首页工具

登录

搜索结果

Search Results for " intercalator "

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T15507	Hycanthone Etrenol(mesylate),Win 249-33,海恩酮	DNA/RNA Synthesis; Topoisomerase; Parasite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Hycanthone (Etrenol(mesylate)) 是 Lucanthone 的生物活性代谢产物，是一种抗血吸虫病药。它是一个噻吨酮类 DNA 嵌入剂，可抑制 RNA 合成以及 DNA 拓扑异构酶 I 和 II。它通过直接蛋白质结合来抑制核酸生物合成并抑制嘌呤内切核酸酶1，KD 为 10 nM。
T2394	Pixantrone dimaleate 匹克生琼来酸盐,BBR-2778,Pixantrone Maleate,BBR 2778 dimaleate,马来酸匹衫琼	Topoisomerase	DNA Damage/DNA Repair
	Pixantrone dimaleate (Pixantrone Maleate) 是一种拓扑异构酶 II 的抑制剂和 DNA 嵌入剂，是一种实验性抗肿瘤药物。
T11872L	LMP744 hydrochloride NSC706744 hydrochloride,MJ-III65 hydrochloride	Topoisomerase	DNA Damage/DNA Repair
	LMP744 hydrochloride (NSC-706744 hydrochloride) 是一种是拓扑异构酶 1 抑制剂，显示出抗肿瘤的活性。
T1767	BMH-21 BMH21	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	BMH-21 是一种小分子 DNA 嵌入剂，可结合核糖体 DNA 并抑制 RNA 聚合酶 I (Pol I) 转录，具有抗癌活性。
T27085	Crisnatol mesylate BW-A-770U mesylate,BW-A-770U,BW-77OU-82,770U-82,770U-82 mesylate,BW-770
	Crisnatol, a potent and selective DNA intercalator, has potential anticancer activity.
T69245	Amikhelline
	Amikhelline is an antimitotic drug. It acts as a DNA intercalator and inhibits DNA polymerase.
T23750	AQ4 AQ-4,AQ 4
	AQ4 is an inhibitor of topoisomerase II. It is also a DNA intercalator.
T30425	BePI Be-PI,NSC 664711,NSC-664711,NSC664711,Be PI
	BePI can be a specific intercalator of both double and triple-helical DNA.
T11872	LMP744 NSC706744,MJ-III65	Others	Others
	LMP744 is a DNA intercalator and Topoisomerase I (Top1) inhibitor with antitumor activity.
T23817	BPTQ B-P-T-Q
	BPTQ is a typical intercalator of DNA that acts by inducing a dose-dependent inhibitory effect on the proliferation of cancer cells by arresting cells at the S and G2/M phase.
T25159	Bisnafide DMP 840
	Bisnafide is a Naphthalimide Analogue that acts as a DNA intercalator and topo II inhibitor. It is also an antiangiogenic agent that can normalize tumor vessels and promote the delivery of cytotoxic agents to tumor sites.
T18737	AcLysValCit-PABC-DMAE-SW-163D	Others	Others
	AcLysValCit-PABC-DMAE-SW-163D is a drug-linker conjugate for antibody-drug conjugates (ADCs), featuring a natural bis-intercalator, SW-163D, attached through an AcLysValCitPABC-DMAE linker[1].
T61351	Pixantrone hydrochloride
	Pixantrone (BBR 2778 (free base)) hydrochloride is a mitoxantrone analog compound that acts as a topoisomerase II inhibitor and DNA intercalator. It displays anti-tumor activity [1] [2].
T4047L	Bisantrene HCl CL216942,CL-216942,NSC-337766,CL 216942
	Bisantrene (CL-216942; NSC 337766) is a topoisomerase II poison and DNA intercalator. It can be used as a Rac1 inhibitor or model compound to study P-glycoprotein-mediated multi-drug resistance (MDR1). Bisantrene inserts and disrupts the configuration of
T60900	Pixantrone
	Pixantrone 具有抗肿瘤活性。它是一种 DNA 嵌入剂和拓扑异构酶 II 抑制剂。
T70609	Bisnafide mesylate
	Bisnafide is a Naphthalimide Analogue that acts as DNA intercalator and topo II inhibitor. It is also an antiangiogenic agent. Antiangiogenic agents can normalize tumor vessels and promote the delivery of cytotoxic agents to tumor sites.
T39548	Amustaline dihydrochloride S-303 dihydrochloride
	Amustaline (S-303) dihydrochloride is a nucleic acid-targeted alkylator recognized for its efficacy as a pathogen inactivation agent in blood components containing red blood cells. This compound comprises three key elements: an acridine anchor (a non-covalently bonding intercalator targeting nucleic acids), an effector (a bis-alkylator group that interacts with nucleophiles), and a linker (a flexible carbon chain with a labile ester bond, hydrolyzing at neutral pH to non-reactive products).
T73217	Crisnatol BWA770U
	Crisnatol (BWA770U) 为口服有效的抗癌剂，属于芳甲基氨基丙二醇类 DNA 插入剂。该化合物在体外对人类乳腺癌细胞表现出细胞毒性，而对正常人类皮肤成纤维细胞则无显著影响。
T36181	Quinaldopeptin
	Quinaldopeptin is a quinomycin antibiotic. It is active against a variety of bacteria, including S. pyogenes, S. aureus, C. perfringens, S. faecalis, E. coli, and K. pneumoniae (MICs = 0.2, 0.4, 0.8, 1.6, 3.1 and 6.3 μg/ml, respectively). It is cytotoxic to B16/F10 and Moser cells (IC50s = 0.0008 and 0.04 μg/ml, respectively) and increases survival in a P388 leukemia mouse model. Quinaldopeptin is a bis-intercalator depsipeptide (NPBID) that binds to and intercalates into DNA (Kd = 32 nM).
T36096	Thiocoraline
	Thiocoraline is a depsipeptide and DNAbis-intercalator originally isolated fromMicromonosporawith antibacterial and anticancer activities.1,2It is active against the Gram-positive bacteriaS. aureus,B. subtilis, andM. luteus(MICs = 0.05, 0.05, and 0.03 μg/ml, respectively) but not Gram-negativeE. coli,K. pneumoniae, orP. aeruginosa(MICs = >100 μg/ml for all).1Thiocoraline inhibits RNA and DNA polymerase and thymidylate synthase (IC50s = 6, 6, and 15 μg/ml, respectively), as well as RNA and DNA sy...

化合物

Cat.No: T15507

Synonym: Etrenol(mesylate),Win 249-33,海恩酮

Target: DNA/RNA Synthesis, Topoisomerase, Parasite

Pixantrone dimaleate

Cat.No: T2394

Synonym: 匹克生琼来酸盐,BBR-2778,Pixantrone Maleate,BBR 2778 dimaleate,马来酸匹衫琼

Target: Topoisomerase

LMP744 hydrochloride

Cat.No: T11872L

Synonym: NSC706744 hydrochloride,MJ-III65 hydrochloride

Target: Topoisomerase

Cat.No: T1767

Synonym: BMH21

Target: DNA/RNA Synthesis

Crisnatol mesylate

Cat.No: T27085

Synonym: BW-A-770U mesylate,BW-A-770U,BW-77OU-82,770U-82,770U-82 mesylate,BW-770

Cat.No: T69245

Cat.No: T23750

Synonym: AQ-4,AQ 4

Cat.No: T30425

Synonym: Be-PI,NSC 664711,NSC-664711,NSC664711,Be PI

Cat.No: T11872

Synonym: NSC706744,MJ-III65

Target: Others

Cat.No: T23817

Synonym: B-P-T-Q

Cat.No: T25159

Synonym: DMP 840

AcLysValCit-PABC-DMAE-SW-163D

Cat.No: T18737

Target: Others

Pixantrone hydrochloride

Cat.No: T61351

Cat.No: T4047L

Synonym: CL216942,CL-216942,NSC-337766,CL 216942

Cat.No: T60900

Bisnafide mesylate

Cat.No: T70609

Amustaline dihydrochloride

Cat.No: T39548

Synonym: S-303 dihydrochloride

Cat.No: T73217

Synonym: BWA770U

Cat.No: T36181

Cat.No: T36096

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼