Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T9223 |
RO-0335
|
Reverse Transcriptase | Microbiology/Virology |
RO-0335 是新高效二苯醚非核苷逆转录酶抑制剂。它 (IC50= 1.1 nM) 可以抑制Wt HIV-1病毒,对 92% 的 NNRTI 耐药临床分离株具有保留活性 (IC50<100 nM)。 | |||
TQ0122L |
VCH-916 free acid(1200133-34-1 free base)
|
HCV Protease | Microbiology/Virology; Proteases/Proteasome |
VCH-916 free acid(1200133-34-1 free base) 是一种新型非核苷 HCV NS5B 聚合酶抑制剂。 | |||
T27260 |
Emivirine
MKC442,MKC-442,MKC 442,DRG-0302,DRG 0302,DRG0302 |
HIV Protease | Microbiology/Virology; Proteases/Proteasome |
Emivirine (MKC-442) 是一种有效和选择性的人类免疫缺陷病毒1型(HIV-1)的非核苷逆转录酶抑制剂。 | |||
T12715 |
Reverse transcriptase-IN-1
|
HIV Protease | Microbiology/Virology; Proteases/Proteasome |
Reverse transcriptase-IN-1 是一种二芳基苯并嘧啶类似物,是一种有效的 HIV-1 非核苷类逆转录酶抑制剂,IC50 为 13.7 nM。 | |||
T8800 |
NSAH
2-hydroxy-N'-[(E)-(2-hydroxynaphthalen-1-yl)methylidene]benzohydrazide |
DNA/RNA Synthesis | Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
NSAH (2-hydroxy-N'-[(E)-(2-hydroxynaphthalen-1-yl)methylidene]benzohydrazide) 是一种可逆竞争性非核苷类的核苷酸还原酶抑制剂,无细胞 IC50 为 32 μM,基于细胞的 IC50 约为 250 nM。 | |||
T25363 |
Efavirenz, (R)-
L 743725,L-743725,L743725 |
||
Efavirenz, (R)- is an antiviral agent and a nonnucleoside HIV-1 reverse transcriptase inhibitor. | |||
TQ0122 |
VCH-916
|
HCV Protease | Microbiology/Virology; Proteases/Proteasome |
VCH-916 是一种新型非核苷类 HCV NS5B 聚合酶抑制剂。 | |||
T14086 |
ABT-072
|
Others | Others |
ABT-072 is a nonnucleoside NS5B polymerase inhibitor and a candidate drug evaluated for treatment of hepatitis C virus. | |||
T26442 |
A 75925
A-75925,A75925 |
||
A 75925, a nonnucleoside reverse transcriptase inhibitors (NNRTI), works to inhibit HIV-1 replication. | |||
T24794 |
SJ-3366
SJ 3366 |
||
SJ3366 is a unique and highly potent nonnucleoside reverse transcriptase human immunodeficiency virus type 1 and HIV-2 inhibitor. | |||
T70212 | U 95133 | ||
U 95133 is a potent, broad-spectrum nonnucleoside reverse transcriptase inhibitor of drug-resistant isolates of human immunodeficiency virus type 1. | |||
T31085 |
CP-94707
UNII-YGC6408B5O |
||
CP-94707 is a new inhibitor of nonnucleoside reverse transcriptase (NNRTI). | |||
T27442 |
GSK 224876
GSK-224876,GSK224876 |
||
GSK 224876 is a novel next-generation nonnucleoside reverse transcriptase inhibitor (NNRTI). It has activity against efavirenz-resistant strains in the treatment of treatment-naive HIV-1-infected subjects. | |||
T30185 |
AT 61
AT61,AT-61 |
||
AT-61 is a nonnucleoside analogue inhibitor of hepatitis B virus (HBV) replication. | |||
T16081 |
MIV-150
PC 815 |
Others | Others |
MIV-150 is a nonnucleoside inhibitor of reverse transcriptase (NNRT). MIV-150 also blocking HIV-1 and HIV-2 infections (EC50<1 nM against HIV-1/HIV-2MN). | |||
T78167 |
PYR01
|
||
PYR01为一种高效的HIV-1非核苷逆转录酶抑制剂,同时作为针对消除表达HIV-1细胞的细胞杀伤分子的靶向激活剂。 | |||
T72283 |
(+)-Dihydrocalanolide A
NSC 678323,DHCal A ; NSC 678323,DHCal A |
||
(+)-Dihydrocalanolide A (DHCal A ; NSC 678323) 是一种口服有效、非核苷的逆转录酶 (Reverse Transcriptase) 抑制剂。(+)-Dihydrocalanolide A 可用于 HIV |