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Search Results for " neuroprotectant "

10

抑制剂 & 化合物

3

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T24529	Neuroprotectant-7 Neuroprotectant7
	Neuroprotectant-7 is a neuroprotectant for Alzheimer's disease. It displays significant neuroprotection and antioxidative properties. It also can cross the blood-brain barrier.
TP1856	Colivelin	Beta Amyloid; STAT	JAK/STAT signaling; Neuroscience; Stem Cells
	Colivelin 是一种神经保护肽和 STAT3 的激活剂，是一种合成的杂合肽，可增强 humanin (HN) 的神经保护作用。它通过激活 STAT3 在体外抑制神经元死亡，具有潜力用于阿尔茨海默病和缺血性脑损伤的相关研究。
T3486	3-MATIDA	GluR; NMDAR	Neuroscience
	3-MATIDA 是一种有效的 mGluR-1 拮抗剂（IC50：6.3 μM，大鼠 mGluR-1a）。显示出 ≥ 40 倍于其他受体的选择性：mGluR-5、mGluR-2、mGluR-4 (mGluR-4a) (IC50 > 300 μM)、NMDA 和 GluR (AMPA) (IC50 = 250 μM)。 3-MATIDA 在体外培养的鼠皮质细胞和大鼠海马切片培养物中充当神经保护剂。
T69867	BN80933
	BN80933 is a dual inhibitor of lipid peroxidation and neuronal nitric oxide synthase; Neuroprotectant.
T35135	WN1316 WN 1316,WN-1316
	WN1316 is a unique neuroprotectant against oxidative injury, being a highly promising remedy for the treatment of amyotrophic lateral sclerosis (ALS).
T16371	OBA-09	Others	Others
	OBA-09 is a novel multimodal neuroprotectant oxopropanoyloxy benzoic acid. OBA-09 displays robust protective effects in the postischemic brain.
T70484	AD-35
	AD-35 is a neuroprotectant for treating Alzheimer’s diseases by significantly inhibiting the production and release of proinflammatory cytokines TNF-α and IL-1β.
T27626	Irampanel BIIR-561CL
	Irampanel is a neuroprotectant and anticonvulsant.
T68697	TC-1698 dihydrochloride
	TC-1698 dihydrochloride is a selective nicotinic α7 receptor agonist that also displays weak partial agonist/antagonist activity at β-subunit-containing receptors. This product is a neuroprotectant.
T69946	Ronopterin
	Ronopterin is a potent Nitric oxide synthase inhibitor and Neuroprotectant.

化合物

Neuroprotectant-7

Cat.No: T24529

Synonym: Neuroprotectant7

Cat.No: TP1856

Target: Beta Amyloid, STAT

Cat.No: T3486

Target: GluR, NMDAR

Cat.No: T69867

Cat.No: T35135

Synonym: WN 1316,WN-1316

Cat.No: T16371

Target: Others

Cat.No: T70484

Cat.No: T27626

Synonym: BIIR-561CL

TC-1698 dihydrochloride

Cat.No: T68697

Cat.No: T69946

Cat. No.	Product Name	Target	Signaling Pathways
T10933	D-Cysteine	Endogenous Metabolite; Antibacterial	Metabolism; Microbiology/Virology
	D-Cysteine 是一种大肠杆菌生长的有力抑制剂，是半胱氨酸的 D 型异构体。它由 D-氨基酸氧化酶介导产生 H2S，是一种对抗小脑共济失调的神经保护剂。 D-半胱氨酸可以抑制由变形链球菌和链球菌血红蛋白形成的两种生物膜的生长和致龋性。
T2S0843	Negletein 黄芩素-7-甲醚,7-O-Methylbaicalein,Baicalein-7-methylether	IL Receptor; TNF; NOS; Interleukin	Apoptosis; Immunology/Inflammation
	Negletein (7-O-Methylbaicalein) 一种神经保护剂，可增强神经生长因子的作用并诱导 PC12 细胞中的神经突生长。它通过抑制TNF-α和IL-1β表现出抗炎活性，其 IC50值分别为 16.4 和 10.8 μM。它还具有抗菌、抗缺氧和抗阿尔茨海默病活性。
T3871	Daucosterol Alexandrin,Sitogluside,β-Sitosterol β-D-glucoside,Eleutheroside A,西托糖苷	Glucosidase	Metabolism
	Daucosterol (Sitogluside) 是天然的甾醇体类化合物。

天然产物

Cat.No: T10933

Target: Endogenous Metabolite, Antibacterial

Cat.No: T2S0843

Synonym: 黄芩素-7-甲醚,7-O-Methylbaicalein,Baicalein-7-methylether

Target: IL Receptor, TNF, NOS, Interleukin

Cat.No: T3871

Synonym: Alexandrin,Sitogluside,β-Sitosterol β-D-glucoside,Eleutheroside A,西托糖苷

Target: Glucosidase

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