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Cat. No. | Product Name | Target | Signaling Pathways |
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T6073 |
OG-L002
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Histone Demethylase; Monoamine Oxidase; HSV | Chromatin/Epigenetic; Microbiology/Virology; Neuroscience |
OG-L002 是一种高度选择性的 LSD1有效抑制剂,IC50为 0.02 μM。它抑制HSV IE 基因的表达,还是单胺氧化酶抑制剂,对 MAO-A 和 MAO-B 的IC50分别为 1.38 μM 和 0.72 μM。 | |||
T77615 |
ND-011992
ND011992 |
Mitochondrial Metabolism; Antibacterial | Metabolism; Microbiology/Virology |
ND-011992 是一种靶向醌还原酶 (quinone reductases) 和醌氧化酶 (quinol oxidases)的喹唑啉类抑制剂,具有可逆性和选择性。ND-011992 对大肠杆菌 BL21*Δcyo 呼吸复合体I (respiratory complex I) 、 bo3 氧化酶(bo3 oxidase)、 bd-I 氧化酶 (bd-I oxidases) 和 bd-II 氧化酶 (bd-II oxidases)具有抑制作用,IC50 分别为 0.12、2.47、0.63 和 1.3 μM。ND-011992 可以用于研究肺结核。 | |||
T7575L1 |
[Sar1, Ile8]-Angiotensin II acetate
|
RAAS | Endocrinology/Hormones |
[Sar1, Ile8]-Angiotensin II acetate 可激活 NADPH 和 NADH 氧化酶,并刺激血管平滑肌细胞中超氧阴离子的形成。 [Sar1, Ile8]-Angiotensin II acetate 对血管平滑肌有多种作用,包括正常动脉的收缩和培养细胞或病变血管的肥大或增生。 | |||
T7433 |
2-Phenylethylamine hydrochloride
&beta,-Phenylethylamine hydrochloride,2-苯乙胺盐酸盐,benzeneethanamine hydrochloride,&beta,-aminoethylbenzene hydrochloride |
Others | Others |
2-Phenylethylamine hydrochloride (benzeneethanamine hydrochloride) 是神经调节剂或神经递质。 | |||
T38966 |
PXS-4681A
|
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PXS-4681A is a powerful, specific, and irreversible inhibitor of semicarbazide-sensitive amine oxidase (SSAO; VAP-1), with an oral activity and a Ki value of 37 nM. It exhibits exceptional selectivity towards related amine oxidases, ion channels, and seven-transmembrane domain receptors. Additionally, PXS-4681A demonstrates potent anti-inflammatory properties. | |||
T70163 | Bizine dihydrochloride | ||
Bizine dihydrochloride is a potent LSD1 inhibitor in vitro, being selective versus monoamine oxidases A/B and the LSD1 homologue, LSD2. | |||
T35625 |
Aminoacetone (hydrochloride)
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Aminoacetone is a threonine and glycine catabolite that can be converted to methylglyoxal by amine oxidases. It has been identified as one of several endogenous sources of methylglyoxal found in the plasma of diabetes patients. As a pro-oxidant, 0.10-5 mM aminoacetone can induce cell death in RINm5f pancreatic β-cells. Aminoacetone is used as a growth substrate for Pseudomonas. | |||
T37092 |
20-HEPE
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20-HEPE is a metabolite of eicosapentaenoic acid that is formed via ω-oxidation of EPA by cytochrome P450 (CYP) ω-oxidases, including human CYP4F3B. It activates peroxisome proliferator-activated receptor α (PPARα) in COS-7 cells expressing a luciferase reporter when used at a concentration of 10 μM. 20-HEPE also activates murine transient receptor potential vanilloid receptor 1 (mTRPV1) in vitro but lacks antinociceptive activity in rats. |
Cat. No. | Product Name | Target | Signaling Pathways |
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T3822 |
Bellidifolin
Bellidifoline,龙胆山酮酚,Bellidifolium,雏菊叶龙胆酮 |
Others; HIV Protease | Microbiology/Virology; Others; Proteases/Proteasome |
Bellidifolin (Bellidifoline) 是从獐牙菜的茎中提取的一种呫吨酮,它能作为病毒蛋白 R 的抑制剂,具有保肝、降血糖、抗炎、抗氧化、抗肿瘤作用。 |