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Cat. No.	Product Name	Target	Signaling Pathways
T64336	Izilendustat	HIF/HIF Prolyl-Hydroxylase	Chromatin/Epigenetic; Metabolism
	tert-butyl 4-[[1-[(4-chlorophenyl)methyl]-3-hydroxy-2-oxopyridin-4-yl]methyl]piperazine-1-carboxylate 是一种脯氨酰羟化酶抑制剂。
T22338	2,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide GDC046	Others; JAK	Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Others; Stem Cells
	2,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide (GDC046) 是一种具有口服活性的选择性TYK2抑制剂，对 TYK2、JAK1、JAK2 和 JAK3 的Ki 分别为 4.8、0.7、0.7 和 0.4 nM。
T60145	CCR6 antagonist 1	CCR	Immunology/Inflammation; Microbiology/Virology
	CCR6 antagonist 1 是一种 CCR6 拮抗剂，可抑制 CCL20/CCR6 信号通路。 CCR6 antagonist 1 可用于自身免疫介导的炎症性疾病的研究，如炎症性肠病 (IBDs)。
T11179	Elubrixin SB-656933	IL Receptor; CXCR	Autophagy; GPCR/G Protein; Immunology/Inflammation
	Elubrixin (SB-656933) 是一种有效和特异性的 CXCR2 和 IL-8 受体拮抗剂。 Elubrixin 可用于炎症性疾病的研究，例如炎症性肠病和气道炎症。
T17225	Vercirnon CCX282-B,维塞诺,GSK-1605786,Traficet-EN	CCR	Immunology/Inflammation; Microbiology/Virology
	Vercirnon (Traficet-EN) 是可口服的选择性 CCR9拮抗剂，可抑制 CCR9 介导的 Molt-4 细胞上 Ca2+移动和趋化性，用于炎症性肠病的研究。
T4666	TCJL37
	TCJL37 是一种有效的，选择性的，口服生物可利用的TYK2抑制剂，Ki 为 1.6 nM。TCJL37 可用于炎症性肠病 (IBD) 的研究。
T41121	Elubrixin tosylate SB-656933 tosylate,Elubrixin tosylate
	Elubrixin tosylate (SB-656933 tosylate) is a high-potency, selective, competitive, and reversible CXCR2 antagonist, as well as an antagonist of the IL-8 receptor. It effectively inhibits upregulation of neutrophil CD11b (with an IC50 of 260.7 nM) and shape change (with an IC50 of 310.5 nM). This compound holds promise for the study of inflammatory diseases, including inflammatory bowel disease and airway inflammation.
T60530	Mercaptoethylguanidine (MEG) (dihydrobromide)
	Mercaptoethylguanidine (MEG) dihydrobromide 是选择性的诱导型一氧化氮合酶抑制剂和过氧亚硝酸盐清除剂，在炎症性肠病研究中具有潜力。
T71179	LON63114
	LON63114, also known as FFA2-Agonist-1 is a selective orthosteric agonist of human FFA2. FFA2-Agonist-1 is potentially useful in the treatment of gastrointestinal disorders and inflammatory bowel diseases. LON63114 was reported in WO2011076732. This product has no formal name at the moment. For the convenience of communication, a temporal code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).
T63035	Izilendustat hydrochloride
	Izilendustat (hydrochloride) 是一种脯氨酰羟化酶 (prolyl hydroxylase) 的有效抑制剂，能够稳定缺氧诱导因子-1 α (HIF-1α) 和缺氧诱导因子-2 (HIF-2)。Izilendustat (hydrochloride) 具有潜力进行 HIF-1α 相关疾病的研究（包括外周血管疾病（PVD）、心力衰竭、冠状动脉疾病（CAD）、缺血、贫血、结肠炎和其他炎症性肠病）。