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39

抑制剂 & 化合物

1

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Cat. No.	Product Name	Target	Signaling Pathways
TP1341L	Polymyxin B nonapeptide acetate Polymyxin B nonapeptide acetate(86408-36-8 free base)	Antibacterial; Antibiotic	Microbiology/Virology
	Polymyxin B nonapeptide acetate(86408-36-8 free base) 是一种阳离子环肽。 Polyxin B 九肽是 polyxin B 经酶解产生的衍生物。与 polyxin B 相比，polyxin B 九肽毒性低，缺乏杀菌活性，仍具有破坏革兰氏阴性菌外膜的能力。
TP1101	Nonapeptide-1 acetate salt (158563-45-2 free base) Melanostatine-5 acetate salt,Nonapeptide-1 acetate salt	Melanocortin Receptor	GPCR/G Protein; Neuroscience
	Nonapeptide-1 acetate salt (158563-45-2 free base) (Melanostatine-5 acetate salt) 是一种肽激素，是一种有效的 α-黑色素细胞刺激素 (α-MSH) 拮抗剂，IC50 为 11 nM。
T7769	Nonapeptide-1 Met-Pro-D-Phe-Arg-D-Trp-Phe-Lys-Pro-Val-,九胜肽-1,Melanostatine™ 5	Others	Others
	Nonapeptide-1 (Melanostatine™ 5) 可以抑制黑色素的合成，这使得它对治疗某些皮肤病很感兴趣。
TP2419	V-9-M Cholecystokinin nonapeptide V 9 M,Prepro CCK Fragment V-9-M,Val-pro-val-glu-ala-val-asp-pro-met,Cholecystokinin Precursor (24-32),V9M,V-9-M	Beta Amyloid	Neuroscience
	V-9-M Cholecystokinin nonapeptide (Prepro CCK Fragment V-9-M) 是胆囊收缩素(CCK)的前体化合物。胆囊收缩素(CCK)是一种刺激胆囊收缩和胰腺外分泌的脑肠肽，可从狗和猫的小肠中提取的，可以引起胆囊收缩。
TP1341	Polymyxin B nonapeptide
	Polymyxin B nonapeptide, a cationic cyclic peptide derived by enzymatic processing from the naturally occurring peptide polymyxin B, is able to increase the permeability of the outer membrane of Gram-negative bacteria toward hydrophobic antibiotics probab
TP2409	SP-346 nonapeptide H-Val-Ser-Gln-Asn-Tyr-Pip-Ile-Val-Gln-NH2
	SP-346 nonapeptide is a pipecolic acid substituted nonapeptide.
T32139	Igercine Ige C-terminal nonapeptide
	Igercine is the C-terminal nonapeptide in immunoglobulin E.
T64687	Polymyxin B nonapeptide TFA
	Polymyxin B nonapeptide TFA 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T64687。
T75715	Nonapeptide-1 acetate salt
	Nonapeptide-1 (Melanostatine-5) acetate salt，一种多肽类激素，是 MC1R 选择性拮抗剂 (Ki: 40 nM)。 Nonapeptide-1 acetate salt 是一种竞争性的α-MSH 拮抗剂，可有效抑制黑素细胞中 α-MSH 诱导的细胞内 cAMP 和黑素体扩散 (IC50分别为 2.5 nM 和 11 nM)。 Nonapeptide-1 acetate salt 抑制黑色素合成，可用于研究皮肤色素沉着和肾上腺类固醇生成的调节、皮肤癌。
T4996	Atosiban 阿托西班,RWJ22164,RW22164	Oxytocin Receptor; Vasopressin Receptor	Endocrinology/Hormones; GPCR/G Protein
	Atosiban (RW22164) 是一种脱氨基催产素类似物，是一种九肽，也是竞争性的催产素受体拮抗剂。它是一种宫缩抑制剂，可用于自发早产的研究。
T5148	Atosiban acetate RW22164,Atosiban acetate (90779-69-4 free base),RWJ22164,醋酸阿托西班	Oxytocin Receptor; Vasopressin Receptor	Endocrinology/Hormones; GPCR/G Protein
	Atosiban acetate (RW22164) 是一种脱氨基催产素类似物，是一种九肽，也是竞争性的催产素受体拮抗剂。它是一种宫缩抑制剂，可用于自发早产的研究。
TP1819L	Substance P 1-9 aceate	Neurotensin Receptor	GPCR/G Protein
	Substance P 1-9 aceate 是九肽，可减少豚鼠回肠和膀胱对 P 物质的失活。
TP1496L	p5 Ligand for Dnak and DnaJ acetate p5 Ligand for Dnak and DnaJ acetate(209518-24-1 free base)	HSP	Cytoskeletal Signaling; Metabolism
	p5 Ligand for Dnak and DnaJ acetate(209518-24-1 free base) 是一种九肽。它是 DnaK（大肠杆菌 Hsp70）和 DnaJ（大肠杆菌 Hsp40）的高亲和力配体。
T9857L	Vasopressin acetate Vasopressin acetate (11000-17-2 Free base)	Endogenous Metabolite	Metabolism
	Vasopressin acetate 是一种环状九肽，在下丘脑中枢合成。 Vasopressin acetate 作为一种神经递质，通过与特定的 G 蛋白偶联受体结合发挥其作用。
TP1617L	Chemerin-9 (149-157) acetate Chemerin-9 (149-157) acetate (676367-27-4 free base)	Others	Others
	Chemerin-9 (149-157) acetate (676367-27-4 free base) 对应于加工的 chemerin 的 C 末端，保留了全尺寸蛋白质的大部分活性和关于对 chemerinR 的激动。它是 ChemR23 (chemerinR) 的天然配体。
TP1900L1	Hemopressin (human, mouse) acetate Hemopressin (human, mouse) acetate(1314035-51-2 free base)	Cannabinoid Receptor	GPCR/G Protein
	Hemopressin (human, mouse) acetate(1314035-51-2 free base) 是一种衍生自血红蛋白 α1 链的九肽，是从大鼠脑匀浆中分离出来的。 Hemopressin 是 CB1 大麻素受体的口服活性、选择性和反向激动剂。 Hemopressin 在炎性疼痛模型中发挥镇痛作用。
TP1901L1	Hemopressin (rat) acetate(568588-77-2 free base)	Cannabinoid Receptor	GPCR/G Protein
	Hemopressin (rat) acetate(568588-77-2 free base) 是一种衍生自血红蛋白 α1 链的九肽，起初是从大鼠脑匀浆中分离出来的。 Hemopressin 是 CB2 大麻素受体的口服活性、选择性和反向激动剂。 Hemopressin 在炎性疼痛模型中发挥镇痛作用。
TP2107L	Histrelin acetate Histrelin acetate(76712-82-8 free base),醋酸组氨瑞林	GNRH Receptor	GPCR/G Protein
	Histrelin acetate 是促性腺激素释放激素 (GnRH) 的九肽类似物，具有增加的效力。当存在于血流中时，它作用于称为促性腺激素的垂体特定细胞。 Histrelin 刺激这些细胞释放促黄体激素和促卵泡激素。因此，它被认为是促性腺激素释放激素激动剂或 GnRH 激动剂。
T37664	Emideltide (acetate)
	Emideltide, also known as delta sleep-inducing peptide (DSIP), is a synthetic nonapeptide sedative.1
TP2377	Cyclolinopeptide A Linus cyclopeptide 9
	Cyclolinopeptide A is a cyclic nonapeptide extracted from linseed oil.
T25098	Antiflammin P2 Hdmnkvldl,Antiflamin 2,His-asp-met-asn-lys-val-leu-asp-leu
	Antiflammin P2 is a nonapeptide fragment of lipocortin I which has no phospholipase A2 inhibitory and anti-inflammatory activity.
T37795	Retrobradykinin
	Bradykinin analog nonapeptide. Reverse sequence of Bradykinin (Cat.No. 3004). Exhibits no significant kinin activity. Can be used as a negative control. Lande (1962) Retrobradykinin: a peptide with the reverse sequence of bradykinin. J.Org.Chem. 27 4558
T80962	TPNQRQNVC LRH-1 peptide
	TPNQRQNVC为HLA-B0702的九肽抗原决定簇，能激活CD8+ T细胞的免疫响应。
T80540	TCMCB07	Melanocortin Receptor	GPCR/G Protein; Neuroscience
	TCMCB07为环状九肽，是具有口服活性及脑渗透性的黑皮质素受体4 (MC4R) 拮抗剂，在恶病质中具有关键作用。
TP2156L	TAK-683	Others	Others
	TAK-683 is an effective full KISS1 receptor agonist (IC50=170 pM). TAK-683 is a nonapeptide metastin analog, shows agonistic activities to KISS1R (EC50: 0.96 nM and 1.6 nM for human and rat, respectively).
TP1435	Chemerin-9 (149-157) TFA(676367-27-4 free base) Chemerin-9 (149-157) (TFA)
	Chemerin-9 (149-157) TFA, the nonapeptide (149)YFPGQFAFS(157) (chemerin-9), corresponding to the C terminus of processed chemerin, retains most of the activity of the full-size protein, with regard to agonism toward the chemerinR[1].
T37890	GLP-1(28-36)amide
	GLP-1(28-36)amide, a C-terminal nonapeptide derived from the cleavage of GLP-1 by neutral endopeptidase (NEP), is a significant product. It functions as an antioxidant and primarily targets the mitochondrion, where it effectively inhibits mitochondrial permeability transition (MPT). This compound exhibits anti-diabetic properties and demonstrates cardioprotection effects[1].
TP1819	Substance P (1-9)
	Substance P (1-9) is nonapeptide, which decreases the inactivation of substance P by the guinea-pig ileum and urinary bladder. Subtance P is responsible for a number of excitatory effects on both central and peripheral neurons.
TP1617	Chemerin-9 (149-157) Chemerin-9 149-157
	The nonapeptide 149,YFPGQFAFS157 (chemerin-9), corresponding to the C terminus of processed chemerin, retained most of the activity of the full-size protein, with regard to agonism toward the chemerinR.the natural ligand of ChemR23 (chemerinR).
T80911	Tyrosinase (192-200), human mouse
	Tyrosinase(192-200), human mouse 为九肽化合物，能被HLA-B44分子所识别的细胞溶解T细胞（CTL）所识别，常用于黑色素瘤相关癌症研究。
TP1413	Crustacean Cardioactive Peptide (CCAP) Crustacean Cardioactive Peptide CCAP,甲壳类心脏活性肽
	Crustacean cardioactive peptide (CCAP) is a highly conserved, amidated cyclic nonapeptide with the primary structure PFCNAFTGC-NH2 (ProPheCysAsnAlaPheTyrGlyCys-NH2) and a disulfide bridge between Cys3 and Cys9. It is found in crustaceans and insects where
T80541	TCMCB07 TFA	Melanocortin Receptor	GPCR/G Protein; Neuroscience
	TCMCB07 TFA为一环状九肽，属口服活性及脑渗透性黑皮质素受体4 (MC4R) 拮抗剂，于恶病质中扮演关键角色。
T76550	CooP
	CooP为一种针对线性胶质母细胞瘤的九肽，与胶质母细胞瘤细胞及其相关血管系统中的乳腺来源生长抑制剂/脂肪酸结合蛋白3 (FABP3) 发生结合。该化合物主要应用于化学疗法和多种纳米粒子的靶向递送。
T75799	Hemopressin(human, mouse) TFA	Cannabinoid Receptor	GPCR/G Protein
	Hemopressin TFA，一种衍生自血红蛋白α1链的九肽，最初自大鼠脑匀浆分离。作为口服活性且选择性的CB1大麻素受体反向激动剂，Hemopressin TFA在炎性疼痛模型中具有抗伤害感受效应。
T76191	GLP-1(28-36)amide TFA
	GLP-1(28-36)amide TFA，为GLP-1 C-端九肽段，主要通过中性内肽酶（NEP）裂解GLP-1生成。该化合物作为一种抗氧化剂，能靶向线粒体，抑制线粒体通透性转变（MPT），显示出抗糖尿病和心脏保护的功效。
T21308	Histrelin Supprelin LA,组氨瑞林,Histrelin Acetate	Others	Others
	Histrelin (Supprelin LA) 是促性腺激素释放激素 (GnRH) 的九肽类似物，具有增加的效力。它被认为是 GnRH 激动剂。 Histrelin 用于治疗对激素敏感的男性前列腺癌和女性子宫肌瘤。
T75798	Hemopressin(rat) TFA
	Hemopressin(rat) TFA，一种衍生自α1-珠蛋白九肽，最初分离自大鼠脑匀浆。该化合物通过口服能有效选择性地作为CB1大麻素受体的反向激动剂，并在炎性疼痛模型中表现出抗伤害感受活性。
T76048	TAK-683 acetate
	TAK-683 acetate是一种高效的KISS1R激动剂(IC50=170 pM)，改善了代谢稳定性。作为九肽metastin的类似物，对人和大鼠的EC50值分别为0.96 nM和1.6 nM。该化合物通过消耗下丘脑GnRH，能够降低血浆FSH、LH、睾酮水平，展示了对研究激素依赖性前列腺癌的潜力。
T76047	TAK-683 TFA
	TAK-683 TFA是一种高效的全KISS1R激动剂(IC50=170 pM)，拥有较好的代谢稳定性，是九肽metastin的类似物，对KISS1R有激动效应，其对人和大鼠EC50值分别为0.96 nM和1.6 nM。TAK-683 TFA能够降低下丘脑GnRH水平，进而减少血浆FSH、LH、睾酮的浓度，显示出对激素依赖性前列腺癌研究的可能性。

化合物

Polymyxin B nonapeptide acetate

Cat.No: TP1341L

Synonym: Polymyxin B nonapeptide acetate(86408-36-8 free base)

Target: Antibacterial, Antibiotic

Nonapeptide-1 acetate salt (158563-45-2 free base)

Cat.No: TP1101

Synonym: Melanostatine-5 acetate salt,Nonapeptide-1 acetate salt

Target: Melanocortin Receptor

Nonapeptide-1

Cat.No: T7769

Synonym: Met-Pro-D-Phe-Arg-D-Trp-Phe-Lys-Pro-Val-,九胜肽-1,Melanostatine™ 5

Target: Others

V-9-M Cholecystokinin nonapeptide

Cat.No: TP2419

Synonym: V 9 M,Prepro CCK Fragment V-9-M,Val-pro-val-glu-ala-val-asp-pro-met,Cholecystokinin Precursor (24-32),V9M,V-9-M

Target: Beta Amyloid

Polymyxin B nonapeptide

Cat.No: TP1341

SP-346 nonapeptide

Cat.No: TP2409

Synonym: H-Val-Ser-Gln-Asn-Tyr-Pip-Ile-Val-Gln-NH2

Cat.No: T32139

Synonym: Ige C-terminal nonapeptide

Polymyxin B nonapeptide TFA

Cat.No: T64687

Nonapeptide-1 acetate salt

Cat.No: T75715

Cat.No: T4996

Synonym: 阿托西班,RWJ22164,RW22164

Target: Oxytocin Receptor, Vasopressin Receptor

Atosiban acetate

Cat.No: T5148

Synonym: RW22164,Atosiban acetate (90779-69-4 free base),RWJ22164,醋酸阿托西班

Target: Oxytocin Receptor, Vasopressin Receptor

Substance P 1-9 aceate

Cat.No: TP1819L

Target: Neurotensin Receptor

p5 Ligand for Dnak and DnaJ acetate

Cat.No: TP1496L

Synonym: p5 Ligand for Dnak and DnaJ acetate(209518-24-1 free base)

Target: HSP

Vasopressin acetate

Cat.No: T9857L

Synonym: Vasopressin acetate (11000-17-2 Free base)

Target: Endogenous Metabolite

Chemerin-9 (149-157) acetate

Cat.No: TP1617L

Synonym: Chemerin-9 (149-157) acetate (676367-27-4 free base)

Target: Others

Hemopressin (human, mouse) acetate

Cat.No: TP1900L1

Synonym: Hemopressin (human, mouse) acetate(1314035-51-2 free base)

Target: Cannabinoid Receptor

Hemopressin (rat) acetate(568588-77-2 free base)

Cat.No: TP1901L1

Target: Cannabinoid Receptor

Histrelin acetate

Cat.No: TP2107L

Synonym: Histrelin acetate(76712-82-8 free base),醋酸组氨瑞林

Target: GNRH Receptor

Emideltide (acetate)

Cat.No: T37664

Cyclolinopeptide A

Cat.No: TP2377

Synonym: Linus cyclopeptide 9

Cat.No: T25098

Synonym: Hdmnkvldl,Antiflamin 2,His-asp-met-asn-lys-val-leu-asp-leu

Retrobradykinin

Cat.No: T37795

Cat.No: T80962

Synonym: LRH-1 peptide

Cat.No: T80540

Target: Melanocortin Receptor

Cat.No: TP2156L

Target: Others

Chemerin-9 (149-157) TFA(676367-27-4 free base)

Cat.No: TP1435

Synonym: Chemerin-9 (149-157) (TFA)

GLP-1(28-36)amide

Cat.No: T37890

Substance P (1-9)

Cat.No: TP1819

Chemerin-9 (149-157)

Cat.No: TP1617

Synonym: Chemerin-9 149-157

Tyrosinase (192-200), human mouse

Cat.No: T80911

Crustacean Cardioactive Peptide (CCAP)

Cat.No: TP1413

Synonym: Crustacean Cardioactive Peptide CCAP,甲壳类心脏活性肽

Cat.No: T80541

Target: Melanocortin Receptor

Cat.No: T76550

Hemopressin(human, mouse) TFA

Cat.No: T75799

Target: Cannabinoid Receptor

GLP-1(28-36)amide TFA

Cat.No: T76191

Cat.No: T21308

Synonym: Supprelin LA,组氨瑞林,Histrelin Acetate

Target: Others

Hemopressin(rat) TFA

Cat.No: T75798

TAK-683 acetate

Cat.No: T76048

Cat.No: T76047

Cat. No.	Product Name	Target	Signaling Pathways
T73954	Leucinostatin (mixture of A&B)
	Leucinostatin (mixture of A&B) 是来自Paecilomyces lilacinus 的九肽类复合物，具有抗生素活性。

天然产物

Leucinostatin (mixture of A&B)

Cat.No: T73954

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