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Cat. No. Product Name Target Signaling Pathways
T4246 Varenicline dihydrochloride

AChR Neuroscience
Varenicline dihydrochloride是一种选择性 α4β2 烟碱乙酰胆碱受体部分激动剂。
T10432L AZD-8529 mesylate

GluR Neuroscience
AZD-8529 mesylate 是高度选择性的可口服mGluR2正向调节剂,EC50值为 285 nM。它在 20-25 M 时,对 mGluR1、3、4、5、6、7 和 8 亚型没有显示正变构调节剂反应。
T61562 CB1R Allosteric modulator 3

cAMP; Cannabinoid Receptor GPCR/G Protein
CB1R Allosteric modulator 3 是一种有效的 CB1R 调制剂。CB1R Allosteric modulator 3 抑制 cAMP 和 β-Arrestin ,可用于研究肥胖和尼古丁成瘾。
T16563 Pozanicline

ABT-089

AChR Neuroscience
Pozanicline reverses nicotine withdrawal-induced cognitive deficits, may be an effective component of novel therapeutic strategies for nicotine addiction. Pozanicline selectively activate neuronal nicotinic acetylcholine receptor (nAChR) subtypes, is a no
T38903 (S)-UFR2709

(S)-UFR2709

(S)-UFR2709 is a competitive antagonist of the nicotinic acetylcholine receptor (nAChR), exhibiting a greater affinity for α4β2 nAChRs compared to α7 nAChRs. It effectively reduces anxiety and ethanol consumption, as well as ethanol preference, in alcohol-preferring rats. Additionally, (S)-UFR2709 functions as an anxiolytic agent and holds the potential for investigating nicotine addiction.
T37094 (S)-UFR2709 hydrochloride

(S)-UFR2709 hydrochloride

(S)-UFR2709 (hydrochloride) is a competitive nAChR antagonist and displays higher affinity for α4β2 nAChRs than for α7 nAChRs. (S)-UFR2709 (hydrochloride) decreases anxiety and reduces ethanol consumption and ethanol preference in alcohol-preferring rats. (S)-UFR2709 (hydrochloride) acts as an anxiolytic agent and can be used for the study of nicotine addiction[1][2]. Brain nicotinic acetylcholine receptors (nAChRs) is a heterogeneous family of pentameric acetylcholine-gated cation channels, whi...

化合物

Varenicline dihydrochloride
Cat.No: T4246
Synonym:
Target: AChR
AZD-8529 mesylate
Cat.No: T10432L
Synonym:
Target: GluR
CB1R Allosteric modulator 3
Cat.No: T61562
Synonym:
Target: cAMP, Cannabinoid Receptor
Pozanicline
Cat.No: T16563
Synonym: ABT-089
Target: AChR
(S)-UFR2709
Cat.No: T38903
Synonym: (S)-UFR2709
Target:
(S)-UFR2709 hydrochloride
Cat.No: T37094
Synonym: (S)-UFR2709 hydrochloride
Target:
TargetMol Loading
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