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27

抑制剂 & 化合物

3

天然产物

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Cat. No. Product Name Target Signaling Pathways
T4190 Ticlopidine

PCR 5332,Ticlid,噻氯匹定

ATPase; Adiponectin receptor GPCR/G Protein; Membrane transporter/Ion channel
Ticlopidine (PCR 5332) 是抗血栓前药。它是CYP2C19人肝细胞色素的抑制剂,抑制 CYP2C9 及 CYP3A4。他是变构CD39的非竞争性抑制剂,能够阻断 NTPDase 同工酶,对NTPDase2和NTPDase3的IC50分别为 170 µM 和 149 µM。
T0230 Prasugrel

LY640315,CS-747,普拉格雷,PCR 4099

P2Y Receptor GPCR/G Protein; Neuroscience
Prasugrel (CS-747) 是一种噻吩吡啶和前药,是一种可口服的 P2Y12受体拮抗剂,抑制 ADP 诱导的血小板聚集,用于预防急性冠状动脉综合征患者的血栓形成、不稳定型心绞痛和心肌梗塞,以及接受经皮冠状动脉介入治疗的患者。
T6952 Prasugrel Hydrochloride

LY 640315,PCR 4099 (hydrochloride),盐酸普拉格雷,Effient Hydrochloride,LY 640315 Hydrochloride,Prasugrel HCl

P2Y Receptor GPCR/G Protein; Neuroscience
Prasugrel Hydrochloride (LY 640315 Hydrochloride) 是一种噻吩吡啶和前药,是一种可口服的P2Y12受体拮抗剂,抑制 ADP 诱导的血小板聚集,用于预防急性冠状动脉综合征患者的血栓形成、不稳定型心绞痛和心肌梗塞,以及接受经皮冠状动脉介入治疗的患者。
T16572 Prasugrel (Maleic acid)

马来酸普拉格雷,PCR 4099 (Maleic acid)

Prasugrel Maleic acid is an orally active and potent P2Y12 receptor antagonist and inhibits ADP-induced platelet aggregation. Prasugrel Maleic acid is a thienopyridine and prodrug. Prasugrel Maleic acid also inhibits platelet function.
T19062 Sulforhodamine 101

磺基罗丹明101,磺基罗丹明 101,SR101

Others Others
Sulforhodamine 101 (SR101) 是一种两性罗丹明红色荧光染料 (excitation/emission: 586/605 nm),常用于神经元形态的研究,并作为星形胶质细胞的细胞类型选择性荧光标记物,在体内和切片制备中都有应用。
T8936 Proteinase K

proteinase K for tritirachium album,Protease K,蛋白酶 K

Others Others
Proteinase K (proteinase K for tritirachium album) 是一种非特异性丝氨酸蛋白酶,可用于蛋白消化。它在有 SDS 或尿素存在的情况下,在很大 pH 值 (4-12)、盐浓度和温度单位内均有活性。
T40685L Orphan GPCR SP9155 agonist P550 (mouse, rat) acetate

Orphan GPCR SP9155 agonist P550 (mouse, rat) acetate (600171-70-8 Free base)

Others Others
Orphan GPCR SP9155 agonist P550 (mouse, rat) acetate (Orphan GPCR SP9155 agonist P550 ) 是具有促食欲作用的 RFamide 肽家族的成员。
T60074 GPCR agonist-2

4-(Cyclopropylamino)-3-nitrobenzoic acid

GPR Endocrinology/Hormones; GPCR/G Protein
GPCR agonist-2 (4-(Cyclopropylamino)-3-nitrobenzoic acid) 是人源 GPCR GPR109B 的激动剂。
T40685 Orphan GPCR SP9155 agonist P550 (mouse, rat)

26RFa (mouse, rat),Orphan GPCR SP9155 agonist P550 (mouse, rat)

Orphan GPCR SP9155 agonist P550 (mouse, rat) (26RFa (mouse, rat)) is an orphan GPCR with an orexigenic effect belonging to the RFamide peptide family. It acts as the cognate ligand for the mouse orphan receptor GPR103, which is also known as SP9155 or AQ27.
TP1847 GLGPNPCRKKCYKRDFLGR

GLGPNPCRKKCYKRDFLGR is a synthetic peptide.
T65636 BIS-TRIS propane

BTP

Others Others
BIS-TRIS propane (BTP) 是镍基和钴基自旋团簇的新型多齿配体,是一种金属螯合剂。Bis-tris propane 常作为两性离子缓冲液使用,可用于PCR、蛋白质结晶研究和MgATPase 酶活力研究。
TD0082 EDANS sodium

EDANS sodium salt,EDANS sodium salt [5-((2-Aminoethyl)amino)naphthalene-1-sulfonic acid, sodium salt],5-(2-氨乙基氨)-1-萘磺酸钠盐,5-(2-Aminoethylamino)-1-naphthalenesulfonic acid sodium salt,N-(Aminoethyl)-5-naphthylamine-1-sulfonic Acid Sodium Salt

Others Others
EDANS sodium (5-(2-Aminoethylamino)-1-naphthalenesulfonic acid sodium salt) 是开发基于 FRET 的核酸探针的供体,该探针广泛用于实时 PCR 测定。
T36688 Deoxyguanosine triphosphate trisodium salt

Deoxyguanosine 5-triphosphate,2'-Deoxyguanosine-5'-triphosphate trisodium salt,dGTP trisodium salt

Nucleoside Antimetabolite/Analog Cell Cycle/Checkpoint; DNA Damage/DNA Repair
Deoxyguanosine triphosphate trisodium salt (2'-Deoxyguanosine-5'-triphosphate trisodium salt) 是细胞中用于 DNA 合成的核苷酸前体,可用于逆转录聚合酶链反应 (RT-PCR) 中以进行 DNA 扩增。
T41255 Specific PXR antagonist 70

Others Others
Specific PXR antagonist 70 是一种特异性孕烷 X 受体 (PXR) 拮抗剂,对人源 PXR 的 IC50 为 540 nM,Ki 为 390 nM,可增强癌细胞的化学敏感性。
T80644 DNA polymerase-IN-1

Antiviral; DNA/RNA Synthesis Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Immunology/Inflammation
DNA polymerase-IN-1 作为DNA聚合酶抑制剂,展现出对肿瘤细胞的抗增殖活性,其半抑制浓度(IC50)为20.7 μM。DNA polymerase-IN-1 抑制 Taq DNA 聚合酶,IC 值低于 250μM。DNA polymerase-IN-1 通过RT-PCR检测在体外显示出抗逆转录病毒活性,可用于研究氧化损伤和结直肠癌。
T7518 Deoxycytidine triphosphate trisodium salt

2'-脱氧胞苷-5'-三磷酸三钠盐,2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE TRISODI

Nucleoside Antimetabolite/Analog; DNA/RNA Synthesis; Endogenous Metabolite; Antibiotic Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology
Deoxycytidine triphosphate trisodium salt (2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE TRISODI) 是可用于 DNA 合成的核苷三磷酸,可用于实时荧光定量 PCR、cDNA 合成和 DNA 测序。
TD0086 ROX Reference Dye

ROX Reference Dye was designed to standardize fluorescent reporter gene signals in real-time quantitative PCR or RT-PCR
T79922 Taq DNA polymerase

DNA/RNA Synthesis Cell Cycle/Checkpoint; DNA Damage/DNA Repair
Taq DNA 聚合酶是一种在PCR过程中广泛使用的耐热性酶,由Thermus aquaticus细菌产生,其功能是在高温下合成DNA链。
T18897 5(6)-ROX

5(6)-Carboxy-X-rhodamine

Others Others
5(6)-ROX, a nucleic acid fluorescent label, serves as a reference dye in real-time polymerase chain reaction (PCR) applications.
T41104 dUTP sodium

2'-Deoxyuridine-5'-triphosphate sodium salt

dUTP sodium is used for PCR.
T1405L Cefditoren sodium

Cefditoren pivoxil,Cefditoren,ME-1206,ME1206,ME 1206

Cefditoren sodium is a cephalosporin antibiotic potentially for the treatment of bacterial infection. The expression levels of Mrp2, Bcrp, Oat2 mRNA were markedly increased, while P-gp and Oct1 mRNA were decreased. In concordance with RT-PCR results, Mrp2
T75343 ​JOE

JOE,作为一种荧光染料,主要应用于 DNA 测序、PCR 以及 LCR 扩增。其吸光度和发射波长分别为 525 nm 和 550 nm。
T83668 Nucleic Acid Dye Green I

NucGel Green I Nucleic Acid Gel Stain,Green I Nucleic Acid Gel Stain

Nucleic Acid Dye Green I是一种不可渗透细胞的荧光染料,通常用于双链DNA和单链DNA的定量分析。它的激发和发射峰值分别为497 nm和520 nm。Nucleic Acid Dye Green I也被用于基因表达和RT-PCR检测。
TD0003L CelGreen nucleic acid gel stain *10,000× concentrate in DMSO*

CelGreen nucleic acid gel stain *10,000× concentrate in DMSO* is a fluorescent dye with a unique involvement that binds to all dsDNA double helix sulcus regions.In the free state, the side strand and CelGreen emit weak fluorescence, but the fluorescence is greatly enhanced once they are combined with the double-stranded DNA. Therefore, the fluorescence signal strength of CelGreen is related to the amount of double-stranded DNA, and the amount of double-stranded DNA in the PCR system can be detec...
T69269 DMGF

DMGF, also known as 7,7-dimethoxyagastisfavone, is a biflavonoid isolated from Taxus × media cv. Hicksii. DMGF induces apoptotic and autophagic cell death. DMGF could effectively attenuate the motility of B16F10 cells, and the results of real-time PCR revealed that DMGF also suppressed the expressions of matrix metalloproteinase-2 (MMP-2). MGF can inhibit the metastasis of highly invasive melanoma cancer cells through the down-regulation of F-actin polymerization DMGF may be further developed to...
TD0003 CelGreen nucleic acid gel stain *10,000× concentrate in water*

Others Others
CelGreen 是一种具有独特参与性的荧光染料,可与所有 dsDNA 双螺旋沟区域结合。在游离状态下,侧链和 CelGreen 发出微弱的荧光,但一旦与双链DNA 结合,荧光就会大大增强。因此,CelGreen 的荧光信号强度与双链DNA 的量有关,可以根据荧光信号检测PCR 系统中双链DNA 的量。
T37106 2'-Deoxyadenosine-5'-triphosphate (sodium salt hydrate)

2'-Deoxyadenosine-5'-triphosphate (dATP) is a purine nucleotide and derivative of the nucleic acid adenosine 5'-triphosphate .1dATP is a substrate for DNA polymerase in the synthesis of DNA.2It is a noncompetitive inhibitor of ribonucleotide reductases, which provides feedback inhibition during DNA synthesis.1dATP has commonly been used in DNA synthesis, sequencing, and labeling in research applications.3,4dATP accumulates in adenosine deaminase deficiency, a disorder characterized by mutations ...

化合物

Ticlopidine
Cat.No: T4190
Synonym: PCR 5332,Ticlid,噻氯匹定
Target: ATPase, Adiponectin receptor
Prasugrel
Cat.No: T0230
Synonym: LY640315,CS-747,普拉格雷,PCR 4099
Target: P2Y Receptor
Prasugrel Hydrochloride
Cat.No: T6952
Synonym: LY 640315,PCR 4099 (hydrochloride),盐酸普拉格雷,Effient Hydrochloride,LY 640315 Hydrochloride,Prasugrel HCl
Target: P2Y Receptor
Prasugrel (Maleic acid)
Cat.No: T16572
Synonym: 马来酸普拉格雷,PCR 4099 (Maleic acid)
Target:
Sulforhodamine 101
Cat.No: T19062
Synonym: 磺基罗丹明101,磺基罗丹明 101,SR101
Target: Others
Proteinase K
Cat.No: T8936
Synonym: proteinase K for tritirachium album,Protease K,蛋白酶 K
Target: Others
Orphan GPCR SP9155 agonist P550 (mouse, rat) acetate
Cat.No: T40685L
Synonym: Orphan GPCR SP9155 agonist P550 (mouse, rat) acetate (600171-70-8 Free base)
Target: Others
GPCR agonist-2
Cat.No: T60074
Synonym: 4-(Cyclopropylamino)-3-nitrobenzoic acid
Target: GPR
Orphan GPCR SP9155 agonist P550 (mouse, rat)
Cat.No: T40685
Synonym: 26RFa (mouse, rat),Orphan GPCR SP9155 agonist P550 (mouse, rat)
Target:
GLGPNPCRKKCYKRDFLGR
Cat.No: TP1847
Synonym:
Target:
BIS-TRIS propane
Cat.No: T65636
Synonym: BTP
Target: Others
EDANS sodium
Cat.No: TD0082
Synonym: EDANS sodium salt,EDANS sodium salt [5-((2-Aminoethyl)amino)naphthalene-1-sulfonic acid, sodium salt],5-(2-氨乙基氨)-1-萘磺酸钠盐,5-(2-Aminoethylamino)-1-naphthalenesulfonic acid sodium salt,N-(Aminoethyl)-5-naphthylamine-1-sulfonic Acid Sodium Salt
Target: Others
Deoxyguanosine triphosphate trisodium salt
Cat.No: T36688
Synonym: Deoxyguanosine 5-triphosphate,2'-Deoxyguanosine-5'-triphosphate trisodium salt,dGTP trisodium salt
Target: Nucleoside Antimetabolite/Analog
Specific PXR antagonist 70
Cat.No: T41255
Synonym:
Target: Others
DNA polymerase-IN-1
Cat.No: T80644
Synonym:
Target: Antiviral, DNA/RNA Synthesis
Deoxycytidine triphosphate trisodium salt
Cat.No: T7518
Synonym: 2'-脱氧胞苷-5'-三磷酸三钠盐,2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE TRISODI
Target: Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis, Endogenous Metabolite, Antibiotic
ROX Reference Dye
Cat.No: TD0086
Synonym:
Target:
Taq DNA polymerase
Cat.No: T79922
Synonym:
Target: DNA/RNA Synthesis
5(6)-ROX
Cat.No: T18897
Synonym: 5(6)-Carboxy-X-rhodamine
Target: Others
dUTP sodium
Cat.No: T41104
Synonym: 2'-Deoxyuridine-5'-triphosphate sodium salt
Target:
Cefditoren sodium
Cat.No: T1405L
Synonym: Cefditoren pivoxil,Cefditoren,ME-1206,ME1206,ME 1206
Target:
​JOE
Cat.No: T75343
Synonym:
Target:
Nucleic Acid Dye Green I
Cat.No: T83668
Synonym: NucGel Green I Nucleic Acid Gel Stain,Green I Nucleic Acid Gel Stain
Target:
CelGreen nucleic acid gel stain *10,000× concentrate in DMSO*
Cat.No: TD0003L
Synonym:
Target:
DMGF
Cat.No: T69269
Synonym:
Target:
CelGreen nucleic acid gel stain *10,000× concentrate in water*
Cat.No: TD0003
Synonym:
Target: Others
2'-Deoxyadenosine-5'-triphosphate (sodium salt hydrate)
Cat.No: T37106
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T38427 dUTP trisodium

2'-Deoxyuridine-5'-triphosphate trisodium salt,Deoxyuridine triphosphate

DNA/RNA Synthesis Cell Cycle/Checkpoint; DNA Damage/DNA Repair
dUTP trisodium (Deoxyuridine triphosphate) 是在 5'-位具有三磷酸基团的脱氧尿苷磷酸盐,可用于 PCR
T7520 Deoxycytidine triphosphate

Nucleoside Antimetabolite/Analog; DNA/RNA Synthesis; Endogenous Metabolite Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
Deoxycytidine triphosphate 是一种核苷三磷酸,是合成 DNA 的原料,可用于实时荧光定量 PCR、cDNA 合成和 DNA 测序。
T4883 Creatine

Methylguanidoacetic acid,肌酸

Endogenous Metabolite Metabolism
Creatine (Methylguanidoacetic acid) 是一种内源性氨基酸代谢物,在细胞能量中发挥重要作用,尤其是在肌肉和大脑中。

天然产物

dUTP trisodium
Cat.No: T38427
Synonym: 2'-Deoxyuridine-5'-triphosphate trisodium salt,Deoxyuridine triphosphate
Target: DNA/RNA Synthesis
Deoxycytidine triphosphate
Cat.No: T7520
Synonym:
Target: Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis, Endogenous Metabolite
Creatine
Cat.No: T4883
Synonym: Methylguanidoacetic acid,肌酸
Target: Endogenous Metabolite
TargetMol Loading
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