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抑制剂 & 化合物

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T5326	Sugammadex sodium Org25969,Sugammadex (sodium),舒更葡糖钠	Others	Others
	Sugammadex sodium (Org25969) 是合成的 γ 环糊精衍生物，是一种新型的神经肌肉阻断逆转剂。
T10820L1	Ciraparantag acetate Ciraparantag acetate(1438492-26-2 Free base)	Others	Others
	Ciraparantag acetate 是一种抗凝逆转剂，是一种小分子，专门设计用于通过电荷-电荷相互作用与普通肝素和低分子量肝素非共价结合。它显示出与直接口服抗凝剂 (DOAC) 相似的结合特性。
T10820	Ciraparantag PER977	Others	Others
	Ciraparantag is an inhibitor of thrombin and factor Xa. Ciraparantag is a broad-spectrum reversal agent for anticoagulants, including unfractionated heparin, low-molecular-weight heparin, and certain direct oral anticoagulants.
T82083	Idarucizumab BI 655075
	Idarucizumab 是一种专门中和口服直接凝血酶抑制剂（DOAC）效用的人源化单克隆抗体片段，是首个用于逆转DOAC抗凝作用的逆转剂（reversal agent），适用于恢复正常止血功能。
T10820L	Ciraparantag TFA PER977 TFA	Others	Others
	Ciraparantag TFA is an inhibitor of thrombin and factor Xa. Ciraparantag is a broad-spectrum reversal agent for anticoagulants, including unfractionated heparin, low-molecular-weight heparin, and certain direct oral anticoagulants.
T5326L	Sugammadex Org-25969,Org25969,Org 25969,361LPM2T56
	Sugammadex is an agent for reversal of neuromuscular blockade by the agent rocuronium in general anaesthesia. It is the first selective relaxant binding agent (SRBA). Sugammadex is a modified γ-cyclodextrin, with a lipophilic core and a hydrophilic periph

化合物

Sugammadex sodium

Cat.No: T5326

Synonym: Org25969,Sugammadex (sodium),舒更葡糖钠

Target: Others

Ciraparantag acetate

Cat.No: T10820L1

Synonym: Ciraparantag acetate(1438492-26-2 Free base)

Synonym: BI 655075

Target:

Ciraparantag TFA

Cat.No: T10820L

Synonym: PER977 TFA

Target: Others

Sugammadex

Cat.No: T5326L

Synonym: Org-25969,Org25969,Org 25969,361LPM2T56

Target:

Cat. No.	Product Name	Target	Signaling Pathways
T3924	Astragaloside II 黄芪皂苷 II,Astrasieversianin VIII	TGF-beta/Smad	Stem Cells
	Astragaloside II (Astrasieversianin VIII) 是一种分离自黄芪中的天然化合物。
T4A2399	Cinobufotalin 华蟾毒它灵,华蟾素	IL Receptor; Akt; MRP; P-gp	Cytoskeletal Signaling; Immunology/Inflammation; Membrane transporter/Ion channel; Neuroscience; PI3K/Akt/mTOR signaling
	Cinobufotalin 是一种从蟾蜍的皮肤分泌物中提取的强心类固醇或丁二烯内酯。它已被用作强心药，利尿药和止血药，也是潜在的抗肺癌药物。
T23610	Acerinol
	Acerinol is an active ingredient from traditional Chinese medicinal herbs. It could be used as a cancer multidrug resistance reversal agent. Acerinol can significantly stimulate the activity of ABCB1 ATPase without affecting the expression of ABCB1 on nei
T83055	Anti-inflammatory agent 57
	Anti-inflammatory agent 57（Compound 13），一种天然产自Peucedanum praeruptorum根部的吡喃香豆素，既能逆转多药耐药性（MDR）又具备抗炎效果。