Cat. No. | Product Name | Target | Signaling Pathways |
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TP1703 |
FliC, Serotype a (427-441), S.paratyphi A
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This is amino acids 427 to 441 fragment belongs to the FliC, serotype a of the S. FliC epitope recognized by a CD4+ T cell from naturally infected C57BL/6 mice is located in a region common to a number of distinct Salmonella serovars such as the S. paraty | |||
T0688 |
Ganciclovir
BW 759,更昔洛韦,RS-21592,2'-Nor-2'-deoxyguanosine |
Nucleoside Antimetabolite/Analog; Others; Antibiotic; Antifection; HSV | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Others |
Ganciclovir (2'-Nor-2'-deoxyguanosine) 是核苷类似物和口服抗病毒药物,对CMV 具有抗病毒活性。它用于治疗与艾滋病相关的巨细胞病毒感染的并发症。 | |||
T22337 |
Ganciclovir sodium
RS-21592 sodium,Cytovene IV sodium,2'-Nor-2'-deoxyguanosine sodium,BW 759 sodium,更昔洛韦钠 |
Nucleoside Antimetabolite/Analog; Others; Antifection; HSV | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Others |
Ganciclovir sodium (Cytovene IV sodium) 是核苷类似物和口服抗病毒药物,具有抗病毒活性,尤其是针对巨细胞病毒和单纯疱疹病毒 1 型。 | |||
T26937 | C562-1101 | ||
C562-1101 is a novel potent botulinum neurotoxin serotype E (BoNT/E) inhibitor. | |||
T26961 |
CBIP
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CBIP is a small-molecule inhibitors of botulinum neurotoxin serotype A light chain (BoNT/A LC). CBIP possesses low micromolar activity against BoNT/A. | |||
T69649 |
NITD-688
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NITD-688 是一种具有口服活性的登革病毒 (dengue virus)NS4B 蛋白的泛血清型抑制剂。 NITD-688 可用于登革热病毒 (DENV) 的研究。 | |||
T76755 | Panobacumab | ||
Panobacumab (KBPA101) 是一种完全人 IgM/κ 单克隆抗体,由人类 B 淋巴细胞产生,对血清型 O11P. aeruginosa 的 LPS O 多糖具有抗性。 | |||
T79141 |
Mosnodenvir
JNJ-1802 |
Virus Protease | Microbiology/Virology |
Mosnodenvir(JNJ-1802)是一种泛血清型登革热抗病毒药物,表现出较高的耐药性屏障,同时安全性和耐受性均优良。它通过阻断NS3-NS4B相互作用来抑制病毒复制复合体。在小鼠模型中,Mosnodenvir展示了从皮摩尔到低纳摩尔量级的体外抗病毒效能。 | |||
T36862 |
Ganglioside GT1b Mixture (sodium salt)
Ganglioside GT1b Mixture (sodium salt),Ganglioside G1 Mixture |
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Ganglioside GT1b is a trisialoganglioside that is characterized by having two sialic residues linked to the inner galactose unit. It binds to the neurotoxins botulinum toxin serotype A (BTxA), BTxA heavy chain, and tetanus toxin with IC50 values of 11, 0.74, and 7.2 μM, respectively.[1] Ganglioside GT1b-containing liposomes bind to the major coat protein VP1 from Merkel cell polyomavirus (MCPyV), which has been identified in Merkel cell carcinomas, identifying ganglioside GT1b as a putative MCP... | |||
T83695 |
MOG Peptide (human, bovine) acetate
Myelin Oligodendrocyte Glycoprotein Peptide |
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Myelin Oligodendrocyte Glycoprotein (MOG) peptide 是 MOG 的一种内源性肽段截取,存在于髓鞘的细胞外表面。当与抗原血清型HLA-DR2结合时,MOG peptide 在通过中脑动脉阻塞(MCAO)诱导的缺血性中风模型中,能减少皮层和纹状体梗死体积,降低管-角转测试中的感觉运动障碍,增加对新奇气味的探索时间,以及增加雌性(但不是雄性)小鼠对笼伴侣发出的呼叫持续时间。 | |||
T83704 |
A20FMDV2 TFA
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A20FMDV2是一种由口蹄疫病毒(FMDV)血清型O的VP1衣壳蛋白上的α-螺旋RGD细胞相互作用域组成的肽,能够结合到αVβ6整合素上。该化合物在表达人αVβ6的H357舌鳞状细胞癌细胞中抑制αVβ6整合素依赖的细胞粘附(IC50 = 1.2 µM)。与111indium-DTPA耦合时,A20FMDV2(20 MBq)可结合于在乳腺癌小鼠异种移植模型中内源性表达的αVβ6整合素,用于放射成像分析。 | |||
T37901 |
UDP-N-acetyl-D-Glucosamine (sodium salt hydrate)
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UDP-N-acetyl-D-Glucosamine is a natural nucleotide sugar that is used by glycosyltransferases to transfer N-acetyl-D-glucosamine residues to substrates.1It is an important component of antibiotic biosynthesis pathways in fungi and lipopolysaccharide production in bacteria.2,3 1.Roseman, S.Reflections on glycobiologyJ. Biol. Chem.276(45)41527-41542(2001) 2.Kudo, F., and Eguchi, T.Biosynthetic genes for aminoglycoside antibioticsJ. Antibiot. (Tokyo)62(9)471-481(2009) 3.Mulrooney, E.F., Poon, K.K.,... | |||
T37347 |
6'-Sialyllactose Sodium Salt
6'-Sialyllactose Sodium Salt,6'-N-Acetylneuraminyl-D-lactose |
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6'-Sialyllactose consists of the monosaccharide N-acetylneuraminic acid linked to the galactosyl subunit of lactose at the 6 position. This connection is at the 3 position in the related compound, 3’-sialyllactose. Both are major milk oligosaccharides that avidly bind several viral strains, including strains of influenza, HIV-1, reovirus, and polyomavirus.[1],[2],[3],[4],[5],[6] These compounds can be used to differentiate and characterize the binding domains of viruses that recognize N-acetylne... |