an antispasmodic drug. In vivo, the drug inhibited the contractions of intestines caused by neostigmine, barium chloride or injection of acetylcholine. The drug possesses ganglioplegic action and inhibited the decrease in blood pressure caused by stimulation of the vagus nerve. The drug is marketed under tradename Rowapraxin worldwide for the treatment of spasms and colics in the gastrointestinal tract, gallbladder and urogenital area, bronchial spasms, spastic menstrual cramp...
T29000	Tralomethrin EPA Pesticide Chemical Code 121501,SAGA,HAG-107,HAG 107,Scout
	Tralomethrin is used as a pyrethroid insecticide. It modifies the gating kinetics of the sodium channels in neurons, increases the length of time the channel remains open after a stimulus, thereby depolarizing the neuron for a longer period of time. This leads to uncontrolled spasms, paralysis, and eventual death.
T61453	Propantheline
	Propantheline is an orally active antagonist of muscarinic acetylcholine receptors (mAChRs), commonly employed to investigate smooth muscle dysfunction, hyperhidrosis, smooth muscle spasms or cramps in the stomach, intestines, or bladder, as well as involuntary urination [1] [2] [3].
T69661	Pipoxolan (free base)
	Pipoxolan (free base) is an antispasmodic drug. In vivo, the drug inhibited the contractions of intestines caused by neostigmine, barium chloride or injection of acetylcholine. The drug possesses ganglioplegic action and inhibited the decrease in blood pressure caused by stimulation of the vagus nerve. The drug is marketed under tradename Rowapraxin worldwide for the treatment of spasms and colics in the gastrointestinal tract, gallbladder and urogenital area, bronchial spasms, spastic menstrual...
T33314	Methantheline Bromide Frenogastrico,Dixamone bromide,Banthine,Asabaine,Methanthelinium bromide
	Methantheline Bromide is a synthetic spasmolytic used to relieve cramps or spasms of the stomach, bowel, and bladder. It is also useful for intestinal or gastric ulcers (peptic ulcer disease), intestinal problems, pancreatitis, gastritis, biliary dysmotil
T25325	Dicyclonon LAB 145-138H,BAS 145-138
	Dicyclonon is a muscarinic antagonist utilized as an antispasmodic and in urinary incontinence. It has little effect on glandular secretion or the cardiovascular system. It has some local anesthetic properties and is utilized in biliary, gastrointestinal,
T37950	2-(Isopentylamino)naphthalene-1,4-dione
	2-(Isopentylamino)naphthalene-1,4-dione is a vitamin K analog.1It inhibits spasms induced by pentylenetetrazole and tonic hindlimb extension induced by maximal electroshock (MES) in mice (ED50s = 349.2 and 108.1 mg/kg, respectively). It also protects mice against seizures in the 6 Hz psychomotor seizure test (ED50s = 152.7 and 263.7 mg/kg at stimulus intensities of 32 and 44 mA, respectively). 1.Li, X., Himes, R.A., Prosser, L.C., et al.Discovery of the first vitamin K analogue as a potential tr...

化合物

Cat.No: T1092

Synonym: 佐米曲普坦,311C90,BW-311C90

Target: 5-HT Receptor

Cyclobenzaprine hydrochloride

Cat.No: T1509

Synonym: 盐酸环苯扎林,Cyclobenzaprine HCl,MK130 hydrochloride

Target: 5-HT Receptor

Cat.No: T21447

Synonym: Priscol,妥拉苏林,Priscoline,Pridazole,Divascol,Vasimid,Benzalolin

Target: Adrenergic Receptor

Oxyphenonium bromide

Cat.No: T33846

Synonym: Spasmophen,Oxifenon,奥芬溴铵,Oxyfenon,Atrenyl,Oxyphenon

Target: Others

Fesoterodine fumarate

Cat.No: T1475

Synonym: Toviaz,SPM 907,富马酸非索罗定

Target: AChR

Cat.No: T1065

Synonym: 巴氯芬,Lioresal

Target: GABA Receptor

Clidinium bromide

Cat.No: T0786

Synonym: 克利溴铵,Ro 2-3773

Target: AChR

Cat.No: T34121

Synonym: EMD 9806,HSP 2986,EMD9806,HSP2986,EMD-9806

Chlorphenesin Carbamate

Cat.No: T21376

Synonym: Kolpicortin-sine,Rinlaxer,Chlorphensin carbamate,Maolate,氯苯氨酸甘油酯,laChlorphenesin Carbamate

Cat.No: T25654

Synonym: Leioplegil,DV 714,Leiopyrrolum,DV714,DV-714

Pipoxolan hydrochloride

Cat.No: T70153

Cat.No: T29000

Synonym: EPA Pesticide Chemical Code 121501,SAGA,HAG-107,HAG 107,Scout

Cat.No: T61453

Pipoxolan (free base)

Cat.No: T69661

Methantheline Bromide

Cat.No: T33314

Synonym: Frenogastrico,Dixamone bromide,Banthine,Asabaine,Methanthelinium bromide

Cat.No: T25325

Synonym: LAB 145-138H,BAS 145-138

2-(Isopentylamino)naphthalene-1,4-dione

Cat.No: T37950

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