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Cat. No.	Product Name	Target	Signaling Pathways
TP1369L	[Sar9,Met(O2)11]-Substance P acetate [Sar9,Met(O2)11]-Substance P acetate(110880-55-2 free base)	Neurokinin receptor	GPCR/G Protein; Neuroscience
	[Sar9,Met(O2)11]-Substance P acetate(110880-55-2 free base) 是一种速激肽 NK1 受体选择性激动剂。它是一种选择性速激肽 NK1 受体激动剂。它和 septide（每只大鼠 10-100 pmol，i.c.v.）在增加平均动脉血压 (MAP) 和心率 (HR)，但它们的时间进程不同。两种激动剂都以剂量依赖性方式增加洗脸和吸鼻，而它是一种产生美容效果的化合物。
T7828	[Sar9,Met(O2)11]-Substance P Bhsar-sp,NA,精氨酰-脯氨酰-赖氨酰-脯氨酰-谷氨酰-谷氨酰-苯丙氨酰-苯丙氨酰-SAR-亮氨酸-蛋氨酸[O2]-胺	Neurokinin receptor	GPCR/G Protein; Neuroscience
	[Sar9,Met(O2)11]-Substance P (NA) 是选择性速激肽NK1受体激动剂。
TP1369	[Sar9,Met(O2)11]-Substance P TFA(110880-55-2,free) [Sar9,Met(O2)11]-Substance P TFA
	[Sar9,Met(O2)11]-Substance P TFA is a selective tachykinin NK1 receptor agonist.[Sar9,Met(O2)11]-Substance P and septide (10-100 pmol per rat, i.c.v.) are equipotent in increasing mean arterial blood pressure (MAP) and heart rate (HR), yet they have dissi
T9052	XL092 CL-092,JUN04542	VEGFR; c-Met/HGFR; TAM Receptor	Angiogenesis; Tyrosine Kinase/Adaptors
	XL092 (JUN04542) 是一种ATP 竞争性的、口服有效的多受体酪氨酸激酶 (RTKs) 抑制剂，在细胞分析中的MET (IC50:15 nM)、VEGFR2 (IC50:1.6 nM)、AXL (IC50:3.4 nM) 和 MER (IC50:7.2 nM)。它具有抗肿瘤作用，具有用于研究激酶依赖性疾病的潜力。
T25098	Antiflammin P2 Hdmnkvldl,Antiflamin 2,His-asp-met-asn-lys-val-leu-asp-leu
	Antiflammin P2 is a nonapeptide fragment of lipocortin I which has no phospholipase A2 inhibitory and anti-inflammatory activity.
T75769	[Sar9,Met(O2)11]-Substance P TFA
	[Sar9,Met(O2)11]-Substance P TFA 是一种选择性的速激肽NK1受体激动剂。
TQ0210	Savolitinib AZD-6094,Volitinib,沃利替尼,赛沃替尼,HMPL-504	c-Met/HGFR	Tyrosine Kinase/Adaptors
	Savolitinib (Volitinib) 是一种高效选择性、口服生物利用度c-Met 抑制剂，能够抑制 c-Met (IC50:5 nM)和 p-Met (IC50:3 nM)。它以 ATP 竞争的方式选择性结合并抑制 c-Met 的激活，破坏 c-Met 信号转导途径，具有抗肿瘤作用。
T77575	P-gb-IN-1	P-gp	Membrane transporter/Ion channel; Neuroscience
	P-gb-IN-1 是一种有效的 P-糖蛋白 (P-gp) 抑制剂，通过抑制 P-gp 外流展现出逆转活性。P-gb-IN-1 通过与残基 Asn 721 和 Met 986 形成氢键相互作用从而显示出对 P-gp 的抑制作用。P-gb-IN-1 在 MCF-7/ADR 细胞中显示出低毒性。
TP1862L	[Sar9] Substance P acetate(77128-75-7 free base)	Neurokinin receptor	GPCR/G Protein; Neuroscience
	[Sar9] Substance P acetate(77128-75-7 free base) 是一种 NK-1 受体激动剂。 rNK1 特异性激动剂 [Sar-9,Met(O2)11]-SP 模拟了 SP 对孕酮代谢的作用。
T76452	Gly-Leu-Met-NH2
	Gly-Leu-Met-NH2 是 Substance P (Substance P ) 的 C 端三肽。Substance P 是一种神经肽。
T15384	Glesatinib MGCD265	c-Met/HGFR	Tyrosine Kinase/Adaptors
	Glesatinib is an orally active and potent dual inhibitor of MET/SMO. Glesatinib is also a tyrosine kinase inhibitor. It antagonizes P-glycoprotein mediated multidrug resistance (MDR) in NSCLC.
T76449	Substance P (alligator)
	Substance P (alligator)，一种从鳄鱼中提取的神经肽，其氨基酸序列为Arg-Pro-Arg-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2。
T15383	Glesatinib hydrochloride MGCD265 hydrochloride	c-Met/HGFR	Tyrosine Kinase/Adaptors
	Glesatinib hydrochloride is an orally active and potent dual inhibitor of MET/SMO. Glesatinib hydrochloride is also a tyrosine kinase inhibitor. It antagonizes P-glycoprotein mediated multidrug resistance (MDR) in NSCLC.
T70456	Nolpitantium Free Base
	Nolpitantium Free Base is a highly selective nonpeptide antagonist of neurokinin-1 (NK1) receptor. Nolpitantium potently, selectively and competitively inhibited substance P binding to NK1 receptors from various animal species, including humans. In vitro, it was a potent antagonist in functional assays for NK1 receptors such as [Sar9, Met(O2)11]substance P-induced endothelium-dependent relaxation of rabbit pulmonary artery and contraction of guinea-pig ileum. Up to 1 mkM, Nolpitantium had no eff...
TP1862	[Sar9] Substance P
	[Sar9]-Substance P is one of NK-1 receptor agonist. The action of SP on progesterone metabolism was mimicked by the rNK1-specific agonist [Sar-9,Met(O2)11]-SP.
T29186	YM49598 YM-49598,YM 49598
	YM49598 is a tachykinin receptor antagonist. YM49598 exhibited high binding affinities at NK(1) (pK(i) = 9.09 +/- 0.02) and NK(2) (pK(i) = 9.94 +/- 0.03) receptors, respectively. YM49598 was almost inactive but produced a potent inhibition (IC(50) = 11 +/

化合物

[Sar9,Met(O2)11]-Substance P acetate

Cat.No: TP1369L

Synonym: [Sar9,Met(O2)11]-Substance P acetate(110880-55-2 free base)

Target: Neurokinin receptor

[Sar9,Met(O2)11]-Substance P

Cat.No: T7828

Synonym: Bhsar-sp,NA,精氨酰-脯氨酰-赖氨酰-脯氨酰-谷氨酰-谷氨酰-苯丙氨酰-苯丙氨酰-SAR-亮氨酸-蛋氨酸[O2]-胺

Target: Neurokinin receptor

[Sar9,Met(O2)11]-Substance P TFA(110880-55-2,free)

Cat.No: TP1369

Synonym: [Sar9,Met(O2)11]-Substance P TFA

Cat.No: T9052

Synonym: CL-092,JUN04542

Target: VEGFR, c-Met/HGFR, TAM Receptor

Cat.No: T25098

Synonym: Hdmnkvldl,Antiflamin 2,His-asp-met-asn-lys-val-leu-asp-leu

[Sar9,Met(O2)11]-Substance P TFA

Cat.No: T75769

Cat.No: TQ0210

Synonym: AZD-6094,Volitinib,沃利替尼,赛沃替尼,HMPL-504

Target: c-Met/HGFR

Cat.No: T77575

Target: P-gp

[Sar9] Substance P acetate(77128-75-7 free base)

Cat.No: TP1862L

Target: Neurokinin receptor

Gly-Leu-Met-NH2

Cat.No: T76452

Cat.No: T15384

Synonym: MGCD265

Target: c-Met/HGFR

Substance P (alligator)

Cat.No: T76449

Glesatinib hydrochloride

Cat.No: T15383

Synonym: MGCD265 hydrochloride

Target: c-Met/HGFR

Nolpitantium Free Base

Cat.No: T70456

[Sar9] Substance P

Cat.No: TP1862

Cat.No: T29186

Synonym: YM-49598,YM 49598

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