Powder: -20°C for 3 years | In solvent: -80°C for 1 year
C16 dihydro Ceramide is a bioactive sphingolipid and precursor in the de novo synthesis of C16 ceramide (d18:0/16:0) that lacks the 4,5-trans double bond.[1] C16 dihydro Ceramide (0-46 nM) inhibits C16 ceramide-induced membrane permeabilization, measured as cytochrome C oxidation, in rat liver mitochondria in a concentration-dependent manner. It also inhibits C16 ceramide-induced channel formation in liposomes. C16 dihydro ceramide is biologically inactive as a single agent, lacking the ability to induce apoptosis, cytochrome C release, or channel formation in phospholipid membranes in the absence of C16 ceramide.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
1 mg | ¥ 1,500 | 待询 | ||
5 mg | ¥ 4,280 | 待询 |
C16 dihydro Ceramide (d18:0/16:0) 的其他形式现货产品:
产品描述 | C16 dihydro Ceramide is a bioactive sphingolipid and precursor in the de novo synthesis of C16 ceramide (d18:0/16:0) that lacks the 4,5-trans double bond.[1] C16 dihydro Ceramide (0-46 nM) inhibits C16 ceramide-induced membrane permeabilization, measured as cytochrome C oxidation, in rat liver mitochondria in a concentration-dependent manner. It also inhibits C16 ceramide-induced channel formation in liposomes. C16 dihydro ceramide is biologically inactive as a single agent, lacking the ability to induce apoptosis, cytochrome C release, or channel formation in phospholipid membranes in the absence of C16 ceramide. |
别名 | Ceramide (d18:0/16:0), Cer(d18:0/16:0), N-hexadecanoyl-D-erythro-Dihydrosphingosine, N-Palmitoyl Sphinganine |
分子量 | 539.93 |
分子式 | C34H69NO3 |
CAS No. | 5966-29-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: Soluble
Chloroform:Methanol (5:1): Soluble
Ethanol: Soluble
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
C16 dihydro Ceramide (d18:0/16:0) 5966-29-0 Ceramide (d18:0/16:0) Cer(d18:0/16:0) d18:0/16:0 C-16 dihydro Ceramide (d18:0/16:0) C16 dihydro Ceramide Ceramide N-hexadecanoyl-D-erythro-Dihydrosphingosine N-Palmitoyl Sphinganine Inhibitor inhibitor inhibit