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7
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T7713 |
Benzyl nicotinate
烟酸苄酯,Rubriment,Pycaril |
GPR | Endocrinology/Hormones; GPCR/G Protein |
Benzyl nicotinate (Pycaril) 是血管扩张剂,可用于引起充血的一种活性成分。 | |||
T40418 |
DiO
DiOC18(3),3,3'-Dioctadecyloxacarbocyanine perchlorate |
Others | Others |
DiO (DiOC18(3)) 是一种荧光亲脂性示踪剂,可广泛用于标记细胞、细胞器、脂质体、病毒和脂蛋白。 | |||
T64561 |
DPhPC
|
Others | Others |
DPhPC 是一种用于合成脂质体,常用于人工膜基质。DPhPC 双层膜在没有孔/离子通道的情况下不允许离子泄漏。DPhPC可用于研究通道蛋白质和膜结构。 | |||
T36958 |
BODIPY 505/515
|
||
BODIPY 505/515 是一种亲脂性荧光探针,可定位到细胞内的脂质体,已被用于标记脂滴。BODIPY 505/515 已被用于电子显微镜、外荧光显微镜、共聚焦显微镜以及各种藻类物种的流式细胞仪应用中。 | |||
TF0112 |
DPPS
12-Dipalmitoyl-sn-glycero-3-PS sodium salt,DPPS-Na |
Others | Others |
DPPS (12-Dipalmitoyl-sn-glycero-3-PS sodium salt) 是一种阴离子二酰基磷脂,是磷脂酰丝氨酸(PS)的一种形式,是一种位于细胞膜内小叶的带负电荷的磷脂。DPPS 被用来制作阳离子囊泡和脂质体。 | |||
T8902 |
DOTMA
Trimethyl[2,3-(dioleyloxy)propyl]ammonium Chloride,N-(1-(2,3-dioleyloxy)propyl)-N,N,N-trimethylammonium |
Others | Others |
DOTMA (N-(1-(2,3-dioleyloxy)propyl)-N,N,N-trimethylammonium) 作为 tetra-methylated DOTA 类似物,是一种阳离子脂类,被用作基因治疗的非病毒载体。它已被用作脂质体的成分,可用于封装 siRNA、microRNA 和寡核苷酸,并用于体外基因转染。在体外和体内均表现出良好的基因转染效果。DOTMA 诱导脂质体上的正电荷,从而促进脂质体与细胞膜的有效相互作用。 | |||
T37563 |
C22 Ceramide (d18:1/22:0)
Cer(d18:1/22:0),C22 Ceramide,Ceramide (d18:1/22:0) |
||
C22 Ceramide (d18:1/22:0) (C22 Ceramide) 是一种从海绵Haliclona koremella 中分离出含有山嵛酸的长链神经酰胺,是一种内源性生物活性鞘脂。C22 Ceramide (d18:1/22:0) 可特异性抑制MCSR,降低离体大鼠肝线粒体和脂质体中 C16-神经酰胺通道的形成。 | |||
T39156 |
NHS-PEG1-SS-PEG1-NHS
NHS-PEG1-SS-PEG1-NHS |
||
NHS-PEG1-SS-PEG1-NHS 是一种可逆的、可用于生物大分子与活性小分子相互作用的链接剂。NHS-PEG1-SS-PEG1-NHS 可有效地用于蛋白质脂质体或纳米颗粒的连接。 | |||
TF0106 |
Cholesteryl Hemisuccinate Tris Salt
|
Apoptosis | Apoptosis |
Cholesteryl Hemisuccinate Tris Salt 是一种具有保肝和抗癌活性的酸性胆固醇酯,是一种含有柴胡皂苷-d的二棕榈酰磷脂酰胆碱脂质体中的膜稳定剂,可增强顺铂的抗癌功效。Cholesteryl hemisuccinate 具有抗肿瘤活性,抑制肿瘤生长,抑制对乙酰氨基酚 (AAP) 的肝毒性,预防 AAP 诱导的肝细胞凋亡。Cholesteryl hemisuccinate 可保护啮齿动物免受对乙酰氨基酚、阿霉素、四氯化碳、氯仿和半乳糖胺的毒性作用。 | |||
T82827 |
Bombolitin III
|
||
Bombolitin III为大黄蜂毒液中提取的抗菌肽,具有裂解红细胞和脂质体的功能。 | |||
T74317 |
18:1 EPC chloride
|
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18:1 EPC (chloride) 是一种卵磷脂酰胆碱,用于药物递送的脂质体研究。 | |||
T32451 |
L 644257
L-644257,6-Coham,Nmanchol,L644257 |
||
L 644257 is a synthetic glycolipid for study liposomes in vivo. | |||
T24457 | Methotrexate-gamma-aspartate | ||
Methotrexate-gamma-aspartate has growth inhibitory effects. It is used in antibody-targeted liposomes. | |||
T74943L | SARS-CoV-2-IN-25 disodium | ||
SARS-CoV-2-IN-25 (Compound CP026) disodium 作为一种有效的SARS-CoV-2刺突伪粒子转导抑制剂,其IC50值为1.6 μM,能够抑制包膜病毒和脂质体。 | |||
T37534 |
DMPAC-Chol
|
||
DMPAC-Chol is a cationic cholesterol derivative that has been used in liposome formation for gene transfection. Liposomes containing DMPAC-chol bind to DNA in a band shift assay and protect against serum nuclease degradation of DNA when used at lipsome:DNA ratios ranging from 2.5:1 to 10:1 w/w. DMPAC-Chol-containing liposomes also reduce viability of HepG2 cells by 63% when used at a concentration of 37.5 μg/ml. | |||
T74882 | DOPE-GA | ||
DOPE-GA 可用于制备脂质体,用于药物递送的研究。 | |||
T82826 |
Bombolitin IV
|
||
Bombolitin IV为大黄蜂毒液中提取的抗菌肽,具有裂解红细胞与脂质体的能力。 | |||
T37586 |
DMHAPC-Chol
|
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DMHAPC-Chol is a cationic cholesterol. Liposomes containing DMHAPC-chol have been used for DNA plasmid delivery in vitro and in vivo in a B16-F10 mouse xenograft model. Liposomes containing DMHAPC-chol are cytotoxic to B16-F10 cells when used at lipid concentrations greater than 20 μM. DMHAPC-Chol, as part of a lipoplex with DOPE , has also been used to deliver DNA into mouse lung via intratracheal injection, resulting in a heterogeneous distribution in the bronchi and bronchioles, and to delive... | |||
T77287 | DSPE-Rhodamine | ||
DSPE-Rhodamine,一种标记有罗丹明 B (Rhodamine B) 的磷脂DSPE,用于制备荧光标记的脂质体。 | |||
T21141 |
Decylene glycol
Decane-1,2-diol,AI3-16595,1,2-Decanediol |
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Decylene glycol is used as an antimicrobial agent in cosmetics. It also suppresses the fluidity of the hydrophobic and hydrophilic groups in the phospholipid membrane of liposomes. | |||
T82828 |
Bombolitin II
|
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Bombolitin II是一种抗菌肽,源自大黄蜂(Vespa crabro)的毒液,具有溶解红细胞和脂质体的能力。 | |||
T74139 | MPEG-2000-DSPE | ||
MPEG-2000-DSPE 是一种磷脂-聚乙二醇偶联物,具有亲水性和疏水性。MPEG-2000-DSPE 被用于脂质体的合成,增加脂质体表面的亲水性,从而延长脂质体在血液循环中的寿命,用于抗癌和抗疟活性分子的研究。 | |||
T74228 | DSPE-mPEG-2000 | ||
DSPE-mPEG-2000 是基于 PEG 的磷脂。DSPE-mPEG-2000 可用于合成传递肿瘤活性分子的脂质体。 | |||
T74321 |
16:0-18:1 EPC chloride
|
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16:0-18:1 EPC chloride 是一种阳离子脂质,用于药物递送中的脂质体。 | |||
T74320 |
14:0 EPC chloride
|
||
14:0 EPC chloride 是一种酰基阳离子脂质,用于药物递送中的脂质体。 | |||
T73733 |
(Rac)-1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol sodium
|
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(Rac)-1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol (sodium) 为阴离子磷脂, 主要应用于药物递送及脂质体合成。 | |||
TP1624 |
GPLGIAGQ TFA(109053-09-0 free base)
GPLGIAGQ TFA |
||
GPLGIAGQ TFA, is an MMP2-cleaved polypeptide that is used as a stimulus-sensitive connector in both liposomes and micelle nanoceroses for targeted therapy of tumors triggered by MMP2. | |||
T74322 | DOBAQ | ||
DOBAQ 是一种阳离子脂质,是一种对 pH 值敏感的脂质。DOBAQ 可用于脂质体应用于药物递送。 | |||
T38967 |
DSPE-PEG(2000)
|
||
MPEG-2000-DSPE sodium is a phospholipid PEG conjugate with hydrophilicity and hydrophobicity. It is utilized in liposome synthesis to enhance the hydrophilicity of liposomes, thereby prolonging their circulation in the bloodstream. This compound is commonly employed for the investigation of anticancer and antimalarial agents. | |||
T77270 | Cholesterol-PEG-Folate (MW 2000) | ||
Cholesterol-PEG-Folate (MW 2000) 是一种辅料,可用于制备叶酸偶联 PEG 脂质体。 | |||
T77285 | DSPE-PEG-NHS (MW 3400) | ||
DSPE-PEG-NHS (MW 3400)是一种 PEG 修饰的磷脂衍生物,可用于制备脂质体,用于递送 DNA 或mRNA 疫苗。 | |||
T82829 |
Bombolitin I
|
||
Bombolitin I为源自大黄蜂毒液的抗菌肽,具有裂解红细胞和脂质体的能力。 | |||
T74448 |
L343
|
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L343是一种可电离的阳离子类脂质,可用于合成脂质体,用于RNAi 疗法的全身递送。 | |||
T36357 |
Dimethyldioctadecylammonium (bromide)
|
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Dimethyldioctadecylammonium (DDA) is a cationic amphipathic lipid. DDA liposomes containing an Ag85B-ESAT-6 antigen induce antigen deposition at an intramuscular or subcutaneous injection site in mice, increasing immune cell exposure to the antigen. In a guinea pig model of M. tuberculosis infection, spleen bacterial load is reduced and lung and spleen lesion numbers are decreased when the mycobacterial lipid antigens Ac2SGL and PIM2 are administered in liposomes comprised of DDA and a synthetic... | |||
TP1231 |
β-Amyloid (29-40)
Amyloid beta-protein(29-40),β-Amyloid 29-40 |
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β-Amyloid (29-40) is a fragment of Amyloid-β peptide.Alzheimer's beta amyloid peptide (29-40/42) C-terminal fragments have physical and chemical properties related to those of fusion peptides of viral proteins. The fusion of liposomes can be induced by th | |||
T81337 |
Pyrromethene 650
PM650 |
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Pyrromethene 650 (PM650)为一种绿色荧光偏振示踪染料,常用于膜融合、裂解及隙缝结通讯的研究,并可检测细胞或脂质体的体积变化。 | |||
T74943 | SARS-CoV-2-IN-25 | ||
SARS-CoV-2-IN-25 (Compound CP026) 是一种有效的 SARS-CoV-2刺突伪粒子转导抑制剂,IC50为 1.6 μM。SARS-CoV-2-IN-25 抑制包膜病毒和脂质体。 | |||
T74187 | DSPE-PEG Carboxylic acid sodium (MW 2000) | ||
DSPE-PEG Carboxylic acid sodium (MW 2000) 为聚乙二醇脂质类化合物,主要功能是形成胶束,用作纳米粒子药物传递系统。此外,该化合物能有效延长脂质体在血液中的循环时间。 | |||
T38356 |
1,2-Dipalmitoyl-13C-sn-glycero-3-PC
|
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1,2-Dipalmitoyl-13C-sn-glycero-3-PC is intended for use as an internal standard for the quantification of 1,2-dipalmitoyl-sn-glycero-3-PC by GC- or LC-MS. 1,2-Dipalmitoyl-sn-glycero-3-PC (DPPC) is a zwitterionic glycerophospholipid commonly used in the formation of lipid monolayers, bilayers, and liposomes for use in a variety of applications.1,2,3,4 It has been used in the formation of proteoliposomes for implantation of γ-glutamyl transpeptidase into human erythrocyte membranes.3 Incorporation... | |||
T74168 | DSPE-PEG-Maleimide (MW 2000) | ||
DSPE-PEG-Maleimide (MW 2000) 是一种由 DSPE 和马来酰亚胺基团组成的 PEG 化合物。DSPE-PEG-Maleimide (MW 2000) 可用于构建脂质体。 | |||
T36784 |
Filipin II
|
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Filipin II is a polyene and an active component of the polyene antibiotic filipin complex . [1] It has broad-spectrum antifungal activity, reducing growth of various fungi, including B. dermatitidis, C. neoformans, and H. capsulatum (MICs = 1-10 μg/ml). Filipin II inhibits ADP-stimulated respiration in rat liver mitochondria when used at a concentration of 3.5 mg/ml. [2] It also induces hemolysis of liposomes in a cholesterol-independent manner (IC50 = 0.5 μg/ml).[3] | |||
T77284 |
DSPE-NHS
|
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DSPE-NHS 是一种具有两个疏水性脂质尾巴的生物共轭磷脂分子。DSPE-NHS 是一种在水溶液中形成脂质双分子层的自组装试剂。DSPE-NHS 可用于制备脂质体作为活性分子纳米载体。 | |||
T82644 |
Cyclo(Gly-His)
|
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Cyclo(Gly-His)为脂质体封装的环状二肽,显示出抗菌及抗癌特性。该化合物对HeLa细胞和MCF-7细胞表现出显著的细胞毒作用,IC50值分别为1.699 mM和0.358 mM。Cyclo(Gly-His)主要用于药物递送系统的研究领域。 | |||
T36616 |
DTUN
|
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DTUN is a lipophilic hyponitrite radical initiator.1It initiates co-autoxidation of STY-BODIPY-embedded egg phosphatidylcholine liposomes when used at a concentration of 0.2 mM. DTUN has been used in fluorescence-enabled inhibited autoxidation (FENIX) assays for the development of ferroptosis inhibitors and the study of antioxidants in lipid membranes.1,2 1.Shah, R., Farmer, L.A., Zilka, O., et al.Beyond DPPH: Use of fluorescence-enabled inhibited autoxidation to predict oxidative cell death res... | |||
T74567 | Phospholipid-PEG-Biotin (MW 10000) | ||
Phospholipid-PEG-Biotin (MW 10000)与Phospholipid-PEG-Biotin (MW 3400)均为磷脂与生物素通过线性PEG连接剂桥接形成的聚乙二醇衍生物。Phospholipid-PEG-Biotin (MW 3400) 能与亲和抗体相互作用,用于脂质体和细胞表面的修饰以及胰岛细胞的移植。 | |||
T77283 | DSPE-Mal | ||
DSPE-MAL是具有硫醇活性的磷脂化合物,拥有两个饱和脂肪酸,能够在水中自组装成脂质双层结构。该化合物常用于构建脂质体,作为活性分子的纳米载体。 | |||
T37454 |
C16 dihydro Ceramide (d18:0/16:0)
Ceramide (d18:0/16:0),Cer(d18:0/16:0),N-hexadecanoyl-D-erythro-Dihydrosphingosine,N-Palmitoyl Sphinganine |
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C16 dihydro Ceramide is a bioactive sphingolipid and precursor in the de novo synthesis of C16 ceramide (d18:0/16:0) that lacks the 4,5-trans double bond.[1] C16 dihydro Ceramide (0-46 nM) inhibits C16 ceramide-induced membrane permeabilization, measured as cytochrome C oxidation, in rat liver mitochondria in a concentration-dependent manner. It also inhibits C16 ceramide-induced channel formation in liposomes. C16 dihydro ceramide is biologically inactive as a single agent, lacking the ability ... | |||
T77280 |
DSPE-succinic acid
|
||
DSPE-succinic acid是一种具有羧酸末端的磷脂,能够通过其羧酸部分与胺发生反应,形成稳定的酰胺键。该化合物常用于纳米颗粒或脂质体的制备,用作活性分子的纳米载体。 | |||
T35503 |
(±)-5,7-Dimethyltocol
|
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(±)-5,7-Dimethyltocol is a form of tocopherol. It has similar antioxidant activity to α-tocol, but lower activity than γ-tocol, in antioxidant assays using menhaden oil or squalene as substrates. It also increases microviscosity of rat liver liposomes containing phosphatidylcholine (PC) by 70.6% when used at a molar ratio of 0.2 to PC. (±)-Dimethyltocol has been used as an internal standard for the quantification of 5,7-tocol, α- and γ-tocopherol, and α- and γ-tocopheryl quinone by HPLC. | |||
T74566 | Phospholipid-PEG-Biotin (MW 5000) | ||
Phospholipid-PEG-Biotin (MW 5000)为含有磷脂的PEG衍生物,适用于脂质体和细胞表面的修饰,及胰岛细胞移植。Phospholipid具亲水性“头部”与疏水性“尾部”结构,PEG为亲水性低毒聚合物,生物素则作为酶辅因子,用于蛋白质标记。 |
Cat. No. | Product Name | Target | Signaling Pathways |
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T19514 |
Phosphatidylcholines,soya
Soybean phosphatidylcholine |
Others | Others |
Phosphatidylcholines,soya (Soybean phosphatidylcholine) 是从大豆中提取的磷脂酰胆碱,可作为动物给药的载体,可用于脂质体的制备。 | |||
T9525 |
1,2-Dimyristoyl-sn-glycero-3-phosphocholine
DMPC,1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOL,二肉豆蔻酰磷脂酰胆碱(DMPC) |
Others | Others |
1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) 是一种用于脂质体和脂质双层的合成磷脂。它可用于脂质单层和双层的研究。 | |||
T9510 |
1,2-Distearoyl-sn-glycero-3-phosphorylcholine
DSPC,L-ALPHA-PHOSPHATIDYLCHOLINE, DISTEAROYL,1,2-Distearoyl-sn-glycero-3-PC,二硬脂酰磷脂酰胆碱 |
Others | Others |
1,2-Distearoyl-sn-glycero-3-phosphorylcholine (L-ALPHA-PHOSPHATIDYLCHOLINE, DISTEAROYL) 是一种脂质纳米颗粒(LNP) 系统中的脂质成分,可用于合成脂质体。 | |||
T19085 |
1-Palmitoyl-2-oleoyl-sn-glycero-3-PC
POPC,2-油酰-1-棕榈锡甘油-3-磷酸胆碱,1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine,Palmitoyloleoylphosphatidylcholine |
Others | Others |
1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (Palmitoyloleoylphosphatidylcholine) 是生物膜的主要成分,是一种磷脂。它用于脂质体的制备以及脂质双层的特性的研究。 | |||
T7773 |
DPPC
1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOL,二棕榈酸磷脂酰胆碱,129Y83 |
Endogenous Metabolite | Metabolism |
DPPC (129Y83) 是一种磷酸甘油酯,能够用于制备脂质体单层。DPPC-脂质体能够用作小鼠中诱导针对 GSL 抗原的免疫应答的递送载体。 | |||
T4709 |
(2S,3R,4S,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal hydrochloride
盐酸 D-甘露糖胺,D-Mannosamine hydrochloride |
Others; Endogenous Metabolite | Metabolism; Others |
(2S,3R,4S,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal hydrochloride (D-Mannosamine hydrochloride) 是内源性代谢产物的一种。 | |||
T74236 |
1-Oleoyl-2-palmitoyl-sn-glycero-3-PC
|
||
1-Oleoyl-2-palmitoyl-sn-glycero-3-PC,由油酸衍生,用于脂质体合成。 |